David Sollars

Safety review of kava (Piper methysticum) by the Natural Standard Research Collaboration.

This systematic review discusses the proposed uses, dosing parameters, adverse effects, toxicology, interactions and mechanism of action of kava. The widespread concern regarding the potential hepatotoxicity of kava is discussed. A recommendation is made to consolidate and analyse available reports and to continue postmarket surveillance in an international repository to prevent duplicates and promote collection of thorough details at the time of each report so that any association with kava is clearly defined.

An Evidence-Based Systematic Review of Aloe vera by the Natural Standard Research Collaboration

An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

Fenugreek (Trigonella foenum-graecum L. Leguminosae): An Evidence-Based Systematic Review by the Natural Standard Research Collaboration

An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology and dosing. doi:10.1300/J157v07n03_06 [Article copies available for a fee from The Haworth Document Delivery Service: 1–800-HAWORTH. E-mail address: <docdelivery@haworthpress.com> Website: <http://www.HaworthPress.com>]

Boswellia: An Evidence-Based Systematic Review by the Natural Standard Research Collaboration

An evidence-based systematic review including written and statistical analysis of scientific literature, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

Horse chestnut:a multidisciplinary clinical review.

Horse chestnut seed extract (HCSE) is widely used in Europe for the management of chronic venous insufficiency (CVI). Although traditionally recommended for a variety of medical conditions, CVI is the only indication for which there is strong supportive scientific evidence. Review of the literature reveals 14 randomized controlled trials, of which seven are methodologically of high quality, albeit limited by small sample sizes and short durations. These studies support the superiority of HCSE over placebo, and suggest equivalence to compression stockings and to oral oxerutins. In the future, a longer and adequately powered randomized trial is warranted to compare HCSE to standard of care, and to further assess safety and long-term efficacy. There are no data to suggest that horse chestnut flower, raw seed, branch bark, or leaf are effective for any indication, and it is recommended that these products not be used, as they are known to be toxic when ingested.

Chaparral Monograph: A Clinical Decision Support Tool

An evidence-based systematic review including scientific evidence, expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing.

Kava monograph: a clinical decision support tool.

The proposed uses, dosing parameters, adverse effects, toxicology, interactions and mechanism of action of kava is systematically reviewed in monograph format.

Natural standard professional monograph

-methoxy-4-(2-propenyl)-phenol, Caryophylli atheroleum, Caryophylli Flos, caryophyllum, caryophyllus, Caryophyllus aromaticus, cengke, cengkeh, chiodo di garofano (Italian), choji, chor boghbojh, chor poghpch, cinnamon nails, clau, clavos, clou de girofle, Clous de Girolfe (French), clovas de comer, clove bud, clove bud oil, clove cigarettes, clove essential oil, clove leaf, craveiro da india, cravinho, cravo, cravo de olor, cuisoare, ding heung, ding xiang, dinh huong, dok chan, dried clove, Eugenia aromatica, Eugenia bud, Eugenia caryophyllata, Eugenia caryophyllus, faranfil, Flores Caryophylli, gahn plu, garifalo, garifallo, garifano, garn ploo, Gewurznelken Nagelein (German), gozdzik, gozdzikow korzenny, graambu, ground clove, gvazdikelia, gvozdika, harilik nelgipuu, hrebicek, iltze kanela, jeonghyang, jeonghyong namu, jonghyang, kabsh qarunfil, kala, kalmpir, kan phou, kan phu, karafuu, karamfil, kariofilla, kariofilo, khan pluu, khlam puu, klabong pako, klincic, klinceky, klincki, krambu, kreteks, krinfud, kruidnagel, krustnaglinas, kryddnejlikor, kryddernellike, kullobu, kurobu, kvapnusis gvazdikmedis, labanga, labango, laung, lavang, lavanga, lavangalu, lavnagamu, lay hnyin, leoung, ley nyim bwint, mikhak, mikhaki, mixaki, moschokarfi, Myrtaceae (family), nageljnove zbice, nagri, negull, neilikka, nejlikor, nelk, nelke, nellik, nellike, oil of clove, oleum caryophylli, pentogen (clove oil), qalampir, shriisanjnan, Syzigium aromaricum (L) Merr. and Perry., szegfu, szegfuszeg, tropical myrtle, tsiporen.

An evidence-based systematic review of passion flower (Passiflora Incarnata L.) by the natural standard research collaboration

Authors/Editors: Catherine Ulbricht, PharmD, MBA[c] (Massachusetts General Hospital); Ethan Basch, MD (Memorial Sloan-Kettering Cancer Center); Heather Boon, BScPhm, PhD, (University of Toronto); Kelly Dowhower Karpa, PhD, RPh (Pennsylvania State University); Gerald Gianutsos, PhD, JD (University of Connecticut); Katie Nummy, BS (Northeastern University); Erica Seamon, PharmD (Natural Standard Research Collaboration); Michael Smith, MRPharmS, ND (Canadian College of Naturopathic Medicine); David Sollars MAc, HMC (New England School of Acupuncture); Shaina Tanguay-Colucci, BS (Natural Standard Research Collaboration); Minney Varghese, BS (Northeastern University); Wendy Weissner, BA (Natural Standard Research Collaboration); Jen Woods, BS (Natural Standard Research Collaboration). Blinded Peer-Review: Natural Standard Editorial Board.