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Featured researches published by David G. Martin.


Recent results in cancer research | 1978

Detection and assay of antitumor antibiotics.

Ladislav J. Hanka; Sandra L. Kuentzel; David G. Martin; P. F. Wiley; Gary L. Neil

Cell culture techniques and antimicrobial systems can be used as detection systems for new antibiotic structures. Antimicrobial systems by virtue of their speed, economy, ease of use, and adaptation to chromatographic (bioautographic) techniques are definitely superior for assay and for dereplication purposes. A prescreen assay system which combines the advantages and minimizes the disadvantages of the two approaches is described.


Archive | 1977

Composition of matter and process

Ladislav J. Hanka; David G. Martin


The Journal of Antibiotics | 1978

CC-1065 (NSC-298223), A NEW ANTITUMOR ANTIBIOTIC

Ladislav J. Hanka; A. Dietz; S. A. Gerpheide; Sandra L. Kuentzel; David G. Martin


The Journal of Antibiotics | 1981

CC-1065 (NSC 298223), a potent new antitumor agent improved production and isolation, characterization and antitumor activity.

David G. Martin; Carolyn Biles; Shirley A. Gerpheide; Ladislav J. Hanka; William C. Krueger; J. Patrick McGovren; S. A. Mizsak; Gary L. Neil; Julianna Stewart; Jeronimo Visser


The Journal of Antibiotics | 1980

Structure of CC-1065 (NSC-298223), a new antitumor antibiotic.

David G. Martin; Connie G. Chidester; D. J. Duchamp; S. A. Mizsak


The Journal of Antibiotics | 1975

Structure of quinomycin antibiotics.

David G. Martin; S. A. Mizsak; C. Biles; Julianna Stewart; L. Baczynskyj; P. A. Meulman


The Journal of Antibiotics | 1975

THE ISOLATION, STRUCTURE, AND ABSOLUTE CONFIGURATION OF U- 43.795, A NEW ANTITUMOR AGENT

David G. Martin; Connie G. Chidester; S. A. Mizsak; D. J. Duchamp; L. Baczynskyj; William C. Krueger; R. J. Wnuk; P. A. Meulman


The Journal of Antibiotics | 1985

CC-1065 transformations.

David G. Martin; S. A. Mizsak; William C. Krueger


The Journal of Antibiotics | 1986

Preparative resolution of an actinomycin complex by countercurrent chromatography in the Ito coil planet centrifuge

David G. Martin; Randy E. Peltonen; James W. Nielsen


Archive | 1975

Process for production of AT-125

Ladislav J. Hanka; David G. Martin

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