Engin Şengül

Burun kanaması, anemi ve üst solunum yolunda obstrüksiyon yapan nadir bir etken, Sülükler: Üç olgu sunumu

The leech is an endoparasite for man and may cause lethal complications. In this article, we report two cases of 4 and 6-year-old who presented epistaxis due to leech infestasyon in nasopharynx and other case of 65-year-old adult with alzheimer who presented obstruction of upper respiratory tracks and anemia due to leech infestation in larynx. Especially in rural areas, it should always be borne in mind that leech might cause high mortality and morbidity due to serious complications such as anemia and obstruction of upper respiratory tracts and should be considered in evaluating the differential diagnosis of upper airway obstruction. J Clin Exp Invest 2012; 3 (3): 401-403

Radiologic and surgical findings in chronic suppurative otitis media.

Abstract Our aim in this study was to evaluate the efficiency of preoperative temporal bone computed tomography (CT) in detecting pathologic conditions in patients with chronic suppurative otitis media (CSOM). The intraoperative findings and temporal bone CT results of 350 patients who were diagnosed with CSOM between September 1, 2010, and June 1, 2013, were compared. Comparison parameters were as follows: the presence of cholesteatoma, erosion of the outer ear bone canal, erosion of the middle ear chain, erosion of the dural plate, erosion of the lateral semicircular canal, erosion of the sigmoid sinus wall, and dehiscence of the facial canal. The contribution of CT was limited in showing the outer ear canal destruction, dural plate destruction, facial canal destruction, lateral semicircular canal destruction, and destruction of the sigmoid sinus wall. However, CT was more sensitive in detecting cholesteatoma and erosion of the ossicular chain. These results indicate that preoperative CT of patients with CSOM serves as an important guide for otolaryngologists, although there are limitations in the evaluation of the CT results.

Larenks kanserlerinde, servikal metastaz sıklığı ile tümöre ait faktörlerin ilişkisi ve bu olguların cerrahi tedavi sonuçları

Objectives: We aimed to assess the associations between localization, size, stage and histopathological differentiation of primary tumor in larynx and neck metastases and the impact of disease stage on survival. Materials and methods: We analyzed the medical records of 333 laryngeal cancer patients who underwent total or partial laryngectomy as primary treatment, combined with neck dissection and/or postoperative radiotheraphy if required, between 2000 and 2010 years at our clinic. Age and gender of patients, tumor localization, size, stage and histopathological differentiation of tumor; presence of preoperative positive lymph nodes, performed operations, operation findings and histopathological results were analysed retrospectively. Results: Tumor localizations were glottic in 172 (51.6%) cases, supraglottic in 108 (32.4%), and transglottic 53 (15.9%) of the the cases. In glottic cancers; cervical metastases were observed in 18.6% of the patients, whereas occult metastases in 11%. In supraglottic cancers; cervical metastasis rate was 45.3% and occult metastases rate was 24%. In transglottic cancers, cervical metastases rate was 49% and occult metastases was 22.6%. Postoperative recurrence was 41 (12.3%). Postoperative radiotherapy was recommended to 111 of 333 patients. The overall survival rate was 75.4% at 50th month and the cumulative survival rate was 68.9%.

Efficacy of N-Acetylcysteine on Wound Healing of Nasal Mucosa.

AbstractPostoperative nasal mucosa healing is a highly complex and organized process, and the success rates of endoscopic sinus surgery and septoplasty surgeries are closely associated with the postoperative wound healing processes. In this experimental study, the authors’ aim was to use histopathologic examination to investigate the effects of N-Acetylcysteine (NAC) on the wound healing of rat nasal mucosa after mechanical trauma. Twenty-one Sprague-Dawley rats were randomly divided into 3 groups: the nontreated group (N = 7), the control saline group (N = 7), and the NAC group (N = 7). No treatment was given to the nontreated group for 15 days. The control saline group received intraperitoneal injection of saline (2.5 mL/kg, intraperitoneal) for 15 days and the NAC group was intraperitoneally injected with NAC at a dose of 300 mg/kg/day for 15 days. At the beginning of the study, unilateral mechanical nasal trauma was induced with an interdental brush inserted through the right nostril in all rats. Samples were stained using hematoxylin and eosin solution, and were examined by a pathologist using a light microscope. The severity of inflammation was milder in the NAC group compared with that in the nontreated and saline groups (P < 0.05). The subepithelial thickness index was lower in the experimental group (P < 0.05). Goblet cell loss was reduced in the experimental group compared with the nontreated and saline groups (P < 0.05). NAC decreases inflammation and goblet cell loss. Therefore, NAC has potential beneficial effects on the wound healing of nasal mucosa in rats.

An Analysis on Aerodynamic and Acoustic Changes After Thyroidectomy

The purpose of this study was to investigate the aerodynamic and acoustic changes after thyroidectomy without laryngeal nerve injury by using objective methods. Voice samples of sustained /α/ recor...

A Case of Pneumorrhachis Due to Disc Degeneration

46 yaşında erkek hasta acil servise aynı gün 2 kez hematemezhematokezya şikayeti olması üzerine başvurdu. Travma hikayesi olmayan hastanın yapılan fizik muayenesi ve laboratuvar bulguları normaldi. Acil olarak yapılan özafagogastroduodenoskopide, özafagial ve fundal varislerin eşlik ettiği pangastrit saptandı. Hastaya yapılan intravenöz kontrastlı abdominal bilgisayarlı tomografide insidental olarak spinal kanalda ve sol nöral foramen düzeyinde ekstraspinal hava habbecikleri izlendi (Resim 1). Sagital reformat görüntüde ise L5-S1 diskinde dejeneratif değişiklikler ve komşu inferior endplate yerleşimli intraspinal hava izlendi (Resim 2). Bu bulgular ile disk dejenarasyonuna sekonder pnömoraşi tanısı konuldu. Resim 2. Sagital reformat görüntüde ise L5-S1 diskinde dejeneratif değişiklikler ve komşu inferior endplate yerleşimli intraspinal hava izlenmektedir (ok). Resim 1. Aksiyel abdominal bilgisayarlı tomografi incelemesinde intraspinal ve sol nöral foramen düzeyinde psoas kası posteriorunda hava izlenmektedir (oklar).

Tinnituslu hastalarda trimetazidin hidroklorür kullanımı sonrasında odyolojik testlerin ve VAS skorlarının karşılaştırılması

Objectives: Although the pathophysiology of tinnitus has not been understood well it is thought to be as a result of anatomical and/or functional change in hearing system. The aim of this study was to compare audiological test results and visual analog scala (VAS) scores after use of trimetazidine hydrocloride in patients with tinnitus.