Choong Ho Shin

Growth after Hematopoietic Stem Cell Transplantation in Children with Acute Myeloid Leukemia

Previous studies have shown that hematopoietic stem cell transplantation (HSCT) may result in growth impairment. The purpose of this study was to evaluate the growth during 5 yr after HSCT and to determine factors that influence final adult height (FAH). We retrospectively reviewed the medical records of acute myeloid leukemia (AML) patients who received HSCT. Among a total of 37 eligible patients, we selected 24 patients who began puberty at 5 yr after HSCT (Group 1) and 19 patients who reached FAH without relapse (Group 2). In Group 1, with younger age at HSCT, sex, steroid treatment, hypogonadism and hypothyroidism were not significantly associated with growth impairment 5 yr after HSCT. History of radiotherapy (RT) significantly impaired the 5 yr growth after HSCT. Chronic graft-versus-host disease (cGVHD) only temporarily impaired growth after HSCT. In Group 2, with younger age at HSCT, steroid treatment and hypogonadism did not significantly reduce FAH. History of RT significantly reduced FAH. Growth impairment after HSCT may occur in AML patients, but in patients without a history of RT, growth impairment seemed to be temporary and was mitigated by catch-up growth.

Association between Physical Activity and Self-Rated Health among Pediatric Patients with Type 1 Diabetes Mellitus Who Lack Diabetes Care

<Heading Page> 1 Association between physical activity and self-rated health among pediatric patients with 2 type 1 diabetes mellitus who lack diabetes care 3 4 Author: Hyun Jin Kwona, Hyok Ju Maenga, Justin A. Haegeleb, Young Ah Leec, Choong Ho Shinc, 5 and Yeon Soo Kimd 6 aGeorgia State University, bOld Dominion University, cSeoul National University Children’s 7 Hospital, dSeoul National University 8 9 Author for correspondence 10 Corresponding Author: Hyun Jin Kwon, Ph.D. 11 Department of Kinesiology and Health, College of Education Human Development, Georgia State 12 University, Atlanta, GA 13 E-mail: jkwon11@gsu.edu 14 15 Author Note 16 One of the authors has identified that he has a potential conflict of interest in this study. 17 The university hospital institutional review board has approved his written plan to manage his 18 conflict of interest and prevent it from influencing the results. 19 20 Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 5 June 2018 doi:10.20944/preprints201806.0058.v1

Growth responses to growth hormone therapy in chilldren with growth failure, who showed normal growth hormone response to stimulation tests

Multiple linear regression models are built to predict either the adult height or the age at first menstruation, for girls with an idiopathic central precocious puberty.

Factors affecting growth response to growth hormone treatment in prepubertal patients with chronic renal failure

Multiple linear regression models are built to predict either the adult height or the age at first menstruation, for girls with an idiopathic central precocious puberty.