James J. Kaminski | Researchain

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Tetrahedron | 1976

3-Bromo-4,4-dimethyl-2-oxazolidinone: Preparation and investigation of a new brominating agent☆

James J. Kaminski; Nicolae S. Bodor

Abstract A new brominating agent, 3-bromo-4,4-dimethyl-2-oxazolidinone (NBDMO) was prepared and its reactions compared to that of N-bromosuccinimide (NBS). NBDMO was found to have a lower “bromine potential” relative to NBS and, consequently possesses a less polar N-bromine bond. NBDMO was found to be equivalent or better than NBS as a brominating and oxidizing agent in the reactions investigated.

Journal of Medicinal Chemistry | 1980

Soft drugs. 1. Labile quaternary ammonium salts as soft antimicrobials

Nicholas Bodor; James J. Kaminski; Sally Selk

Journal of Medicinal Chemistry | 1997

Antiulcer agents. 6. Analysis of the in vitro biochemical and in vivo gastric antisecretory activity of substituted imidazo[1,2-a]pyridines and related analogues using comparative molecular field analysis and hypothetical active site lattice methodologies.

James J. Kaminski; Arthur M. Doweyko

Journal of Medicinal Chemistry | 1985

Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines

James J. Kaminski; James A. Bristol; Chester Puchalski; Raymond G. Lovey; Arthur J. Elliott; Henry Guzik; Daniel M. Solomon; David J. Conn; Martin S. Domalski

Journal of Medicinal Chemistry | 1991

Antiulcer agents. 5. Inhibition of gastric H+/K(+)-ATPase by substituted imidazo[1,2-a]pyridines and related analogues and its implication in modeling the high affinity potassium ion binding site of the gastric proton pump enzyme.

James J. Kaminski; Björn Wallmark; Carin Briving; Britt Marie Andersson

Journal of the American Chemical Society | 2002

The Active Site of a Zinc-Dependent Metalloproteinase Influences the Computed pKa of Ligands Coordinated to the Catalytic Zinc Ion

Jason B. Cross; Jose S. Duca; James J. Kaminski; Vincent S. Madison

Journal of Medicinal Chemistry | 1989

Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogues.

James J. Kaminski; Chester Puchalski; Daniel M. Solomon; Rizvi Rk; David J. Conn; Arthur J. Elliott; Raymond G. Lovey; Henry Guzik; Peter J.S. Chiu; James F. Long

Journal of Medicinal Chemistry | 1987