Craig McNally

The tolerance of the frontal bone to blunt impact

The current understanding of the tolerance of the frontal bone to blunt impact is limited. Previous studies have utilized vastly different methods, which limits the use of statistical analyses to determine the tolerance of the frontal bone. The purpose of this study is to determine the tolerance of the frontal bone to blunt impact. Acoustic emission sensors were used to provide a noncensored measure of the frontal bone tolerance and were essential due to the increase in impactor force after fracture onset. In this study, risk functions for fracture were developed using parametric and nonparametric techniques. The results of the statistical analyses suggest that a 50% risk of frontal bone fracture occurs at a force between 1885 N and 2405 N. Subjects that were found to have a frontal sinus present within the impacted region had a significantly higher risk of sustaining a fracture. There was no association between subject age and fracture force. The results of the current study suggest that utilizing peak force as an estimate of fracture tolerance will overestimate the force necessary to create a frontal bone fracture.

Dynamic material properties of the human sclera

As a result of trauma, approximately 30,000 people become blind in one eye every year in the United States. A common injury prediction tool is computational modeling, which requires accurate material properties to produce reliable results. Therefore, the purpose of this study was to determine the dynamic material properties of the human sclera. A high-rate pressurization system was used to create dynamic pressure to the point of rupture in 12 human eyes. Measurements were obtained for the internal pressure, the diameter of the globe, the thickness of the sclera, and the changing coordinates of the optical markers using high-rate video. A relationship between true stress and true strain was determined for the sclera tissue in two directions. It was found that the average maximum true stress was 13.89+/-4.81 MPa for both the equatorial and meridional directions, the average maximum true strain along the equator was 0.041+/-0.014, and the average maximum true strain along the meridian was 0.058+/-0.018. Results show a significant difference in the maximum strain in the equatorial and meridional directions (p=0.02). In comparing these data with previous studies, it is concluded that the human sclera is both anisotropic and viscoelastic. The dynamic material properties presented in this study can be used for advanced models of the human eye to help prevent eye injuries in the future.

Can footwear affect achilles tendon loading

Objective: To investigate the effects of footwear on Achilles tendon tension by directly measuring Achilles tendon tension and dorsiflexion range of motion. Design: A total of 48 matched pair tests were performed comparing the effects of shoe type (high-top vs low-top) for each shoelace configuration (tied vs untied). These were performed using the Achilles tendons of 4 human cadaver lower extremities that were instrumented with a customized load cell designed to measure tension. The lower extremity was inverted in a custom testing apparatus designed to inertially invoke dorsiflexion of the foot, putting the Achilles tendon in tension. Setting: Research laboratory. Patients: Left and right lower extremities of 2 human cadavers. Interventions: None. Independent variables were shoe type and shoelace configuration. Main Outcome Measures: Achilles tendon tension and dorsiflexion range of motion. Results: High-top shoes significantly reduced peak Achilles tendon tension by an average of 9.9% when compared with low-top shoes. Tied laces significantly reduced peak tension for low-top (3.7%) and high-top (12.8%) shoes when compared with untied laces. With tied laces, high-top shoes significantly reduced peak dorsiflexion angle by an average of 7.2% when compared with low-top shoes. Tied laces with high-top shoes significantly reduced peak dorsiflexion angle by an average of 4.7% when compared with untied laces. A P value of 0.05 was determined to be significant. Conclusions: This study offers valuable insight that footwear can affect Achilles tendon loading during dorsiflexion.

Dynamic tensile properties of human placenta

Automobile crashes are the largest cause of injury death for pregnant females and the leading cause of traumatic fetal injury mortality in the United States. Computational models, useful tools to evaluate the risk of fetal loss in motor vehicle crashes, are based on a limited number of quasi-static material tests of the placenta. This study presents a total of 20 dynamic uniaxial tensile tests on the maternal side of the placenta and 10 dynamic uniaxial tensile tests on the chorion layer of the placenta. These tests were completed from 6 human placentas to determine material properties at a strain rate of 7.0 strains/s. The results show that the average peak strain at failure for both the maternal portion and the chorion layer of the placenta are similar with a value of 0.56 and 0.61, respectively. However, the average failure stress for the chorion layer, 167.8 kPa, is much higher than the average failure stress for the placenta with the chorionic plate removed, 18.6 kPa. This is due to differences in the structure and function of these layers in the placenta. In summary, dynamic loading data for the placenta have been determined for use in computational modeling of pregnant occupant kinematics in motor vehicle crashes. Moreover the computational model should utilize the material properties for the placenta without the chorion layer.

The tolerance of the maxilla to blunt impact

This study reports the results of 38 infraorbital maxilla impacts performed on male cadavers. Impacts were performed using an unpadded, cylindrical impactor (3.2 kg) at velocities between 1 and 5 m/s. The peak force and acoustic emission data were used to develop a statistical relationship of fracture risk as a function of impact force. Acoustic emission sensors were used to provide a noncensored measure of the maxilla tolerance and were essential due to the increase in impactor force after fracture onset. Parametric and nonparametric techniques were used to estimate the risk of fracture tolerance. The nonparametric technique produced an estimated 50% risk of fracture between 970 and 1223 N. The results obtained from the parametric and nonparametric techniques were in good agreement. Peak force values achieved in this study were similar to those of previous work and were unaffected by impactor velocity. The results of this study suggest that an impact to the infraorbital maxilla is a load-limited event due to compromise of structural integrity.

