Dmitrii L. Chizhov

Synthesis of polyfluoroalkyl-containing 1,3,5-triketones

Abstract Synthesis of polyfluoro 1,3,5-triketones by modification of Claisen condensation is described.

Chelates of Fluoroalkyl Containing Enaminoketones

The structure and areas of practical application of fluoroalkyl containing enaminoketone chelates with d-metals are reviewed. Synthesis of ligands and the routes to the regioisomeric enaminoketones are also considered.

Reactions of fluoroalkyl-containing bis-β-diketones with hydrazine and hydroxylamine

Polyfluoroalkyl-containing bispyrazoles, bis(5-hydroxy-Δ2-isoxazolines), and bisisoxazoles were synthesized for the first time by reactions of polyfluoroalkyl-containing bis-β-diketones with hydrazine, phenylhydrazine, and hydroxylamine, respectively.

Effective fluoroalkylation of aldehydes by σ-perfluoroalkyl-iron compounds

Abstract Organoiron compounds with σ-perfluoroalkyl-iron bonds are well-known and common compounds convenient to prepare and handle. However, their application in organic synthesis was restricted to the introduction of fluoroalkyl group only into electron rich organic molecules such as arenes and thiols [I.I. Gerus, Yu.L. Yagupolskii and L.M. Yagupolskii, J. Org. Chem. (Russ. ed.), 21 (1985) 1852; C.G. Krespan, J. Fluor. Chem., 40 (1988) 129]. In this work we have succeeded in the use of the perfluoroalkyltetracarbonyliron iodides for the nucleophilic fluoroalkylation of aldehydes: The reaction is rapid (∼ 1 h), easy to carry out and does not require an inert atmosphere. From the synthetic point of view it is promising since the starting organoiron compounds are readily prepared from fluoroalkyl iodides and solid substances stable in air.