Debora Vansteenwegen

Affect 4.0: A free software package for implementing psychological and psychophysiological experiments

We describe Affect 4.0, a user-friendly software package for implementing psychological and psychophysiological experiments. Affect 4.0 can be used to present visual, acoustic, and/or tactile stimuli in highly complex (i.e., semirandomized and response-contingent) sequences. Affect 4.0 is capable of registering response latencies and analog behavioral input with millisecond accuracy. Affect 4.0 is available free of charge.

Fear and Learning: From Basic Processes to Clinical Implications

This book brings together the most recent empirical developments in learning theory for understanding the etiology and treatment of fears and phobias. The editors have assembled contributions from leading scientists whose work represents the cutting edge in such areas as measurement methodology, neurobiology, cognitive processing, behavioral models, emotion regulation, and pharmacological and other clinical treatments. After a review of the history of fear learning and basic concepts and methods in fear measurement, subsequent chapters elucidate processes of acquisition and maintenance of fear, finally moving to the extinction, renewal, and reinstatement of fear. The research synthesized in this book has applicability to the entire spectrum of anxiety disorders, including obsessive-compulsive disorder, social anxiety disorder, and specific phobias.

Dissociable Roles for the Hippocampus and the Amygdala in Human Cued versus Context Fear Conditioning

Lesion studies in animals have identified a critical role of the hippocampus in context fear conditioning. To extend these findings to human volunteers, we used functional magnetic resonance imaging to investigate neural responses associated with context fear conditioning in humans. Our novel conditioning paradigm consisted of aversive electrical shocks (unconditioned stimulus) that were delivered either cue or context related. Differential evoked responses, related to the conditioned stimulus (CS), were found in the anterior cingulate cortex and the bilateral insular cortices, regions that have been implicated in anticipatory anxiety. In case of context conditioning, a similar pattern was observed during the presentation of the entire context. In line with previous conditioning studies, differential responses in the amygdala showed a time by stimulus interaction, suggesting rapid adaptation of CS-specific responses. More importantly, a similar differential decay of activation was observed during context conditioning in the hippocampus, in agreement with a role of the hippocampus in the acquisition phase of human context fear conditioning.

EYE MOVEMENT REGISTRATION AS A CONTINUOUS INDEX OF ATTENTION DEPLOYMENT : DATA FROM A GROUP OF SPIDER ANXIOUS STUDENTS

In the last fifteen years, there has been an explosion in the application of experimental cognitive paradigms within the research on emotional disorders. One of the most fruitful lines of research in this area is the study of selective attention in persons suffering from an emotional disorder. Several paradigms have been employed to examine this attentional bias (e.g. dichotic listening, Emotional Stroop, visual dot-probe task) and to demonstrate how task performance is facilitated or inhibited due to the presentation of a stimulus that is related to the emotional concerns of the participants. A problem associated with these paradigms is that they only measure attention deployment at a very specific moment immediately after the presentation of the emotional stimulus, but are not suitable for capturing the course of selective attention over longer time periods. In a study with spider anxious participants, we used on-line registration of eye movements as a continuous index of attention deployment towards em...

Expectancy-learning and evaluative learning in human classical conditioning: affective priming as an indirect and unobtrusive measure of conditioned stimulus valence.

It has been argued that in classical conditioning two processes might be operative. First, one may learn that the conditioned stimulus (CS+) is a valid predictor for the occurrence of the biologically negative or positive event (US; expectancy-learning). Second, one may learn to perceive the conditioned stimulus itself as a negative or positive stimulus, depending on the valence of the event it has been associated with (evaluative learning). Until the present, however, both forms of learning have been investigated using rather different conditioning procedures. Using a differential aversive conditioning preparation with pictures of human faces as CSs and an electrocutaneous stimulus as US, we were able to demonstrate that both forms of learning can co-occur. Moreover, the extent of evaluative learning in this aversive conditioning procedure did not significantly differ from the amount of evaluative learning in an evaluative conditioning procedure with positive and negative adjectives as USs, which was administered to the same participants. In the present study evaluative learning was not only indexed by direct evaluative ratings, but we introduced affective priming as an indirect and unobtrusive, reaction time based measure of stimulus valence. Finally, imagery instructions during acquisition did not facilitate expectancy-learning nor evaluative learning.

The acquisition of fear of movement-related pain and associative learning: a novel pain-relevant human fear conditioning paradigm.

