Emerson Filipe de Carvalho Nogueira

Partial glossectomy for treating extensive oral squamous cell papilloma

Squamous cell papilloma is a benign proliferation of the stratified squamous epithelium, which results in a papillary or warty mass, which is presumably induced by the human papilloma virus (HPV). Currently, there are at least 24 types of HPV associated with head and neck lesions; the pathogenesis of squamous papilloma is related to HPV types 6 and 11. The virulence and infectivity of oral papilloma is extremely low, unlike other HPV-induced lesions. Clinically, oral papillomas usually present as an exophytic, isolated, pedunculated, painless growth of less than 1 cm, the surface of which shows fingerlike or warty projections resembling a cauliflower, exhibiting color ranging from pink to pale white, depending on the degree of

Analysis of the presence and location of mast cells in periapical cysts and periapical granulomas

Objective: The aim of the present study was to locate mast cells in chronic periapical lesions (granulomas and cysts) by using histochemical techniques and toluidine blue staining. Methods: A quantitative, descriptive, cross-sectional and retrospective research was performed. The sample was obtained from histopathological reports in the archives of the laboratory of surgical pathology of the University of Pernambuco between November 2014 and May 2015. Results: Sixteen cases of granuloma and 21 cases of periapical cysts were selected. The stained slides were analyzed by two examiners at different times, in a double-blind study. Mast cells were found in 13 (61.9%) of the periapical cyst cases, located in the capsule of the lesion. In the periapical granuloma cases, mast cells were found in eight cases (50%), located in the granulation tissue. Conclusion: Mast cells were detected in both cysts and periapical granuloma, located in the capsule and granulation tissue, respectively. Mast cells were more prevalent in periapical cysts than in periapical granuloma.