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D.S. Young

University of Hong Kong

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Publication

Featured researches published by D.S. Young.

Cancer Research | 2005

Three unique antibodies demonstrate therapeutic effects against CD63, a novel target for cancer therapy

Susan E. Hahn; Victor Saldivia; Daad Sayegh; Huma Ahmad; Lisa M. Cechetto; Luis da Cruz; D.S. Young

Journal of Clinical Oncology | 2008

Human chimeric anti-CD44 antibody ARH460–16–2 binds leukemic cells and malignant plasma cells

T. Guillaume; N. Robillard; H. Avet-Loiseau; J. Delaunay; J. L. Harousseau; Susan Hahn; L. A. da Cruz; Daniel S. Pereira; D. B. Rubinstein; D.S. Young

Journal of Clinical Oncology | 2008

Clinical development of huARH460-16-2: A therapeutic antibody targeting the CD44 cancer stem cell antigen on high-incidence adenocarcinomas

Susan Hahn; L. A. da Cruz; Ashwani K. Gupta; B.C. Mak; L. Popp; Daniel S. Pereira; D. B. Rubinstein; D.S. Young

Ejc Supplements | 2008

521 POSTER A monoclonal antibody targeting the breast cancer stem cell marker melanoma-associated chondroitin sulfate proteoglycan improves survival and demonstrates anti-tumor activity in vivo

Ashwani K. Gupta; Alison L. Ferry; Mitra Amoozgar; Carlos Alexandre Vieira; Daad Sayegh; J. Menendez; N. Ceric; L.A.G. da Cruz; Daniel S. Pereira; D.S. Young

Ejc Supplements | 2008

517 POSTER A monoclonal antibody (AR36A36.11.1) with potent in vivo efficacy in multiple human cancer models targets CD59

B. Mak; F. McConkey; N. Feng; K. O'Reilly; S.W. Fung; M. Wang; S. Chau; S.E. Hahn; D.S. Pereira; D.S. Young

Ejc Supplements | 2008

371 POSTER Toxicology and pharmacokinetics of humanized AR47A6.4.2, the first unconjugated therapeutic monoclonal antibody targeting TROP-2

N. Chouinard; Susan Hahn; A.H.L. Truong; L. Popp; X. Wang; D. Sayegh; V. Harris; B.C. Mak; D.B. Rubinstein; D.S. Young

Ejc Supplements | 2008

538 POSTER ARH460-16-2, targeting the CD44 cancer stem cell marker, uses multiple mechanisms to achieve its therapeutic anti-cancer effects

L.A.G. da Cruz; K. O'Reilly; Fortunata McConkey; X.W. Wang; T. Antoshchenko; N. Aziz; Ashwani K. Gupta; Susan Hahn; Daniel S. Pereira; D.S. Young

Ejc Supplements | 2008

543 POSTER Location… location… location: hitting the functional epitope within the target is essential for anti-cancer antibody therapeutics

B.C. Mak; A.H.L. Truong; Ningping Feng; L.A.G. da Cruz; B.S. Mistry; Sui-Wah Fung; T. Perez; Susan Hahn; Daniel S. Pereira; D.S. Young

Molecular Cancer Therapeutics | 2007

Chimeric and humanized versions of the anti-CD44 monoclonal antibody ARH460-16-2 have potent anti-tumor efficacy in established models of human breast and metastatic liver cancer

Luis da Cruz; Ningping Feng; Terence Lee; Daad Sayegh; Baldwin Mak; Ming Wang; Mitra Amoozgar; Susan Hahn; Daniel Pereira; Helen Findlay; D.S. Young

ASCO Meeting Abstracts | 2007

Therapeutic monoclonal antibodies target phenotypically-differing human breast cancer

Susan Hahn; L. A. da Cruz; Daad Sayegh; Alison L. Ferry; K. O'Reilly; Daniel S. Pereira; D. B. Rubinstein; Helen P. Findlay; D.S. Young

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Collaboration

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Lisa M. Cechetto

Hoffmann-La Roche

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Susan E. Hahn

Hoffmann-La Roche

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Susan Hahn

Ipsen

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Daniel S. Pereira

Astellas Pharma

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Daad Sayegh

University of Hong Kong

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Ashwani K. Gupta

University Health Network

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Alison L. Ferry

Hoffmann-La Roche

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Luis da Cruz

University of Hong Kong

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Mitra Amoozgar

University of Hong Kong

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Fortunata McConkey

Ipsen

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