Christopher Bell
University of Colorado Boulder
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Christopher Bell.
The Journal of Physiology | 2006
Christopher Bell; Nicole R. Stob; Douglas R. Seals
β‐Adrenergic receptor (β‐AR) modulation of resting and postprandial energy expenditure (EE) is augmented in regularly exercising compared with sedentary adults, but the underlying physiological mechanisms are unknown. Differences in thermogenic responsiveness to β‐AR stimulation, perhaps secondary to reactive oxygen species (ROS) bioactivity, may be involved. To determine habitual exercise‐related differences in β‐AR thermogenic responsiveness and the possible influence of ROS, we measured the percentage increase in EE (ΔEE%; indirect calorimetry, ventilated hood method) above resting EE in response to non‐specific β‐AR stimulation (intravenous isoproterenol (isoprenaline): 6, 12 and 24 ng (kg fat‐free mass)−1 min−1) in 25 sedentary (11 males; 51 ± 4 years; body mass index 25.0 ± 0.8 kg m−2, maximal oxygen uptake 29 ± 1 ml kg−1 min−1 (mean ±s.e.m.)) and 14 habitually aerobic exercising (9 males, 46 ± 6 years, 23.1 ± 0.7 kg m−2, 44 ± 3 ml kg−1 min−1) healthy adults under normal (control) conditions and during acute intravenous administration of a potent antioxidant, ascorbic acid (vitamin C; 0.04 g (kg fat‐free mass)−1). ΔEE% was greater (P= 0.02) in the habitually exercising (8.6 ± 1.2, 12.9 ± 1.2, 20.0 ± 1.4) versus sedentary (6.3 ± 0.7, 10.4 ± 0.8, 16.0 ± 1.0) adults. Ascorbic acid increased (P= 0.01) ΔEE% only in the sedentary adults (to 9.5 ± 0.9, 12.4 ± 0.7, 18.5 ± 0.8), abolishing baseline group differences. ΔEE% was not related to the amount of body fat, sex, or any other baseline characteristic. Thermogenic responsiveness to β‐AR stimulation is augmented in habitually exercising adults. The mechanism is ascorbic acid dependent, suggesting that it may be linked to decreased ROS bioactivity. Our findings advance a novel mechanism by which habitual physical activity may modulate EE in humans, with potential implications for energy balance and body weight control.
American Journal of Physiology-endocrinology and Metabolism | 2001
Mary Beth Monroe; Douglas R. Seals; Linda F. Shapiro; Christopher Bell; David Johnson; Pamela Parker Jones
The Journal of Clinical Endocrinology and Metabolism | 2001
Christopher Bell; Douglas R. Seals; Mary Beth Monroe; Danielle S. Day; Linda F. Shapiro; David Johnson; Pamela Parker Jones
The Journal of Clinical Endocrinology and Metabolism | 2004
Christopher Bell; Danielle S. Day; Pamela Parker Jones; Demetra D. Christou; Darby S. Petitt; Kris Osterberg; Christopher L. Melby; Douglas R. Seals
The Journal of Clinical Endocrinology and Metabolism | 2003
Christopher Bell; Pamela Parker Jones; Douglas R. Seals
Archive | 2015
Nicole R. Stob; Christopher Bell; Marleen A. van Baak; Douglas R. Seals; Benjamin F. Miller; Matthew M. Robinson; Jennifer C. Richards; Matthew S. Hickey; Daniel R. Moore; Roger J. Paxton; Wyatt Voyles; Sean A. Newsom; Tyler K. Johnson; Jessica N. Kuzma; Mark C. Lonac
Archive | 2015
Kirsten A. Burgomaster; George J. F. Heigenhauser; Martin J. Gibala; Marco Toigo; Carsten Lundby; Robert A. Jacobs; Daniela Flück; Thomas Christian Bonne; Simon Bürgi; Peter Møller; Christopher Bell; Karyn L. Hamilton; Lacey M. Wood; Frederick F. Peelor; William E. Holmes; Marc K. Hellerstein; Dylan A. Hartley; Anna L. Klochak; Mark C. Lonac; Hunter Paris; Rebecca L. Scalzo; Garrett L. Peltonen; Scott E. Binns; Mahalakshmi Shankaran
Archive | 2015
Yoshiteru Hanai; Thomas Jue; Kazumi Masuda; Tatsuya Yamada; Yasuro Furuichi; Hisashi Takakura; Takeshi Hashimoto; Marieta V. Pancheva; Vladimir S. Panchev; Adelina V. Pancheva; Shane B. Kanatous; Rebecca L. Scalzo; Christopher Bell; Erich Gnaiger; Daniel P. Costa; Daniel E. Crocker; Adam J. Chicco; Catherine H. Le; Amber Schlater; Alex Nguyen; Spencer Kaye
Archive | 2015
Clare L. Weber; Donald Anthony Schneider; David Bishop; Johann Edge; Claire Thomas; Jacques Mercier; Christopher Bell; Karyn L. Hamilton; Lacey M. Wood; Frederick F. Peelor; William E. Holmes; Marc K. Hellerstein; Dylan A. Hartley; Anna L. Klochak; Mark C. Lonac; Hunter Paris; Rebecca L. Scalzo; Garrett L. Peltonen; Scott E. Binns; Mahalakshmi Shankaran
Archive | 2015
S. Mihic; D. MacLennan; Kevin E. Yarasheski; Mark A. Tarnopolsky; Gordon I. Smith; Bettina Mittendorfer; Nicholas A. Burd; Bart Pennings; Bart B. L. Groen; Annemie P. Gijsen; Joan M. G. Senden; Christopher Bell; Karyn L. Hamilton; Lacey M. Wood; Frederick F. Peelor; William E. Holmes; Marc K. Hellerstein; Dylan A. Hartley; Anna L. Klochak; Mark C. Lonac; Hunter Paris; Rebecca L. Scalzo; Garrett L. Peltonen; Scott E. Binns; Mahalakshmi Shankaran