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Daniel M. Solomon

Schering-Plough

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Publication

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Bioorganic & Medicinal Chemistry Letters | 2002

The synthesis of substituted fluorenes as novel non-imidazole histamine H3 inhibitors

Pauline C. Ting; Joe F. Lee; Margaret M. Albanese; Wing C. Tom; Daniel M. Solomon; Robert G. Aslanian; Neng-Yang Shih; Robert E. West

A novel non-imidazole fluorene oxime 1a has been identified as a histamine H(3) inhibitor, and its structure-activity relationship has been evaluated.

Bioorganic & Medicinal Chemistry Letters | 1995

Synthesis of dibenzo[a,d]cycloheptanes as cytokine biosynthesis inhibitors

Pauline C. Ting; Joe F. Lee; Daniel M. Solomon; Sidney R. Smith; Carol Terminelli; James Jakway; Demetris N. Zambas

Abstract 2-[10,11-Dihydro-5-ethoxy-5 H -dibenzo[a,d]cyclohepten-5-yl]-N,N-dimethyl-ethanamine (1) has been found to possess anticytokine activity. The synthesis and structure-activity relationship study of a series of analogues are reported.

Journal of Medicinal Chemistry | 1985

Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines

James J. Kaminski; James A. Bristol; Chester Puchalski; Raymond G. Lovey; Arthur J. Elliott; Henry Guzik; Daniel M. Solomon; David J. Conn; Martin S. Domalski

Journal of Medicinal Chemistry | 1989

Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogues.

James J. Kaminski; Chester Puchalski; Daniel M. Solomon; Rizvi Rk; David J. Conn; Arthur J. Elliott; Raymond G. Lovey; Henry Guzik; Peter J.S. Chiu; James F. Long

Journal of Medicinal Chemistry | 1987

Antiulcer agents. 2. Gastric antisecretory, cytoprotective, and metabolic properties of substituted imidazo[1,2-a]pyridines and analogues.

James J. Kaminski; Hilbert Jm; Pramanik Bn; Daniel M. Solomon; David J. Conn; Rizvi Rk; Arthur J. Elliott; Henry Guzik; Raymond G. Lovey; Domalski Ms

Archive | 2006

Phenoxypiperidines and analogs thereof useful as histamine h3 antagonists

Mwangi W. Mutahi; Robert G. Aslanian; Michael Y. Berlin; Christopher W. Boyce; Manuel de Lera Ruiz; Kevin D. Mccormick; Daniel M. Solomon; Henry A. Vaccaro; Junying Zheng; Purakkattle J. Biju; Younong Yu; Wei Zhou; Xiaohong Zhu

Journal of Medicinal Chemistry | 1987

Antiulcer agents. 3. Structure-activity-toxicity relationships of substituted imidazo[1,2-a]pyridines and a related imidazo[1,2-a]pyrazine.

James J. Kaminski; D. G. Perkins; J. D. Frantz; Daniel M. Solomon; Arthur J. Elliott; Peter J.S. Chiu; James F. Long

Archive | 2006

Substituted aniline derivatives useful as histamine h3 antagonists

Daniel M. Solomon; Robert G. Aslanian; Michael Y. Berlin; Manuel de Lera Ruiz; Kevin D. Mccormick; Mwangi W. Mutahi; Wing C. Tom

Archive | 2003

(1-4-piperidinyl) benzimidazole derivatives useful as histamine h3 antagonists

Qingbei Zeng; Robert G. Aslanian; Michael Y. Berlin; Christopher W. Boyce; Jianhua Cao; Joseph A. Kozlowski; Pietro Mangiaracina; Cormick Kevin D. Mc; Mwangi W. Mutahi; Stuart B. Rosenblum; Neng-Yang Shih; Daniel M. Solomon; Wing C. Tom

Archive | 2003

Benzimidazole derivatives useful as histamine H3 antagonists

Qingbei Zeng; Robert G. Aslanian; Michael Y. Berlin; Christopher W. Boyce; Jianhua Cao; Joseph A. Kozlowski; Pietro Mangiaracina; Kevin D. Mccormick; Mwangi W. Mutahi; Stuart B. Rosenblum; Neng-Yang Shih; Daniel M. Solomon; Wing C. Tom

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Collaboration

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Robert G. Aslanian

Schering-Plough

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Wing C. Tom

Schering-Plough

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Michael Y. Berlin

Schering-Plough

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Mwangi W. Mutahi

Schering-Plough

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Neng-Yang Shih

Schering-Plough

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James J. Kaminski

University of Kansas

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Stuart B. Rosenblum

Schering-Plough

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Christopher W. Boyce

Schering-Plough

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Pauline C. Ting

Schering-Plough

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Kevin D. Mccormick

Schering-Plough

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