Ladislav J. Hanka | Researchain

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Featured researches published by Ladislav J. Hanka.

Recent results in cancer research | 1978

Detection and assay of antitumor antibiotics.

Ladislav J. Hanka; Sandra L. Kuentzel; David G. Martin; P. F. Wiley; Gary L. Neil

Cell culture techniques and antimicrobial systems can be used as detection systems for new antibiotic structures. Antimicrobial systems by virtue of their speed, economy, ease of use, and adaptation to chromatographic (bioautographic) techniques are definitely superior for assay and for dereplication purposes. A prescreen assay system which combines the advantages and minimizes the disadvantages of the two approaches is described.

Archive | 1977

Composition of matter and process

Ladislav J. Hanka; David G. Martin

The Journal of Antibiotics | 1978

CC-1065 (NSC-298223), A NEW ANTITUMOR ANTIBIOTIC

Ladislav J. Hanka; A. Dietz; S. A. Gerpheide; Sandra L. Kuentzel; David G. Martin

The Journal of Antibiotics | 1981

CC-1065 (NSC 298223), a potent new antitumor agent improved production and isolation, characterization and antitumor activity.

David G. Martin; Carolyn Biles; Shirley A. Gerpheide; Ladislav J. Hanka; William C. Krueger; J. Patrick McGovren; S. A. Mizsak; Gary L. Neil; Julianna Stewart; Jeronimo Visser

Fems Microbiology Letters | 1985