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Dive into the research topics where Elif Ergul Ekiz is active.

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Featured researches published by Elif Ergul Ekiz.


Meat Science | 2012

Effect of pre-slaughter management regarding transportation and time in lairage on certain stress parameters, carcass and meat quality characteristics in Kivircik lambs.

Bülent Ekiz; Elif Ergul Ekiz; Ömür Koçak; Hulya Yalcintan; Alper Yilmaz

Thirty Kivircik lambs were used to investigate effect of pre-slaughter treatment on certain haematological and biochemical parameters, carcass and meat quality characteristics. Lambs were divided into three treatments: 75 min transport and lairage for 18 h (TS-L18 h); 75 min transport and lairage for 30 min (TS-L30 min) and no pre-slaughter transport and lairage for 30 min (NTS). Treatment, as a main effect, did not influence haematological and biochemical parameters, but sampling time significantly affected these parameters, except total protein. Plasma cortisol concentration at exsanguination in TS-18 h, TS-30 min and NTS treatments were 117.34, 119.23 and 72.51 ng/ml, respectively. pH of longissimus dorsi muscle was higher in TS-L30 min than other treatments. TS-L30 min lambs had the highest shear force value, the lowest WHC and cooking loss. TS-L30 min treatment yielded the darkest meat immediately after cutting and 1 h later. Meat redness, yellowness and chroma values were similar in treatments.


Meat Science | 2012

Effects of suckling length (45, 75 and 120 d) and rearing type on cortisol level, carcass and meat quality characteristics in Kivircik lambs

Bülent Ekiz; Elif Ergul Ekiz; Hulya Yalcintan; Ömür Koçak; Alper Yilmaz

Forty lambs were used to investigate effects of suckling length and rearing type (single and twin) on welfare parameters, carcass and meat quality characteristics. SC-45 and SC-75 lambs were weaned at 45-d and 75-d of age, respectively, whereas SC-120 lambs were not weaned until slaughter age of 120-d. The elevated cortisol concentration due to weaning stress returned to pre-weaning level at 2-d after weaning. SC-120 lambs had higher daily gain, plasma cortisol and glucose levels at exsanguination, hot carcass weight, dressing percentage and fatness score than weaned lambs. Suckling length did not influence instrumental meat quality characteristics, except shear force. SC-45 lambs had tougher meat than other groups according to instrumental and sensory analyses. SC-75 and SC-120 lambs had similar meat shear force value and sensory scores. Single lambs had higher daily gain, and greater scores for carcass characteristics and sensory evaluation, and lower pH(24) and shear force than twin lambs.


Veterinary Clinical Pathology | 2011

Frequency of dog erythrocyte antigen 1.1 in 4 breeds native to different areas in Turkey

Elif Ergul Ekiz; Murat Arslan; Mukaddes Özcan; Guldal Inal Gultekin; Ozlem Yildiz Gulay; Turgut Kirmizibayrak; Urs Giger

BACKGROUND Dog erythrocyte antigen (DEA) 1.1 is the most important RBC antigen clinically, as it is highly immunogenic and causes acute hemolytic transfusion reactions (HTR) in sensitized dogs. OBJECTIVES The aims of this study were to determine the frequency of DEA 1.1 expression in 4 Turkish dog breeds, and to estimate the potential risk of HTR when blood from a DEA 1.1-positive donor is administered to a DEA 1.1-negative recipient following sensitization by a prior mismatched transfusion. METHODS EDTA blood samples (n = 178) were typed for DEA 1.1 using a commercial gel-column agglutination test (ID-Gel-Test Canine DEA 1.1). Probabilities of sensitization and risk of an HTR were calculated. RESULTS The frequency of positivity for DEA 1.1 among Kars (n = 59), Kangal (n = 53), Akbash (n = 50), and Catalburun (n = 16) breeds was 71.2%, 67.9%, 60.0%, and 50.0%, respectively. Potential risk for occurrence of an HTR after administration of blood from a dog of the same breed ranged from 12.5% to 14.8%, whereas HTR induced by blood of a dog from a different breed ranged from 7.2% to 25.3%. CONCLUSIONS The frequency of DEA 1.1-positive dogs among 4 Turkish breeds is high compared with that of most other breeds previously surveyed. The predicted risk of both sensitization and occurrence of DEA 1.1-related HTR following transfusion between dogs of either the same or different Turkish breeds was considerable. Although few dogs are transfused ≥4 days after the first transfusion, we recommend that (1) all donors and recipients be typed for DEA 1.1, (2) DEA 1.1-negative recipients receive only DEA 1.1-negative blood, and (3) blood be cross-matched prior to transfusing any dog ≥4 days after the first transfusion. These guidelines are also applicable to other breeds and countries.


