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Dive into the research topics where Dirk Seidel is active.

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Featured researches published by Dirk Seidel.


Optometry and Vision Science | 2005

The effect of monocular and binocular viewing on the accommodation response to real targets in emmetropia and myopia.

Dirk Seidel; Lyle S. Gray; Gordon Heron

Purpose. Decreased blur-sensitivity found in myopia has been linked with reduced accommodation responses and myopigenesis. Although the mechanism for myopia progression remains unclear, it is commonly known that myopic patients rarely report near visual symptoms and are generally very sensitive to small changes in their distance prescription. This experiment investigated the effect of monocular and binocular viewing on static and dynamic accommodation in emmetropes and myopes for real targets to monitor whether inaccuracies in the myopic accommodation response are maintained when a full set of visual cues, including size and disparity, is available. Methods. Monocular and binocular steady-state accommodation responses were measured with a Canon R1 autorefractor for target vergences ranging from 0–5 D in emmetropes (EMM), late-onset myopes (LOM), and early-onset myopes (EOM). Dynamic closed-loop accommodation responses for a stationary target at 0.25 m and step stimuli of two different magnitudes were recorded for both monocular and binocular viewing. Results. All refractive groups showed similar accommodation stimulus response curves consistent with previously published data. Viewing a stationary near target monocularly, LOMs demonstrated slightly larger accommodation microfluctuations compared with EMMs and EOMs; however, this difference was absent under binocular viewing conditions. Dynamic accommodation step responses revealed significantly (p < 0.05) longer response times for the myopic subject groups for a number of step stimuli. No significant difference in either reaction time or the number of correct responses for a given number of step-vergence changes was found between the myopic groups and EMMs. Conclusion. When viewing real targets with size and disparity cues available, no significant differences in the accuracy of static and dynamic accommodation responses were found among EMM, EOM, and LOM. The results suggest that corrected myopes do not experience dioptric blur levels that are substantially different from emmetropes when they view free space targets.


Ophthalmic and Physiological Optics | 2006

Refractive group differences in accommodation microfluctuations with changing accommodation stimulus

Mhairi Day; Niall C. Strang; Dirk Seidel; Lyle S. Gray; Edward A. H. Mallen

Purpose:  Microfluctuations of accommodation are known to increase in magnitude with increasing accommodation stimulus. Reduced sensitivity to blur in myopic subjects could also lead to increases in the magnitude of the microfluctuations. The aim of this study is to examine the effect of variations in accommodation stimulus upon the microfluctuations in different refractive groups.


Vision Research | 2009

The effect of modulating ocular depth of focus upon accommodation microfluctuations in myopic and emmetropic subjects

Mhairi Day; Dirk Seidel; Lyle S. Gray; Niall C. Strang

The magnitude of accommodation microfluctuations increases in emmetropic subjects viewing low luminance targets or viewing a target through small artificial pupils. Larger microfluctuations reported in myopia may result from an abnormally large depth of focus (DoF). The effect of modulating the size of the DoF has not been investigated in myopic subjects and may help to explain the cause of the increased DoF. Accommodation microfluctuations were recorded under two experimental conditions. Firstly, 12 emmetropes (EMMs), and 24 myopes (MYOs) viewed a Maltese Cross target with luminance levels of 0.002, 0.2, 6 and 600cd/m(2) and in darkness, and second, 14 EMMs and 16 MYOs viewed a Maltese Cross target through pupil diameters of 0.5, 1, 2, 3, 4 and 5mm presented in Maxwellian view. The magnitude of the accommodation microfluctuations increased significantly with a target luminance of 0.002cd/m(2) (p<.03) and pinhole diameters of <2mm (p<.05). For all other luminance levels and pupil diameters the magnitude was constant. For both conditions, MYOs had significantly larger microfluctuations than EMMs (p<.01). Considerable inter-subject variability was observed in the degree to which the magnitude of the microfluctuations increased, for both the 0.002cd/m(2) luminance and 0.5mm pupils, however, this was not correlated with refractive error. The increase in the magnitude of the microfluctuations while viewing a low luminance target (0.002cd/m(2)) may be due to a shallower contrast gradient in the cortical image, with a consequent increase in DoF. The microfluctuations also increase when viewing through small pupils (<2mm), which increases the DoF without altering the contrast gradient. The larger microfluctuations found in the MYOs consolidates the theory that MYOs have a larger DoF than EMMs and therefore have a higher threshold for retinal image blur.


Journal of Vision | 2009

The relationship between object spatial profile and accommodation microfluctuations in emmetropes and myopes.