Summary A novel pain‐relevant fear conditioning paradigm that demonstrates the involvement of associative learning in the acquisition of fear of movement‐related pain. ABSTRACT Current fear‐avoidance models consider fear of pain as a key factor in the development of chronic musculoskeletal pain. Generally, the idea is that by virtue of the formation of associations or acquired propositional knowledge about the relation between neutral movements and pain, these movements may signal pain, and hence start to elicit defensive fear responses (eg, avoidance behavior). This assumption has never been investigated experimentally. Therefore, we developed a pain‐relevant fear conditioning paradigm using a movement as a conditioned stimulus (CS) and a painful electrocutaneous stimulus as an unconditioned stimulus (US) to examine the acquisition of fear of movement‐related pain in healthy subjects. In a within‐subjects design, participants manipulated a joystick to the left/right in the experimental (predictable) condition, and upward/downward in the control (unpredictable) condition or vice versa. In the predictable condition, one movement direction (CS+), and not the other (CS−), was followed by painful stimuli. In the unpredictable condition, painful stimuli were always delivered during the intertrial interval. Both fear of movement‐related pain ratings and eyeblink startle measures were more elevated in response to the CS+ than to the CS−, whereas no differences occurred between both unreinforced CSs in the control condition. Participants were slower initiating a CS+ movement than a CS− movement, while response latencies to CSs in the control condition did not differ. These data support the acquisition of fear of movement‐related pain by associative learning. Results are discussed in the broader context of the acquisition of pain‐related fear in patients with musculoskeletal pain.

Resistance to extinction in evaluative conditioning

A well-demonstrated phenomenon in traditional Pavlovian conditioning research with humans is that of experimental extinction. In contrast, human evaluative conditioning research suggests that evaluative learning shows marked resistance to extinction. Here, the authors replicate both findings concurrently. Two differential fear conditioning experiments with an electrocutaneous stimulus as the unconditioned stimulus evidenced (a) sensitivity to extinction using an autonomic skin-conductance measure and (b) complete resistance to extinction using an affective-priming measure. The results corroborate the idea that evaluative conditioning is more resistant to extinction than is expectancy learning (F. Baeyens, P. Eelen, & G. Crombez, 1995).

Exposure to physical movements in low back pain patients: Restricted effects of generalization

Whether the effects of exposure to 1 movement generalize to another dissimilar movement was investigated in 37 patients with low back pain (15 men, 22 women). Two movements were executed twice: bending forward while standing and lifting 1 leg while lying down. During each trial, baseline pain, expected pain, and experienced pain were recorded. Similar ratings for perceived harm were obtained. Analyses revealed an initial over prediction of pain, but after exposure the overprediction was readily corrected. This exposure effect did not generalize toward another dissimilar movement. These results were only characteristic for patients with catastrophic thinking about pain. Low pain catastrophizers did not overpredict pain. There were no effects of exposure on perceived harm. Exposure may profitably be conceived of as the learning of exceptions to a general rule.

Exposure to physical movement in chronic back pain patients: no evidence for generalization across different movements.

This study investigated whether the effects of exposure to one movement generalize towards another dissimilar movement in patients with low back pain. Thirty-nine patients (11 male, 28 female; mean age=43.49 yrs) were requested to perform two movements twice, i.e. bending forward and straight leg raising. During each of the four trials, baseline pain, expected pain and experienced pain were recorded. Analyses revealed that patients initially overpredicted pain, but after exposure the overprediction was readily corrected. This exposure effect did not generalize towards another dissimilar movement. The above pattern of results was only characteristic for patients reporting a high frequency of catastrophic thinking about pain. Low pain catastrophizers did not overpredict pain. The results are discussed in terms of the view that exposure may be better conceived of as the learning of exceptions to a general rule.

Feeling we're biased: Autonomic arousal and reasoning conflict

Human reasoning is often biased by intuitive beliefs. A key question is whether the bias results from a failure to detect that the intuitions conflict with logical considerations or from a failure to discard these tempting intuitions. The present study addressed this unresolved debate by focusing on conflict-related autonomic nervous system modulation during biased reasoning. Participants’ skin conductance responses (SCRs) were monitored while they solved classic syllogisms in which a cued intuitive response could be inconsistent or consistent with the logical correct response. Results indicated that all reasoners showed increased SCRs when solving the inconsistent conflict problems. Experiment 2 validated that this autonomic arousal boost was absent when people were not engaged in an active reasoning task. The presence of a clear autonomic conflict response during reasoning lends credence to the idea that reasoners have a “gut” feeling that signals that their intuitive response is not logically warranted. Supplemental materials for this article may be downloaded from http://cabn.psychonomic-journals.org/content/supplemental.