Claudio Gonçalves de Albuquerque

Influência da mobilização precoce na força muscular periférica e respiratória em pacientes críticos

OBJECTIVE:To evaluate the effects of an early mobilization protocol on respiratory and peripheral muscles in critically ill patients. METHODS: A randomized controlled clinical trial was conducted with 59 male and female patients on mechanical ventilation. The patients were divided into a conventional physical therapy group (control group, n=14) that received the sectors standard physical therapy program and an early mobilization group (n=14) that received a systematic early mobilization protocol. Peripheral muscle strength was assessed with the Medical Research Council score, and respiratory muscle strength (determined by the maximal inspiratory and expiratory pressures) was measured using a vacuum manometer with a unidirectional valve. Systematic early mobilization was performed on five levels. RESULTS: Significant increases were observed for values for maximal inspiratory pressure and the Medical Research Council score in the early mobilization group. However, no statistically significant improvement was observed for maximal expiratory pressure or MV duration (days), length of stay in the intensive care unit (days), and length of hospital stay (days). CONCLUSION: The early mobilization group showed gains in inspiratory and peripheral muscle strength.

Protocol of Mensuration to Avaliation of Indicators of Somatic Development of Wistar Rats

Evaluaciones de peso y perimetro cefalico son muy utilizadas para el estudio del crecimiento y desarrollo en humanos. Medidas semejantes, denominadas murinometricas, han sido un recurso eficiente para el estudio de los efectos de manipulaciones nutricionales y farmacologicos sobre el desarrollo somatico en ratas. El objetivo de este trabajo fue describir un metodo de evaluacion que ofrece mayor exactitud en la recoleccion de los datos, en el estudio del desarrollo somatico en ratas Wistar. Fueron realizadas medidas en el eje latero-lateral del craneo (ELLC); eje antero-posterior del craneo (EAPC); eje longitudinal (EL) y largo de la cola (LC), en 60 ratas Wistar, durante el periodo de amamantacion. Se observo, como metodo mas adecuado de medicion, el que se relaciona con puntos anatomicos predefinidos, uso del asta adecuada del instrumento de medida (paquimetro), asi como la precision de su exactitud

Determining respiratory system resistance and reactance by impulse oscillometry in obese individuals

Objective: To evaluate peripheral respiratory system resistance and reactance (Rrs and Xrs, respectively) in obese individuals. Methods: We recruited 99 individuals, dividing them into four groups by body mass index (BMI): < 30.0 kg/m2 (control, n = 31); 30.0-39.9 kg/m2 (obesity, n = 13); 40.0-49.9 kg/m2 (severe obesity, n = 28); and ≥ 50.0 kg/m2 (morbid obesity, n = 13). Using impulse oscillometry, we measured total Rrs, central Rrs, and Xrs. Peripheral Rrs was calculated as the difference between total Rrs and central Rrs. All subjects also underwent spirometry. Results: Of the 99 individuals recruited, 14 were excluded because they failed to perform forced expiratory maneuvers correctly during spirometry. The individuals in the severe obesity and morbid obesity groups showed higher peripheral Rrs and lower Xrs in comparison with those in the two other groups. Conclusions: Having a BMI ≥ 40 kg/m2 was associated with a significant increase in peripheral Rrs and with a decrease in Xrs.