Mhairi Day; Lyle S. Gray; Dirk Seidel; Niall C. Strang

The accommodation microfluctuations are thought to be used by the accommodation controller to obtain information about the direction and magnitude of the required response by monitoring changes in the contrast gradient of this image. The contrast gradient can be altered by presenting different spatial frequency (SF) targets to the eye. Twelve myopes (MYOs) and 12 emmetropes (EMMs) viewed sine and square wave targets of SF 0.5, 1, 2, 4, 8, 16 cpd in a Badal optical system. Accommodation responses were recorded continuously using the Shin-Nippon SRW-5000 autorefractor. There is no change in magnitude of the accommodation microfluctuations as the SF of square waves is altered. While viewing sine wave targets, the microfluctuations are smallest for mid (2, 4 cpd) SFs and increase for low (0.5 cpd) and high (16 cpd) SFs. MYOs show a significantly larger increase in the microfluctuations for the 16 cpd target compared to the EMMs. MYOs have significantly larger microfluctuations than the EMMs throughout. The microfluctuations seem to be monitoring the contrast gradient of the cortical image, which is likely to be used by the accommodation control system during error detection. The results indicate that MYO subjects may have a shallower contrast gradient and the potential reasons and implications of this are discussed.


Investigative Ophthalmology & Visual Science | 2012

Image Jitter Enhances Visual Performance When Spatial Resolution Is Impaired

Lynne M. Watson; Niall C. Strang; Fraser Scobie; Gordon D. Love; Dirk Seidel; Velitchko Manahilov

PURPOSE Visibility of low-spatial frequency stimuli improves when their contrast is modulated at 5 to 10 Hz compared with stationary stimuli. Therefore, temporal modulations of visual objects could enhance the performance of low vision patients who primarily perceive images of low-spatial frequency content. We investigated the effect of retinal-image jitter on word recognition speed and facial emotion recognition in subjects with central visual impairment. METHODS Word recognition speed and accuracy of facial emotion discrimination were measured in volunteers with AMD under stationary and jittering conditions. Computer-driven and optoelectronic approaches were used to induce retinal-image jitter with duration of 100 or 166 ms and amplitude within the range of 0.5 to 2.6° visual angle. Word recognition speed was also measured for participants with simulated (Bangerter filters) visual impairment. RESULTS Text jittering markedly enhanced word recognition speed for people with severe visual loss (101 ± 25%), while for those with moderate visual impairment, this effect was weaker (19 ± 9%). The ability of low vision patients to discriminate the facial emotions of jittering images improved by a factor of 2. A prototype of optoelectronic jitter goggles produced similar improvement in facial emotion discrimination. Word recognition speed in participants with simulated visual impairment was enhanced for interjitter intervals over 100 ms and reduced for shorter intervals. CONCLUSIONS Results suggest that retinal-image jitter with optimal frequency and amplitude is an effective strategy for enhancing visual information processing in the absence of spatial detail. These findings will enable the development of novel tools to improve the quality of life of low vision patients.


Ophthalmic and Physiological Optics | 2011

Accommodation steps, target spatial frequency and refractive error

Niall C. Strang; Mhairi Day; Lyle S. Gray; Dirk Seidel

Citation information: Strang NC, Day M, Gray LS & Seidel D. Accommodation steps, target spatial frequency and refractive error. Ophthalmic Physiol Opt 2011, 31, 444–455. doi: 10.1111/j.1475‐1313.2011.00855.x


Optometry and Vision Science | 2015

Is Pupil Diameter Influenced by Refractive Error

Janis B. Orr; Dirk Seidel; Mhairi Day; Lyle S. Gray

PurposeTo investigate the relationship between pupil diameter and refractive error and how refractive correction, target luminance, and accommodation modulate this relationship. MethodsSixty emmetropic, myopic, and hyperopic subjects (age range, 18 to 35 years) viewed an illuminated target (luminance: 10, 100, 200, 400, 1000, 2000, and 4100 cd/m2) within a Badal optical system, at 0 diopters (D) and −3 D vergence, with and without refractive correction. Refractive error was corrected using daily disposable contact lenses. Pupil diameter and accommodation were recorded continuously using a commercially available photorefractor. ResultsNo significant difference in pupil diameter was found between the refractive groups at 0 D or −3 D target vergence, in the corrected or uncorrected conditions. As expected, pupil diameter decreased with increasing luminance. Target vergence had no significant influence on pupil diameter. In the corrected condition, at 0 D target vergence, the accommodation response was similar in all refractive groups. At −3 D target vergence, the emmetropic and myopic groups accommodated significantly more than the hyperopic group at all luminance levels. There was no correlation between accommodation response and pupil diameter or refractive error in any refractive group. In the uncorrected condition, the accommodation response was significantly greater in the hyperopic group than in the myopic group at all luminance levels, particularly for near viewing. In the hyperopic group, the accommodation response was significantly correlated with refractive error but not pupil diameter. In the myopic group, accommodation response level was not correlated with refractive error or pupil diameter. ConclusionsRefractive error has no influence on pupil diameter, irrespective of refractive correction or accommodative demand. This suggests that the pupil is controlled by the pupillary light reflex and is not driven by retinal blur.


