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Featured researches published by Elif Nisa Unlu.


Diagnostic and interventional imaging | 2017

Assessment of anterior subcutaneous hypersignal on proton-density-weighted MR imaging of the knee and relationship with anterior knee pain.

Elif Nisa Unlu; Y. Turhan; D.M. Kos; A.A. Safak

PURPOSE The purpose of this study was to evaluate the prevalence of anterior subcutaneous hypersignal indicating edema on proton-density (PD)-weighted MRI of the knee and to determine whether reporting anterior edema is clinically relevant. MATERIALS AND METHODS One hundred and ninety-one knee MRIs from 162 patients were reviewed for anterior subcutaneous edema. There were 92 men and 70 women with a mean age of 41.72years±13.92 (SD) (range, 15-80years) years and a mean body weight of 75.94kg±12.54 (SD) (range, 50-130kg). The MRI findings were compared with patient age, gender, body weight, history of repetitive microtrauma and clinical findings. Patellar and trochlear chondropathy, medial plica, joint effusion, synovitis, infrapatellar fat-pad signal intensity, suprapatellar fat-pad signal intensity with mass effect, quadriceps and patellar tendon abnormalities were also reviewed. RESULTS An anterior hypersignal on PD-weighted MRI was detected in 158/191 MR examinations (82.7%) and 104 (84.6%) of these cases had histories of anterior knee pain. No correlation between anterior pain and anterior edema was found (P=0.42). Age (P<0.0001), weight (P<0.0001), and repetitive microtrauma (P=0.001) were identified as significant variables associated with anterior edema. CONCLUSION Anterior edema may be a physiological phenomenon or degenerative change related to patient age, weight, and knee movement or mechanics. It should not be reported as a pathological finding on MRI unless clinical findings support regional infection or inflammation.


Journal of Computer Assisted Tomography | 2016

Is There a Relationship Between Paratracheal Air Cysts and Upper Lobe Fibrosis

Elif Nisa Unlu; Ege Gulec Balbay; Mertay Boran; Mehmet Ali Sungur; Ayla Buyukkaya; Alp Alper Safak

Objective The purpose of this study was to determine the characteristics of paratracheal air cysts (PACs) and their relationship with upper lobe pulmonary fibrosis. Materials and Methods The routine thoracic computed tomography scans of 3549 patients carried out between January 2014 and April 2015 were retrospectively evaluated. The presence, location, structural characteristics (uniloculated or multiloculated), number of cysts, and anterior-posterior and transverse dimensions of the PAC and its communication with the tracheal lumen were evaluated. The presence of upper lobe fibrosis, emphysema, and bronchiectasis was also evaluated. The relationship between upper lobe fibrosis, emphysema, bronchiectasis, and the presence of paratracheal cysts was evaluated in all patients. An equal number of randomized patients with no paratracheal cysts were selected as a control group. Results A total of 190 PAC cases were diagnosed, with a prevalence rate of 5.35%: 146 (76.8%) of the cases were men, 44 (23.2%) were female, and the mean (SD) age was 53.79 (16.64) years (range, 12–89 years). The control group included 105 men (57.4%) and 78 women (42.6%), and the mean (SD) age was 53.87 (16.65) years (range, 13–87 years). The groups were similar in terms of age (P = 0.876), whereas the proportion of men in the PAC group was significantly higher (P < 0.001). Most of the PACs were located on the right side (n = 188, 98.9%). The incidence of fibrosis in the paratracheal cyst group was 45.8% (n = 87) compared with 19.5% (n = 37) in the control group; this difference was statistically significant (P < 0.001). The prevalence rates of emphysema in the cyst group and the control group were 29.5% (n = 56) and 11.6% (n = 22), respectively, and the difference was statistically significant (P < 0.001). When the groups were compared regarding bronchiectasis (scar and non–scar related), the rate of bronchiectasis in the paratracheal cyst group was 17.9% (n = 34), compared with 3.7% (n = 7) in the control group; this difference was statistically significant (P < 0.001). Conclusions Paratracheal air cysts are relatively common, but the etiology is still unclear. We detected increased rates of cyst formation that may result from the traction effect on the tracheal wall in the presence of upper lobe fibrosis.


