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David L. McLeod

University of Toronto

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Featured researches published by David L. McLeod.

Archive | 1978

Culture Systems In Vitro for the Assay of Erythrocytic and Megakaryocytic Progenitors

David L. McLeod; Mona M. Shreeve; Arthur A. Axelrad

The production of erythrocytic colonies from murine fetal liver cells seeded in semisolid plasma culture medium was first accomplished in 1971.1 The plasma culture system was then improved2 and is now widely used along with the methylcellulose system3 for the assay of the erythropoietic progenitors, CFU-e and BFU-e, of adult as well as fetal hemopoietic tissues of several species including man.

Proceedings of the National Academy of Sciences of the United States of America | 1971

Induction of colonies of hemoglobin-synthesizing cells by erythropoietin in vitro.

John R. Stephenson; Arthur A. Axelrad; David L. McLeod; Mona M. Shreeve

Blood | 1974

Improved Plasma Culture System for Production of Erythrocytic Colonies In Vitro: Quantitative Assay Method for CFU-E

David L. McLeod; Mona M. Shreeve; Arthur A. Axelrad

Nature | 1976

Induction of megakaryocyte colonies with platelet formation in vitro.

David L. McLeod; Mona M. Shreeve; Arthur A. Axelrad

Blood | 1976

Separation of the erythropoietin-responsive progenitors BFU-E and CFU-E in mouse bone marrow by unit gravity sedimentation

Ds Heath; Arthur A. Axelrad; David L. McLeod; Mona M. Shreeve

Blood | 1980

Chromosome Marker Evidence for the Bipotentiality of BFU-E

David L. McLeod; Mona M. Shreeve; Arthur A. Axelrad

Journal of Cellular Physiology | 1986

Interleukin 3 and cell cycle progression

David J. Kelvin; Susan Chance; Mona M. Shreeve; Arthur A. Axelrad; Joe A. Connolly; David L. McLeod

Proceedings of the National Academy of Sciences of the United States of America | 1975

Erythroid colony induction without erythropoietin by Friend leukemia virus in vitro.

B J Clarke; Arthur A. Axelrad; Mona M. Shreeve; David L. McLeod

Journal of Cellular Physiology | 1989

Interleukin 3‐stimulated proliferation is sensitive to pertussis toxin: Evidence for a guanyl nucleotide regulatory protein‐mediated signal transduction mechanism

David J. Kelvin; Mona M. Shreeve; C. McAuley; David L. McLeod; Gilles Simard; Joe A. Connolly

Journal of Cellular Physiology | 1985

A self‐renewing, bipotential erythroid/mast cell progenitor in continuous cultures of normal murine bone marrow

Françoise Wendling; Mona M. Shreeve; David L. McLeod; Arthur A. Axelrad

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Arthur A. Axelrad

University of Toronto

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Mona M. Shreeve

University of Toronto

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David J. Kelvin

University Health Network

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Françoise Wendling

University of Toronto

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Joe A. Connolly

University of Toronto

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John R. Stephenson

University of Toronto

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C. McAuley

University of Toronto

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Gilles Simard

University of Toronto

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Susan Chance

University of Toronto

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