Poultry Science | 2015

The effect of furnished cages on the immune response of laying hens under social stress

Erdal Matur; Evren Eraslan; Ibrahim Akyazi; Elif Ergul Ekiz; Hüseyin Eseceli; Mehmet Keten; Kemal Metiner; Deniz Aktaran Bala

The aim of the study was to examine the effects of cage furnishing and social stress on some lymphoid organ weight and innate, cell-mediated, and humoral immune responses in laying hens. Sixty-four chickens were used. The chickens were divided into 2 groups; one of the groups was reared in furnished cages (RFC) and the other was reared in conventional cages (RCC). In wk 17, social stress was applied. Heterophil and lymphocyte percentages; liver, spleen, thymus, and bursa of Fabricius weights; phagocytic activity; oxidative burst and chemotaxic activity of heterophil; CD4+ and CD8+ cell proportions; and antibody production were measured. The effect of rearing methods was significant on heterophil, lymphocyte percentage, heterophil/lymphocyte (H/L) ratio, and antibody production. Heterophil percentage and H/L ratio were lower (P=0.001, P=0.001, respectively), and antibody production was higher (P=0.003) in RFC hens compared to RCC hens. The main effect of social stress was also significant on heterophil, lymphocyte percentages, and H/L ratio. Heterophil percentage was higher (P=0.049); H/L ratio tended to be higher (P=0.068); and lymphocyte percentage tended to be lower (P=0.072) due to stress. In addition, thymus and bursa of Fabricius weights tended to be lower (P=0.073 and P=0.074, respectively) in stressed hens. There were significant interactions between rearing methods and social stress on oxidative burst, chemotaxic activity, and CD4+ and CD8+ proportion (P=0.001, P=0.004, P=0.054, and P=0.001, respectively). These parameters were significantly higher in RFC hens, when they were exposed to stress. On the other hand, they did not differ in RCC or unstressed RFC hens. These results indicated that cage furnishing positively affected heterophil functions, CD4+ and CD8+ cell proportions, and antibody production. Therefore, we suggest that cage furnishing, which is recommended for improving the welfare of animals, is also beneficial for improving the immune response of hens under the stress condition.


World Journal of Gastroenterology | 2013

Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats.

Ibrahim Akyazi; Evren Eraslan; Ahmet Gülçubuk; Elif Ergul Ekiz; Zeynep L Çırakli; Damla Haktanir; Deniz Aktaran Bala; Mete Özkurt; Erdal Matur; Mukaddes Özcan

AIM To investigate the effects of long term pretreatment with low-, medium- and high-dose aspirin (acetylsalicylic acid, ASA) on a model of acute pancreatitis (AP) induced in rats. METHODS Forty male Wistar rats were used. Three experimental groups, each consisting of eight animals, received low- (5 mg/kg per day), medium- (150 mg/kg per day) and high-dose (350 mg/kg per day) ASA in supplemented pellet chow for 100 d. Eight animals, serving as the AP-control group, and another eight, serving as reference value (RV) group, were fed with standard pellet chow for the same period. After pretreatment, AP was induced in the experimental animals by intraperitoneal administration of cerulein (2 × 50 μg/kg), while the RV group received saline in the same way. Twelve hours after the second injection, the animals were sacrificed. Pancreatic tissue and plasma samples were collected. One part of the collected pancreatic tissues was used for histopathological evaluation, and the remaining portion was homogenized. Cytokine levels [tumor necrosis factor, interleukin (IL)-1β, IL-6], hemogram parameters, biochemical parameters (amylase and lipase), nuclear factor-κB, aspirin triggered lipoxins and parameters related to the antioxidant system (malondialdehyde, nitric oxide, hemeoxygenase-1, catalase and superoxide dismutase) were measured. RESULTS Cerulein administration induced mild pancreatitis, characterized by interstitial edema (total histopathological score of 5.88 ± 0.44 vs 0.25 ± 0.16, P < 0.001). Subsequent pancreatic tissue damage resulted in an increase in amylase (2829.71 ± 772.48 vs 984.57 ± 49.22 U/L, P = 0.001) and lipase (110.14 ± 75.84 U/L vs 4.71 ± 0.78 U/L, P < 0.001) in plasma, and leucocytes (6.89 ± 0.48 vs 4.36 ± 0.23, P = 0.001) in peripheral blood. Cytokines, IL-1β (18.81 ± 2.55 pg/μg vs 6.65 ± 0.24 pg/μg, P = 0.002) and IL-6 (14.62 ± 1.98 pg/μg vs 9.09 ± 1.36 pg/μg, P = 0.04) in pancreatic tissue also increased. Aspirin pretreatment reduced the increase in the aforementioned parameters to a certain degree and partially improved the histopathological alterations caused by cerulein. No evidence of side effects related to chronic ASA administration (e.g., inflammation or bleeding) was observed in the gastrointestinal tract in macroscopic and histopathological examination. CONCLUSION Long term ASA pretreatment could prevent and/or ameliorate certain hematological, serological and histological alterations caused by cerulein-induced AP.