Turkish journal of haematology : official journal of Turkish Society of Haematology | 2016

T-Cell Lymphoma Presenting with Auricular and Parotid Gland Involvement.

Birgül Öneç; Alper Koç; Elif Nisa Unlu; İlhan Ünlü; Huseyin Yaman; Durdu Mehmet Köş

Conflict of Interest: The authors of this paper have no conflicts of interest, including specific financial interests, relationships, and/or affiliations relevant to the subject matter or materials included. References 1. Roschewski M, Wilson WH. EBV-associated lymphomas in adults. Best Pract Res Clin Haematol 2012;25:75-89. 2. Niedobitek G. Epstein-Barr virus infection in the pathogenesis of nasopharyngeal carcinoma. Mol Pathol 2000;53:248-254. 3. Al-Hakeem DA, Fedele S, Carlos R, Porter S. Extranodal NK/T-cell lymphoma, nasal type. Oral Oncol 2007;43:4-14. 4. Jaccard A, Hermine O. Extranodal natural killer/T-cell lymphoma: advances in the management. Curr Opin Oncol 2011;23:429-435. 5. Liu QF, Wang WH, Wang SL, Liu YP, Huang WT, Lu N, Zhou LQ, Ouyang H, Jin J, Li YX. Immunophenotypic and clinical differences between the nasal and extranasal subtypes of upper aerodigestive tract natural killer/T-cell lymphoma. Int J Radiat Oncol Biol Phys 2014;88:806-813. 6. Liang R. Diagnosis and management of primary nasal lymphoma of T-cell or NK-cell origin. Clin Lymphoma 2000;1:33-38. 7. Hasserjian RP, Harris NL. NK-cell lymphomas and leukemias: a spectrum of tumors with variable manifestations and immunophenotype. Am J Clin Pathol 2007;127:860-868. 8. Kwong YL. Natural killer-cell malignancies: diagnosis and treatment. Leukemia 2005;19:2186-2194.


American Journal of Emergency Medicine | 2016

An unusual cause of recurrent spontaneous pneumothorax: the Mounier-Kuhn syndrome

Elif Nisa Unlu; Ali Nihat Annakkaya; Ege Gulec Balbay; Leyla Yilmaz Aydin; Sinem Safçı; Mertay Boran; Derya Guclu

We present a case of 63-year-old man who was referred to the emergency department with a right-sided pneumothorax. He had a history of spontaneous pneumothorax for 2 times. The chest computed tomographic scan showed tracheobronchomegaly with an increase in the diameter of the trachea and right and left main bronchus. Fiberoptic bronchoscopy revealed enlarged trachea and both main bronchus with diverticulas. These findings are consistent with a diagnosis of Mounier-Kuhn syndrome. Mounier-Kuhn syndrome is a rare clinical and radiologic condition. It is characterized by a tracheal and bronchial dilation. Diagnosis is made by computed tomography and bronchoscopy. Mounier-Kuhn syndrome should be kept in mind in the differential diagnosis of recurrent spontaneous pneumothorax.


Eurasian Journal of Pulmonology | 2015

A 37-Year-Old Asymptomatic Male Case of Mass Lesion in the Right Upper Zone detected on Chest x-Ray: What is your Diagnosis?

Fatih Alasan; Elif Nisa Unlu; Ali Nihat Annakkaya

A 34-year-old male patient was admitted to our polyclinic after detecting anomalous findings on chest radiography that was taken at his workplace as a control. The patient who was asymptomatic had no known chronic diseases. He worked in various factories that produce polyester from fiberglass. An anamnesis of 15 packs of cigarettes per year was present, and he was still an active smoker. In his physical examination, inspection was natural and secretory rough rales were heard in the right infrascapular region. His pulmonary function tests were within normal ranges. No pathological findings were detected in his routine blood tests. In his background, he reported that he survived a horse-drawn vehicle accident at age 5, in which the wheel of the vehicle went over his abdominal region and he therefore underwent a liver operation. No history of tuberculosis or of contact with tuberculosis was present. The tuberculin skin test was measured as 14 millimeters. On his chest radiography, in the right lung upper zone, in the subclavicular area, a parahilar mass with a diameter of 3–4 cm with smooth margins and lobulation was observed (Figure 1). Because a hyperlucent area surrounding the mass stood out, an expiration film was performed. On the expiratory radiography, the area surrounding the mass with local hyperinflation was monitored more carefully (Figure 2).


