Claudimar Pereira da Veiga

Relationships Among Knowledge Management, Organisational Innovativeness and Performance: Covariance-Based Versus Partial Least-Squares Structural Equation Modelling

The relationships among effective knowledge management (KM), organisational innovativeness (OI), market orientation (MO) and organisational performance (OP) have been explored in the literature. These constructs are generally analysed in pairs, such as the influence of KM on OI, or KM on OP, and other combinations, but the relationships among the full set of constructs in question are not fully understood yet. In the extant literature, the relationships among them are analysed for the most part with covariance-based structural equation modelling (CB-SEM). Partial least-squares (PLS) path modelling is a component-based approach to SEM that is not as widely used as CB-SEM, but it has the potential to allow increased flexibility in handling various modelling problems in comparison with CB models, particularly for predictive and exploratory purposes. This paper aims to verify whether the PLS method could confirm or reject the results of the more restrictive covariance-based method in modelling the relationshi...

An Artifact for Evaluating the Quality of Health Service Providers: Evidence From Brazil

The aim of this article is to present an artifact for evaluating the quality and performance of service providers in the field of health care: the UNIPLUS Program. To verify the scientific nature of the artifact and ensure that it meets the criteria set by the community and the environment, the premises of Design Science Research (DSR) were used. As this research field lacks empirical evidence, the artifact was tested from 2013 to 2015 with 25 health care service providers from different categories, with an emphasis on hospitals and clinics located in 7 cities in the south of Brazil. This article makes 3 main contributions to the field: (1) the artifact can be applied to any health insurance operator in Brazil and other countries, as it meets the legal norms and requirements established by current legislation; (2) it helps health service providers by generating information that identifies shortfalls and possibilities for improvement for every aspect analyzed in the evaluation process; and (3) it uses the DSR methodology in an evaluation artifact that evaluates the quality and performance of services in the field of health care. The artifact proved to be adequate for the purpose in question, helping to improve the quality of care and institutional performance.

Concern over cost of and access to cancer treatments: A meta-narrative review of nivolumab and pembrolizumab studies

BACKGROUNDnA better understanding of the modulation of the immune system has resulted in the development of new classes of antitumor agents such as nivolumab and pembrolizumab. Despite the proven effectiveness and tolerability of these new drugs for specific types of cancer, the high cost of treatment has affected their accessibility.nnnOBJECTIVEnThe aim of this study is to conduct a meta-narrative review of studies that have addressed the concerns that have been voiced regarding the cost of and access to nivolumab and pembrolizumab in oncology health care. This meta-narrative review attempts to answer the following questions: (1) which papers have considered this broad topic area?; (2) what are the main empirical/theoretical findings?; and (3) what insights can be drawn by combining and comparing findings from different papers?nnnMETHODS AND DATA SOURCEnA meta-narrative review has been conducted in 5 research databases (Web of Science, Science Direct, Scopus, Embase and Pubmed) without time limitations up to January of 2017 to address concerns related to the cost of and access to nivolumab and pembrolizumab in oncology health care. From each research base, articles were selected that had a key word related to the theme of pharmacoeconomics and nivolumab or pembrolizumab in any field of scientific work. The research questions were analyzed through the application of a meta-narrative review approach and the use of a convergence-coding matrix to summarize similarities and differences directly related to the research topic between the different papers.nnnKEY FINDINGSnThe first contribution of this meta-narrative review is that it summarizes economic-based works on the use of nivolumab and pembrolizumab, particularly for three therapeutic indications: melanoma, NSCLC and RCC. In general, despite the clinical benefit of nivolumab and pembrolizumab being well accepted and proven by scientific works, the published studies show that there are contradictory results with regard to the cost-effectiveness of these anti-PD-1s. The regulatory, economic and epidemiological variations mean that healthcare costs for cancer patients vary greatly from country to country and according to the type of tumor. The second contribution has to do with the recommendations for the development of high quality process for pharmacoeconomic analyses, especially in the new field of immuno-oncology. Finally, the third contribution is with regard to recommendations for the sustainable use of immunotherapies.nnnCONCLUSIONSnGiven the revolution in cancer therapy in recent years, the efficient allocation of existing resources is essential for healthcare systems to meet the evolving needs of populations and remain sustainable in the long term. The application of high quality information that stems from scientific evidence and economic modeling can help considerably to make the healthcare system sustainable over time mainly due to a higher number of therapeutic indications or more countries giving regulatory approval for the use of new and expensive cancer drugs.

Econometric analysis of cointegration and causality between markets prices toward futures contracts: Evidence from the live cattle market in Brazil

Abstract The objective of this study is to investigate evidence of cointegration and causality between the market price of the live cattle in Brazil and the prices of the respective derivatives traded on BM&FBOVESPA – São Paulo, Brazil. The Johansen test was used to analyze evidence of cointegration between markets. The cointegration of these markets and their bidirectional causality signal to decision-makers in this agribusiness that the variations in BM&FBOVESPA futures contracts cause changes in the prices of the spot prices, as well as the spot prices cause to the futures contracts of B&MFBOVESPA.