Christopher P. Hogrefe
University of Iowa Hospitals and Clinics
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Publication
Featured researches published by Christopher P. Hogrefe.
Journal of Emergency Medicine | 2015
Nicholas M. Mohr; Andrew J. Stoltze; Karisa K. Harland; Jon Van Heukelom; Christopher P. Hogrefe; Azeemuddin Ahmed
BACKGROUNDnJournal club is a standard component of residency education. Journal club focuses on review and interpretation of the medical literature with varying degrees of evidence-based medicine (EBM) education.nnnOBJECTIVESnTo evaluate learning of EBM principles with an EBM curriculum implemented as a component of journal club. EBM competency was established using the Fresno test, a validated 12-question instrument of short-answer and essay-style questions to assess competency in EBM.nnnMETHODSnAn EBM curriculum was implemented that consisted of a focus on EBM topics (e.g., study validity, bias, confidence intervals, search strategies) using a structured journal club format using a peer instruction model. The Fresno test was used prior to and after the implementation of the first year of this curriculum to measure effectiveness of the intervention. A hierarchical multivariable model using generalized estimating equations was used to account for repeated measures in the primary outcome of change in total Fresno test score.nnnRESULTSnThe total test scores did not increase significantly (105.4 vs. 120.9, p = 0.058) in the before-after analysis. The only subscore showing improvement was interpretation of study validity (32.1 vs. 40.4 points, p = 0.03). Attendance was significantly associated with Fresno test score, with those attending ≥ 6/11 sessions (55%) scoring 28.2 points higher (p = 0.003), and those attending fewer than six sessions scoring only 1.9 points higher (p = 0.81) than in the preintervention group.nnnCONCLUSIONnAn EBM curriculum implemented as part of journal club improves performance on the Fresno test among residents who attended at least six journal club sessions.
Annals of Pharmacotherapy | 2012
Brett A. Faine; Christopher P. Hogrefe
A quick way for a clinical pharmacist to eliminate himself or herself from “employee of the month” consideration is to mention the term medication shortage. Even with training geared toward maximizing resources, the cumulative disappearance of a plethora of medications for the treatment of nausea, vomiting, and/or primary headaches is almost too much for emergency medicine physicians to manage. With prochlorperazine, metoclopramide, promethazine, and ondansetron in increasingly short supply, it is time for the Food and Drug Administration to revisit droperidols black box warning driven by Q Tc interval prolongation, given its questionable validity, and restore droperidols place in the armamentarium of emergency medicine physicians.
American Journal of Emergency Medicine | 2012
Brett A. Faine; Christopher P. Hogrefe; Jon Van Heukelom; Jamie Smelser
OBJECTIVEnThe aim of this study was to describe the use and efficacy of low-dose (≤2 mg) droperidol for the treatment of primary headaches (ie, migraine, cluster, tension-type headache and trigeminal autonomic cephalalgias, and other primary headaches) in the emergency department (ED).nnnMETHODSnA report was generated from a pharmacy database to identify all adult patients who received low-dose droperidol in the ED over a 7-month period; a subsequent retrospective chart review was conducted. Low-dose droperidol was defined as a cumulative dose of ≤2 mg. Patients who received droperidol for any other reason than the treatment of a headache were excluded. Data were analyzed descriptively.nnnRESULTSnSeventy-three cases in which droperidol was administered for the treatment of a headache were identified over the 7-month period. Most doses (92%) administered were 1.25 mg or less. Fifty-three patients (73%) had complete resolution or significant improvement of headache symptoms as subjectively or objectively (eg, numerical pain scale) documented by the treating physician. Eight patients (11%) had minimal improvement in their headaches symptoms; 12 patients (16%) received no relief after the administration of droperidol. The average time to discharge from the ED was 94.8 ± 67.2 minutes. No cardiac arrhythmias were noted. Other adverse events included 2 cases of extrapyramidal side effects; one patient reported restlessness/anxiousness and the other patient had dystonia.nnnCONCLUSIONnThe administration of low-dose (≤2 mg) droperidol may be safe and effective for the treatment of primary headaches in the ED.
Clinical Journal of Sport Medicine | 2014
Timothy W. Thomsen; Christopher P. Hogrefe; Mederic M. Hall; Annunziato Amendola
Tenosynovial (extra-articular) chondromatosis (TC) is a condition characterized by the cartilaginous proliferation of synovial cells derived from the synovial lining of bursa and tendon sheaths. These lesions are often multinodular and most commonly present with complaints of swelling or pain. Treatment of TC primarily entails surgical excision. There are no known reports of TC in collegiate athletes. We present a case of TC in a Division I tennis player.
Current Reviews in Musculoskeletal Medicine | 2018
Ross Mathiasen; Christopher P. Hogrefe
Purpose of ReviewTo provide a primary care perspective regarding the evaluation and management of shoulder pain and rotator cuff tears.Recent FindingsIn the primary care setting, rotator cuff pathology is commonly encountered. Information regarding the risks of oral medications for the management of the associated pain keeps mounting. Partial-thickness rotator cuff tears remain difficult to diagnose with a single imaging modality. Musculoskeletal education in medical schools and non-orthopaedic residency and fellowship training programs continues to be an area for additional improvement.SummaryIn the primary care office, the initial evaluation of shoulder pain should include a thorough musculoskeletal evaluation in order to identify the source of the pain (e.g., shoulder, cervical spine, chest wall), as well as the development of an initial treatment plan. Access to imaging modalities such as ultrasound and MRI can vary depending on the resources available in the primary care setting. The identification of patients who may benefit from early surgical referral is imperative for optimizing outcomes.
American Journal of Physiology-heart and Circulatory Physiology | 2008
Eric W. Dickson; Christopher P. Hogrefe; Paula S. Ludwig; Laynez W. Ackermann; Lynn L. Stoll; Gerene M. Denning
Annals of Emergency Medicine | 2012
Christopher P. Hogrefe; A.S. Nugent; Karisa K. Harland; H.R. House
Annals of Emergency Medicine | 2011
Brett A. Faine; Christopher P. Hogrefe; J. Van Heukelom; J. Smelser
The FASEB Journal | 2007
Christopher P. Hogrefe; Paula S. Ludwig; Gerene M. Denning; Thomas J. Barna; Laynez W. Ackermann; Lynn L. Stoll; Neal L. Weintraub; Eric W. Dickson
The FASEB Journal | 2007
Gerene M. Denning; Laynez W. Ackermann; Chantal Allamargot; Thomas J. Barna; Paula S. Ludwig; John G. Armstrong; Christopher P. Hogrefe; Lynn L. Stoll; Kenneth C Moore; Neal L. Weintraub; Eric W. Dickson