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Eric Nicolai

Bristol-Myers Squibb

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Publication

Featured researches published by Eric Nicolai.

ChemMedChem | 2009

Development and Validation of a Pharmacophore-Based QSAR Model for the Prediction of CNS Activity

Rafael Gozalbes; Frédérique Barbosa; Eric Nicolai; Dragos Horvath; Nicolas Froloff

A QSAR model for the prediction of CNS activity was developed and validated based on data from an in‐house database of “drug‐like” compounds. The model has demonstrated its applicability for novel chemical structures and its usefulness for the design of CNS‐focused compound libraries.

Archive | 1998

Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics

Eric Nicolai; Jean-Marie Teulon

Journal of Medicinal Chemistry | 2005

G-protein-coupled receptor affinity prediction based on the use of a profiling dataset : QSAR design, synthesis, and experimental validation

Catherine Rolland; Rafael Gozalbes; Eric Nicolai; Marie-France Paugam; Laurent Coussy; Frédérique Barbosa; Dragos Horvath; Frédéric Revah

Archive | 1991

Pyrazole derivatives as angiotensin II-receptor antagonists, process for their preparation and pharmaceutical compositions containing them

Nicole Bru-Magniez; Eric Nicolai; Jean-Marie Teulon

Journal of Medicinal Chemistry | 1993

Synthesis and structure-activity relationships of novel benzimidazole and imidazo[4,5-b]pyridine acid derivatives as thromboxane A2 receptor antagonists

Eric Nicolai; Joel Goyard; Thierry Benchetrit; Jean Marie Charles Teulon; Francois Caussade; Angela Virone; Chantal Delchambre; Alix Cloarec

Archive | 1991

Pyrimidin derivatives, angiotensin II receptor antagonists, their process of preparation and pharmaceutical compositions containing them.

Nicole Bru-Magniez; Jean-Marie Teulon; Eric Nicolai

Journal of Medicinal Chemistry | 1994

Synthesis and SAR studies of novel triazolopyrimidine derivatives as potent, orally active angiotensin II receptor antagonists.

Eric Nicolai; Gerard Cure; Joel Goyard; Maud Kirchner; Jean-Marie Teulon; Annie Versigny; Michele Cazes; Francois Caussade; Angela Virone-Oddos; Alix Cloarec

Archive | 1990

Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present

Nicole Bru-Magniez; Eric Nicolai; Jean-Marie Teulon

Archive | 1991

Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation

Nicole Bru-Magniez; Eric Nicolai; Jean-Marie Teulon

Archive | 1991

Azabenzimidazole derivatives which are thromboxane receptor antagonists

Nicole Bru-Magniez; Eric Nicolai; Jean-Marie Teulon

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Jean-Marie Teulon

Bristol-Myers Squibb

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Alix Cloarec

Bristol-Myers Squibb

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Dragos Horvath

University of Strasbourg

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