Cornelia Guran

Alginate and Sulfanilamide Based DDS with Antibacterial Activity

The aim was to obtain alginate based, biological active delivery systems, with prolonged release of sulfanilamide. The influences of alginate gel concentration as well as the influence of sulfanilamide content were studied. The presence of sulfanilamide assures antimicrobial activity while alginate and magnetite are responsible with the slow release kinetic. The presence of magnetite is also important because allows magnetic field guidance of the alginate/Fe3O4/sulfanilamide beads. The obtained DDS were characterized by FTIR, SEM, release profile in saline solution (0.9% NaCl), and antimicrobial activity against Escherichia coli.

Antimicrobial coatings — obtaining and characterization

In this paper, we present inorganic–organic hybrid coatings with polymer matrix (water soluble) that contain silver nanoparticles (AgNPs). The structure and morphology of coating materials were determined by infrared spectroscopy (FT–IR) and scanning electron microscopy (SEM). Therefore, the antimicrobial activities and mechanisms of coatings for several pathogenic bacteria (Bacilius cereus and Staphylococcus aureus) were investigated. It was demonstrated that the obtained material with silver nanoparticles keep their antimicrobial effect even if they are subjected to several cycles of washing with water and detergent.

Tris[4-(2-pyridylmethyl­eneamino)phenol]iron(II) bis­(perchlorate)

In the title compound, [Fe(C12H10N2O)3](ClO4)2, the metal center is coordinated by six N atoms from the three bidentate chelating ligands in a distorted octahedral coordination geometry, with overall formation of the meridional (OC-6-21) isomer. Intermolecular O—H⋯O hydrogen bonds between the hydroxyl groups of the cation and the counter-anions form an infinite one-dimensional chain in the c-axis direction.

3,6-Diaminoacridinium perchlorate

The structure of the title compound, C13H12N3+·ClO4−, reveals a twofold axis through the ring N and para-C atoms; a twofold rotation axis also passes through the Cl atom. The structure of the organic fragment is similar to that of homologous heterocyclic systems. The organic cations and perchlorate anions self-assemble in the solid state through C—H...O and N—H...O hydrogen bonds, leading to a two-dimensional layer parallel to the (112) plane. The layers are stacked along the c axis through offset π–π interactions between cations from different layers (the distance between the planes through two cations is 3.35 A), resulting in a three-dimensional supramolecular architecture.

Strategies for the Synthesis of New Materials Based on Squarate-Substituted Phosphazenes and d or f Metals

We report the synthesis of a new organo-inorganic ring system, squarate-substituted cyclophosphazene derivative 3. The isolated product was characterized by means of elemental analysis, IR and 13C-NMR spectroscopy. Elemental analysis, molar conductivity data, IR and electronic spectra support the general formulae of obtained complexes: [M2(3)(OH2)4(ClO4)2](ClO4)4, (M=Fe3+, Cr3+), [M2(3)(OH2)8Cl4]Cl2, (M=Eu3+, Ce3+).