High-Rate Internal Pressurization of Human Eyes to Predict Globe Rupture

OBJECTIVE To determine the dynamic rupture pressure of the human eye by using an in vitro high-rate pressurization system to investigate blunt-impact eye injuries. METHODS Internal pressure was dynamically induced in the eye by means of a drop-tower pressurization system. The internal eye pressure was measured with a small pressure sensor inserted into the eye through the optic nerve. A total of 20 human eye tests were performed to determine rupture pressure and characterize rupture patterns. RESULTS The high-rate pressurization resulted in a mean (SD) rupture pressure of 0.97 (0.29) MPa (7275.60 [2175.18] mm Hg). A total of 16 eyes ruptured in the equatorial direction, whereas 4 ruptured in the meridional direction. There was no significant difference in the rupture pressure between the equatorial and meridional directions (P= .16). CONCLUSION As the loading rate increases, the rupture pressure of the human eye increases. CLINICAL RELEVANCE Eye injuries are expensive to treat, given that the estimated annual cost associated with adult vision problems in the United States is

Effect of strain rate on the tensile material properties of human placenta.

51.4 billion. Determining globe rupture properties will establish injury criteria for the human eye to prevent these common yet devastating injuries.

A Multi-Modality Image Data Collection Protocol for Full Body Finite Element Model Development

Automobile crashes are the largest cause of injury death for pregnant females and the leading cause of traumatic fetal injury mortality in the United States. Computational models, useful tools to evaluate the risk of fetal loss in motor vehicle crashes, are based on a limited number of quasistatic material tests of the placenta. This study presents a total of 64 uniaxial tensile tests on coupon specimens from six human placentas at three strain rates. Material properties of the placental tissue were evaluated at strain rates of 0.07/s, 0.70/s, and 7.00/s. The test data have average failure strains of 0.34, 0.36, and 0.37, respectively. Failure stresses of 10.8 kPa, 11.4 kPa, and 18.6 kPa correspond to an increase in strain rate from 0.07/s to 7.0/s. The results indicate rate dependence only when comparing the highest strain rate of 7.0/s to either of the lower rates. There is no significant rate dependence between 0.07/s and 0.70/s. When compared with previous testing of placental tissue, the current study addresses the material response to more strain rates as well as provides a much larger set of available data. In summary, tensile material properties for the placenta have been determined for use in computational modeling of pregnant occupant kinematics in events ranging from low impact activities to severe impacts such as in motor vehicle crashes.

Differences in Impact Performance of Bicycle Helmets During Oblique Impacts

This study outlines a protocol for image data collection acquired from human volunteers. The data set will serve as the foundation of a consolidated effort to develop the next generation full-body Finite Element Analysis (FEA) models for injury prediction and prevention. The geometry of these models will be based off the anatomy of four individuals meeting extensive prescreening requirements and representing the 5th and 50th percentile female, and the 50th and 95th percentile male. Target values for anthropometry are determined by literature sources. Because of the relative strengths of various modalities commonly in use today in the clinical and engineering worlds, a multi-modality approach is outlined. This approach involves the use of Computed Tomography (CT), upright and closed-bore Magnetic Resonance Imaging (MRI), and external anthropometric measurements. CT data provide sub-millimeter resolution and slice thickness of the subjects in the supine and an approximately seated position. Closed-bore MRI complements CT data by providing high-resolution images with improved contrast between soft tissues. MRI pulse sequences that image fat-water interfaces out-of-phase are used to enhance contrast and facilitate segmenting organ and muscle boundaries. Upright MRI data complement closed-bore data by enabling quantification of morphological changes that occur when a subject is oriented upright with respect to gravity. The final component in this suite of image data is a set of external anthropometry (EA) measurements. EA measurements include three-dimensional point cloud acquisition of external bony landmarks as well as surface contours. These data serve as a valuable geometric validation tool for the assembled full-body FEA models. Protocol development results, including preliminary image data sets, in-plane resolution and slice thickness achieved for each modality, pulse sequence designs for MRI acquisition protocols, and custom positioning systems used in image acquisition are presented. The approach outlined in this study is expected to provide sufficient data to develop models in both the seated and standing posture. This suite of imaging and anthropometry data will serve as a strong foundation for the collaborative development of a group of fullbody FEA models for injury prediction in the coming years. A Multi-Modality Image Data Collection Protocol for Full Body Finite Element Model Development

Material Properties of Human Rib Cortical Bone from Dynamic Tension Coupon Testing

Cycling is a leading cause of sport-related head injuries in the U.S. Although bicycle helmets must comply with standards limiting head acceleration in severe impacts, helmets are not evaluated under more common, concussive-level impacts, and limited data are available indicating which helmets offer superior protection. Further, standards evaluate normal impacts, while real-world cyclist head impacts are oblique-involving normal and tangential velocities. The objective of this study was to investigate differences in protective capabilities of ten helmet models under common real-world accident conditions. Oblique impacts were evaluated through drop tests onto an angled anvil at common cyclist head impact velocities and locations. Linear and rotational accelerations were evaluated and related to concussion risk, which was then correlated with design parameters. Significant differences were observed in linear and rotational accelerations between models, producing concussion risks spanning >50% within single impact configurations. Risk differences were more attributable to linear acceleration, as rotational varied less between models. At the temporal location, shell thickness, vent configuration, and radius of curvature were found to influence helmet effective stiffness. This should be optimized to reduce impact kinematics. At the frontal, helmet rim location, liner thickness tapered off for some helmets, likely due to lack of standards testing at this location. This is a frequently impacted location for cyclists, suggesting that the standards testable area should be expanded to include the rim. These results can inform manufacturers, standards bodies, and consumers alike, aiding the development of improved bicycle helmet safety.