Vision Research | 2014

Quantifying interactions between accommodation and vergence in a binocularly normal population.

Laura E. Sweeney; Dirk Seidel; Mhairi Day; Lyle S. Gray

Stimulation of the accommodation system results in a response in the vergence system via accommodative vergence cross-link interactions, and stimulation of the vergence system results in an accommodation response via vergence accommodation cross-link interactions. Cross-link interactions are necessary in order to ensure simultaneous responses in the accommodation and vergence systems. The crosslink interactions are represented most comprehensively by the response AC/A (accommodative vergence) and CA/C (vergence accommodation) ratios, although the stimulus AC/A ratio is measured clinically, and the stimulus CA/C ratio is seldom measured in clinical practice. The present study aims to quantify both stimulus and response AC/A and CA/C ratios in a binocularly normal population, and determine the relationship between them. 25 Subjects (mean ± SD age 21.0 ± 1.9 years) were recruited from the university population. A significant linear relationship was found between the stimulus and response ratios, for both AC/A (r² = 0.96, p < 0.001) and CA/C ratios (r² = 0.40, p < 0.05). Good agreement was found between the stimulus and response AC/A ratios (95% CI -0.06 to 0.24 MA/D). Stimulus and response CA/C ratios are linearly related. Stimulus CA/C ratios were higher than response ratios at low values, and lower than response ratios at high values (95% CI -0.46 to 0.42 D/MA). Agreement between stimulus and response CA/C ratios is poorer than that found for AC/A ratios due to increased variability in vergence responses when viewing the Gaussian blurred target. This study has shown that more work is needed to refine the methodology of CA/C ratio measurement.


Ophthalmic and Physiological Optics | 2007

Technical Note: Effect of contact lenses on measurement of the accommodation microfluctuations

Mhairi Day; Niall C. Strang; Dirk Seidel; Lyle S. Gray

Aim:  Dynamic measurement of accommodation in subjects with myopia usually involves recording through soft contact lenses (CLs) to correct the refractive error. Conversely, dynamic accommodation measurement in emmetropic control subjects is generally undertaken without any corrective lenses. The aim of this experiment was to determine whether CL correction affects the measurement of accommodation microfluctuations using infrared refractometry, and whether this needs to be considered in studies which attempt to compare accommodation responses between the two groups.


Ophthalmic and Physiological Optics | 2010

The effect of proximity on open-loop accommodation responses measured with pinholes.

K.A. Morrison; Dirk Seidel; Niall C. Strang; Lyle S. Gray

Open‐loop accommodation levels were measured in 41 healthy, young subjects using a Shin‐Nippon SRW‐5000 autorefractor in the three viewing conditions: a small physical pinhole pupil (SP), an optically projected pinhole in Maxwellian view (MV) and in the dark (DF). The target viewed through the pinholes was a high‐contrast letter presented at 0 D vergence in a +5 D Badal lens system. Overall, results showed that SP open‐loop accommodation levels were significantly higher than MV and DF levels. Subjects could be divided into two distinct subgroups according to their response behaviour: responders to the proximal effect of the small physical pinhole (SP accommodation > MV accommodation) and non‐responders to the proximal effect of the small physical pinhole (SP accommodation ≈ MV accommodation). Correlation analysis demonstrated that open‐loop accommodation for both pinhole conditions was correlated with DF for the responders, while for the non‐responders SP and MV accommodation were correlated, but were not related to DF accommodation. This suggests that under open‐loop conditions some individuals’ accommodation levels are mainly affected by proximal and cognitive factors (responders) while others are guided primarily by the presence of the more distal target (non‐responders). In conclusion, MV reduces the proximal effect of the physical pinhole and produces open‐loop accommodation responses which are more consistent than SP and DF responses.

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Dive into the Dirk Seidel's collaboration.

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Lyle S. Gray

Glasgow Caledonian University

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Niall C. Strang

Glasgow Caledonian University

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Mhairi Day

Glasgow Caledonian University

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Velitchko Manahilov

Glasgow Caledonian University

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Gordon Heron

Glasgow Caledonian University

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Sven Mucke

Glasgow Caledonian University

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Laura E. Sweeney

Glasgow Caledonian University

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Lucy Macfadden

Glasgow Caledonian University

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Ana Fernandez

Glasgow Caledonian University

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