Edward B. Savage
Cleveland Clinic
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Featured researches published by Edward B. Savage.
The Annals of Thoracic Surgery | 2014
Edward B. Savage; Paramita Saha-Chaudhuri; Craig R. Asher; J. Matthew Brennan; James S. Gammie
BACKGROUND National prosthesis use in active aortic valve infective endocarditis (IE) is unreported. Prosthesis usage and outcomes in patients undergoing an aortic valve operation with active IE was evaluated. METHODS The Society of Thoracic Surgeons Adult Cardiac Surgery Database was used to identify patients with active IE who underwent an aortic valve operation from January 1, 2005, to June 30, 2011. All patients with active IE were included. Demographics, procedures, outcomes, and trends were analyzed. RESULTS Of 11,560 patients who were identified as having active IE, 8,421 (73%) had no prior operations (primary) and 3,139 (27%) had a history of any prior cardiac operation (reoperative). Operations for primary vs reoperative patients included isolated replacement in 88.5% vs 58.7% and root replacement in 7.2% vs 29.9%. Major morbidity was 60.8% vs 68%, and the unadjusted mortality rate was 9.8% vs 21.1%. Over time, for primary operations, biologic valve use increased (57% to 67%), and mechanical and homograft valve use decreased (30% to 24% and 9% to 6%; p < 0.001). For reoperations, biologic valve use increased (38% to 52%), and mechanical and homograft use decreased (20% to 17% and 38% to 28%; p < 0.001). Homografts were used more often in reoperations (32% vs 7%). CONCLUSIONS Morbidity and mortality rates death are high for operations for active IE. Biologic valves were increasingly used vs mechanical and homograft valves. Homograft valves were used more often in reoperative patients after any prior cardiac operation. The mortality rate varied among prosthesis groups but may be related to the severity of infection and type of procedure performed.
Cureus | 2018
Saketh Palasamudram Shekar; Pablo Bajarano; Anas Hadeh; Edward Rojas; Samantha R Gillenwater; Edward B. Savage; Jinesh P. Mehta
Bronchiectasis is a well-known entity where the airways abnormally dilate losing their natural function. Most common causes of non-cytic fibrosis bronchiectasis in the middle age group include secondary immunodeficiency, aspiration, and allergic bronchopulmonary aspergillosis (ABPA). Obstructive foreign body is an uncommon cause of bronchiectasis and is often a missed diagnosis in a localized disease. Foreign bodies can be missed making the diagnosis and treatment more challenging and hence foreign body bronchiectasis should be considered in patients presenting with focal disease. Here we describe a patient with a retained foreign body that was discovered post lobectomy during gross pathological examination of the specimen with no significant aspiration history, non-diagnostic imaging of the chest and negative bronchoscopy.
The Annals of Thoracic Surgery | 2017
Sandor Toledo; Elizabeth Grigoryan; Jacobo Kirsch; Edward B. Savage
A 20-year-old woman presented with palpitations. Echocardiography demonstrated a left ventricular mass involving the posterolateral apical wall and protruding into the ventricular cavity. Evaluation with magnetic resonance imaging (MRI) suggested fatty consistency with all edges well defined except the medial, which was ill defined, raising concern for an invasive liposarcoma. Open core needle biopsy demonstrated mature adipocytes infiltrating the myocardium with extensive interstitial fibrosis. The diagnosis was left-dominant arrhythmogenic cardiomyopathy. Two-year MRI follow-up demonstrates no change in size. This case illustrates the use and limits of cardiac MRI and the value of open cardiac biopsy in diagnosis.
Case Reports | 2012
Jonathan Ryan Schroeder; Anjan Kumar; Edward B. Savage; Franck Rahaghi
A 31-year-old postal worker was diagnosed with bilateral thoracic outlet syndrome and scheduled for the first of two surgeries. The first procedure involved removal of the right first cervical rib, anterior and middle scalenes. On postoperative day 4, he developed shortness of breath. Chest radiograph showed a new pleural effusion on the right. Thoracentesis revealed a yellowish-red thick effusion. Based on the initial look of the fluid it was thought to be a haemorrhagic effusion with a purulent component, further testing revealed that he had developed a chylothorax. The patient was placed on a medium-chain triglyceride diet followed by chest tube drainage. After one day, the chest tube was removed due to minimal drainage, and he was discharged home the next day. Keeping this patient without food, on total parental nutrition, or pursuing surgical intervention was not necessary, as he had an excellent outcome from a very rare surgical complication.
Texas Heart Institute Journal | 2011
Vishal Mundra; Edward B. Savage; Gian M. Novaro; Craig R. Asher
The Journal of Thoracic and Cardiovascular Surgery | 2017
Edward B. Savage
Journal of Ayub Medical College Abbottabad | 2017
Syed Shahmeer Raza; Farhan Ullah; Chandni; Edward B. Savage
Chest | 2016
James Benjamin Gleason; Basheer Tashtoush; Jinesh Mehta; Edward B. Savage; Felipe Martinez; Atul C. Mehta
Journal of The American College of Surgeons | 2015
Yaniv Cozacov; Nagi Muneer; Edward B. Savage; William Kernan; Margaret E. Gilot; Cassann N. Blake
Chest | 2014
Faria Nasim; Jacobo Kirsch; Edward B. Savage