Animal Science Journal | 2016

The effects of environmental enrichment and transport stress on the weights of lymphoid organs, cell-mediated immune response, heterophil functions and antibody production in laying hens

Erdal Matur; Ibrahim Akyazi; Evren Eraslan; Elif Ergul Ekiz; Hüseyin Eseceli; Mehmet Keten; Kemal Metiner; Deniz Aktaran Bala

The effects of environmental enrichment and transport stress on the immune system were investigated in laying hens. A total of 48 1-day-old chickens were used, half of the chickens were reared in conventional cages (RCC) and the rest in enriched cages (REC). Transport stress was applied in the 17th week. Liver weight decreased, spleen and bursa of Fabricius weights, white blood cell count, CD4+ and CD8+ cell proportions increased due to the transport. Environmental enrichment significantly increased antibody production and tended to increase monocyte percentage and CD8+ cell proportion. The effect of transport on, heterophil (H) and lymphocyte (L) percentages was not significant in RCC chickens. While heterophil percentage and H:L ratio increased, lymphocyte percentage decreased in REC chickens subjected to transport. Transport stress increased heterophil functions both in REC and RCC chickens, but the increase was higher in REC hens than in RCC hens. In conclusion, although environmental enrichment did not neutralize the effect of transport on lymphoid organs, it activated the non-specific immune system, cellular and the humoral branches of the specific immune system by increasing heterophil functions, CD8+ cells and antibody production, respectively. Therefore, environmental enrichment suggested for improving animal welfare may also be beneficial to improve the immune system of birds exposed to stress.


Turkish Journal of Veterinary & Animal Sciences | 2018

Certain behavioral characteristics and stress responses of out-of-breeding ewes and rams during an intensive fattening program

Hulya Yalcintan; Elif Ergul Ekiz; Bülent Ekiz; Ömür Koçak; Deniz Aktaran Bala; Alper Yilmaz

The aim was to investigate behaviors and stress responses of rams and ewes in an intensive fattening period. Out-of-breeding rams (Hemsin = 10, Karakul = 10) and ewes (Hemsin = 8, Karakul = 10) were used in the study. Sheep and rams belonging to each breed were placed into four different pens. Behavioral observations (individual, feeding, abnormal self-grooming behaviors) were performed 2 days a week for two groups a day for 1 h. Blood samples were collected at the beginning, at the 4th week, and at the end of the fattening period. Karakul ewes displayed significantly more feeding and rumination behavior than Hemsin ewes, while there was no significant difference between ram groups. Ewes displayed more lying and rumination behavior than rams in the current study. On the other hand, rams were more active than ewes and also showed more abnormal behavior (butting other animals) during the fattening period. Sheep breed had no influence on packed cell volume (PCV), hemoglobin (Hb) concentration, or cortisol level at any sampling time. PCV, Hb, and cortisol levels at the middle of the fattening period were higher in ewes than rams. In conclusion, the behavioral repertoire of Hemsin and Karakul breeds in intensive fattening does not reveal any stress responses.


Phytotherapy Research | 2007

Tumour preventive effect of Aloe vera leaf pulp lectin (Aloctin I) on Ehrlich ascites tumours in mice

Nuriye Akev; Gulhan Turkay; Ayse Can; Aydın Gürel; Funda Yildiz; Hasret Yardibi; Elif Ergul Ekiz; Hafize Uzun


European Journal of Cancer Prevention | 2007

Effect of Aloe vera leaf pulp extract on Ehrlich ascites tumours in mice.

Nuriye Akev; Gulhan Turkay; Ayse Can; Aydın Gürel; Funda Yildiz; Hasret Yardibi; Elif Ergul Ekiz; Hafize Uzun


İstanbul Üniversitesi Veteriner Fakültesi Dergisi | 2012

The Effects of Transport Stress on Certain Welfare Parameters and Behaviours in Red Karaman,Imroz, Sakız and Karakul Rams

Bülent Ekiz; Elif Ergul Ekiz; Hulya Yalcintan; Ömür Koçak; Alper Yilmaz; Halil Güneş

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