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Dariusz Wodka

Millennium Pharmaceuticals

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Publication

Featured researches published by Dariusz Wodka.

Journal of Medicinal Chemistry | 2005

Identification of 2-(4-benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an orally efficacious melanin-concentrating hormone receptor 1 antagonist for the treatment of obesity.

Andrew J. Souers; Ju Gao; Michael E. Brune; Eugene N. Bush; Dariusz Wodka; Anil Vasudevan; Andrew S. Judd; Mathew M. Mulhern; Sevan Brodjian; Brian D. Dayton; Robin Shapiro; Lisa E. Hernandez; Kennan C. Marsh; Hing L. Sham; Christine A. Collins; Philip R. Kym

Journal of Medicinal Chemistry | 2007

Discovery and Metabolic Stabilization of Potent and Selective 2-Amino-N-(adamant-2-yl) Acetamide 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors

Jeffrey J. Rohde; Marina A. Pliushchev; Bryan K. Sorensen; Dariusz Wodka; Qi Shuai; Jiahong Wang; Steven Fung; Katina Monzon; William J. Chiou; Liping Pan; Xiaoqing Deng; Linda E. Chovan; Atul Ramaiya; Mark M. Mullally; Rodger F. Henry; DeAnne Stolarik; Hovis M. Imade; Kennan C. Marsh; David W. A. Beno; Thomas A. Fey; Brian A. Droz; Michael E. Brune; Heidi S. Camp; Hing L. Sham; Ernst U. Frevert; Peer B. Jacobson; James T. Link

Archive | 2003

Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor

Andrew J. Souers; Christine A. Collins; Ju Gao; Andrew S. Judd; Philip R. Kym; Mathew M. Mulhern; Hing L. Sham; Dariusz Wodka

Archive | 2008

Treatment of central nervous system disorders

R. Scott Bitner; Kaitlin E. Browman; Michael E. Brune; Yixian Chen; Jurgen Dinges; Karla Drescher; Peer B. Jacobson; Hwan-Soo Jae; Ravi Kurukulasuriya; James T. Link; David J. Madar; Jyoti R. Patel; Marina A. Pliushchev; Jeffrey J. Rohde; Lynne E. Rueter; Qi Shuai; Bryan K. Sorensen; Jiahong Wang; Karsten Wicke; Martin Winn; Dariusz Wodka; Vince Yeh; Hong Yong

Journal of Medicinal Chemistry | 2005

Discovery and Characterization of Aminopiperidinecoumarin Melanin Concentrating Hormone Receptor 1 Antagonists

Philip R. Kym; Rajesh R. Iyengar; Andrew J. Souers; John K. Lynch; Andrew S. Judd; Ju Gao; Jennifer L. Freeman; Mathew M. Mulhern; Gang Zhao; Anil Vasudevan; Dariusz Wodka; Christopher Blackburn; James Brown; Jennifer Lee Che; Courtney Cullis; Su Jen Lai; Tom Marsilje; Jon Roses; Todd B. Sells; Brad J. Geddes; Elizabeth Govek; Michael A. Patane; Dennis G. Fry; Brian D. Dayton; Sevan Brodjian; Doug H. Falls; Michael E. Brune; Eugene N. Bush; Robin Shapiro; Victoria Knourek-Segel

Bioorganic & Medicinal Chemistry Letters | 2004

Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1

Andrew J. Souers; Dariusz Wodka; Ju Gao; Jared C. Lewis; Anil Vasudevan; Robert G. Gentles; Sevan Brodjian; Brian D. Dayton; Christopher A. Ogiela; Dennis G. Fry; Lisa E. Hernandez; Kennan C. Marsh; Christine A. Collins; Philip R. Kym

Journal of Medicinal Chemistry | 2006

Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety.

John K. Lynch; Jennifer C. Freeman; Andrew S. Judd; Rajesh R. Iyengar; Mathew M. Mulhern; Gang Zhao; James J. Napier; Dariusz Wodka; Sevan Brodjian; Brian D. Dayton; Doug H. Falls; Ogiela C; Regina M. Reilly; Thomas J. Campbell; James S. Polakowski; Lisa E. Hernandez; Kennan C. Marsh; Robin Shapiro; Knourek-Segel; Brian A. Droz; Eugene N. Bush; Michael E. Brune; Lee C. Preusser; Ryan M. Fryer; Glenn A. Reinhart; Houseman K; Gilbert Diaz; Mikhail A; Limberis Jt; Hing L. Sham

Bioorganic & Medicinal Chemistry Letters | 2005

Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.

Andrew J. Souers; Ju Gao; Dariusz Wodka; Andrew S. Judd; Mathew M. Mulhern; James J. Napier; Michael E. Brune; Eugene N. Bush; Sevan Brodjian; Brian D. Dayton; Robin Shapiro; Lisa E. Hernandez; Kennan C. Marsh; Hing L. Sham; Christine A. Collins; Philip R. Kym

Archive | 2003

Antagonists of melanin concentrating hormone receptor

Christopher Blackburn; Sujen Lai; Jennifer Lee Che; Martin P. Maguire; Michael A. Patane; Courtney Cullis; James Brown; Anil Vasudevan; Jennifer C. Freeman; Mathew M. Mulhern; John K. Lynch; Ju Gao; Dariusz Wodka; Andrew J. Souers; Rajesh R. Iyengar; Mary K. Verzal; Philip R. Kym

Archive | 2003

2-Aminoquinolines as melanin concentrating hormone receptor antagonists

Christine A. Collins; Ju Gao; Philip R. Kym; Jared C. Lewis; Andrew J. Souers; Anil Vasudevan; Dariusz Wodka

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Collaboration

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Andrew J. Souers

University of California

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Ju Gao

Millennium Pharmaceuticals

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Mathew M. Mulhern

Millennium Pharmaceuticals

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Philip R. Kym

University of Texas at Austin

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Andrew S. Judd

University of Texas at Austin

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Christine A. Collins

Northwestern University

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Hing L. Sham

Thermo Fisher Scientific

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Anil Vasudevan

Duquesne University

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John K. Lynch

Millennium Pharmaceuticals

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Kennan C. Marsh

University of California

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