Eckhard Schwenner
Bayer
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Publication
Featured researches published by Eckhard Schwenner.
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes | 1991
Sharon Stone-Elander; Per E. Roland; Eckhard Schwenner; Christer Halldin; Lennart Widén
Nimodipine, an antagonist of the L-type calcium ion channel, was labelled with 11C for in vivo positron emission tomography studies of dihydropyridine binding in the human brain. The synthesis was based on esterification of the corresponding acid (W2100) using [2-11C]isopropyl iodide as the labelling precursor. The effects of different bases, solvent mixtures and reaction temperatures on radiochemical yields were investigated. The synthesis including purification by semi-preparative reversed-phase HPLC, required 60-65 min. Conversion of [2-11C]isopropyl iodide to [isopropyl-11C] nimodipine was of the order of 60-80%. The radiochemical yield (isolated) was 20-25%, based on [11C]carbon dioxide. The specific activity of the isolated product varied from 4-40 GBq/mumol (end-of-synthesis).
Archive | 1994
Antonius L obberding; Burkhard Mielke; Christoph Schwemler; Eckhard Schwenner; Udo Stropp; Wolfgang Springer; Axel Kretschmer; Thorsten P otter
Archive | 1993
Eckhard Schwenner; Gaetan Ladouceur; Hans-Joachim Kabbe; Thomas M. Aune
Archive | 1993
Eckhard Schwenner; Gaetan Ladouceur; Hans-Joachim Kabbe; Thomas M. Aune
Archive | 1985
David Triggle; Eckhard Schwenner; Günther Dr. Kinast; Stanislav Kazda; Andreas Dr. Knorr; Bernward Garthoff
Archive | 1994
Axel Kretschmer; Antonius Dr. Löbberding; Burkhard Mielke; Thorsten Pötter; Christoph Schwemler; Eckhard Schwenner; Wolfgang Springer; Udo Stropp
Archive | 1994
Antonius Dr. Löbberding; Burkhard Mielke; Christoph Schwemler; Eckhard Schwenner; Udo Stropp; Wolfgang Springer; Axel Kretschmer; Thorsten Pötter
Archive | 1994
Eckhard Schwenner; Gaéton Ladouceur; Thomas M. Aune
Archive | 1987
Eckhard Schwenner; Günther Dr. Kinast; Andreas Dr. Knorr; Stanislav Kazda
Archive | 1988
Jürgen Dipl.-Ing. Stoltefuss; Eckhard Schwenner; Martin Bechem; Claudia Hirth; Michael Kayser; Matthias Schramm; Johannes-Peter Stasch