Case Reports | 2015

A rare case describing catastrophic destruction of the whole skeleton caused by severe hyperparathyroidism

Burcu Akkas; Busra Bedriye Demirel; Elif Nisa Unlu; Gülin Uçmak

Osteitis fibrosa cystica is a skeletal disorder seen in advanced stages of persistent hyperparathyroidism. Although the measurement of serum Ca and intact-parathormone levels provides early diagnosis and decreases the incidence of radiographic bone involvement, progressive major bone lesions may still be seen in developing countries even in the modern era. We aimed to share, by writing up this report, our astonishment after observing how the skeletal system can be ruined by persistent hyperparathyroidism.


American Journal of Otolaryngology | 2015

Evaluation of middle ear pressure in the early period after adenoidectomy in children with adenoid hypertrophy without otitis media with effusion

İlhan Ünlü; Elif Nisa Unlu; Gulin Gokcen Kesici; Ender Guclu; Huseyin Yaman; Ethem Ilhan; Selim Ulucanlı; Dilek Karadeniz; Mehmet Memis

OBJECTIVE Our aim was to analyze the changes in middle ear pressure in the early period after adenoidectomy in children with adenoid hypertrophy without otitis media with effusion. METHODS This prospective, descriptive study was performed on 64 patients (with normal tympanic membranes and tympanograms) undergoing adenoidectomy or adenotonsillectomy. All patients were operated by single experienced team using curettage technique. First tympanometry was done on the day before surgery. Tympanometry was repeated on the first-, third-, and seventh-day after the operation. Patients are separated into two groups according to age as patients younger than 6 years (Group A) and patients older than 6 years (Group B). All data were separately evaluated for each ear using Jerger Classification. RESULTS Of the 64 patients included in the study, 35 were male and 29 were female, and the average age was 91.01 ± 37.4 (35-178) months. Pathological decreases in the middle ear pressures of at least one ear were determined in 48 (75%) patients on the first postoperative day and in 10 (15.6%) patients on the third postoperative day. Middle ear pressures returned to preoperative values by the seventh postoperative day except in two patients. There were statistically significant differences (p<0.0001) among preoperative and first, third, and seventh postoperative day mean middle ear pressure. There were no statistically significant differences between Groups A and B in terms of tympanometry values of both ears obtained preoperatively and on the first, third, and seventh postoperative day. CONCLUSION In our study, temporary eustachian dysfunction and aural fullness occur in the early period after adenoidectomy and/or adenotonsillectomy. This situation may be due to post-surgery clots and edema in nasopharynx. We consider that tubal orifice can be exposed to surgical trauma as adenoidectomy surgeries are done by curettage technique. There is a need for comparative studies using microdebrider or laser adenoidectomy accompanied by an endoscope.


Case Reports | 2018

Median nerve entrapment due to accessory palmaris longus muscle: MRI and sonography findings

Derya Guclu; Mehmet Arican; Elif Nisa Unlu


European Respiratory Journal | 2017

Pulmonary functions, respiratory complaints and radiographic findings in aluminium foundry workers

Cahit Bilgin; Peri Arbak; Elif Nisa Unlu; Ege Gulec Balbay; Oner Balbay; Ali Nihat Annakkaya; Mehmet Akdogan


Türkiye Klinikleri Journal of Case Reports | 2016

A Rare Localization of Subcutaneous Dermatofifibroma: Case Report

İlhan Ünlü; Selim Ulucanlı; Elif Nisa Unlu; Murat Oktay; Ethem Ilhan

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Ali Nihat Annakkaya

Abant Izzet Baysal University

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