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Dive into the research topics where Alix Cloarec is active.

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Featured researches published by Alix Cloarec.


Bioorganic & Medicinal Chemistry Letters | 2000

Novel 3-(4-piperidinylthio)-1H-indoles as potent nonopioid orally active central analgesics

Dominique Potin; Véronique Parnet; Jean-Marie Teulon; Francoise Camborde; Francois Caussade; Joëlle Meignen; Daniel Provost; Alix Cloarec

A series of 3-(4-piperidinylthio)-1H-indoles was synthesized and evaluated in mice in the phenylbenzoquinone(PBQ)-induced writhing and hot plate tests. Most of these compounds are good analgesics with activities comparable to that of morphine. Among them compound 1i (UP 237-61), which has a strong serotonin binding profile, has an interesting antinociceptive activity which is not reversed by naloxone.


Journal of Medicinal Chemistry | 1994

Synthesis and SAR studies of novel triazolopyrimidine derivatives as potent, orally active angiotensin II receptor antagonists.

Eric Nicolai; Gerard Cure; Joel Goyard; Maud Kirchner; Jean-Marie Teulon; Annie Versigny; Michele Cazes; Francois Caussade; Angela Virone-Oddos; Alix Cloarec


Journal of Medicinal Chemistry | 1994

N6-substituted adenosine receptor agonists. Synthesis and pharmacological activity as potent antinociceptive agents

Timur Gungor; Patrice Malabre; Jean-Marie Teulon; Francoise Camborde; Joëlle Meignen; Francoise Hertz; Angela Virone-Oddos; Francois Caussade; Alix Cloarec


Archive | 1998

Pharmaceutical combination with analgesic activity, containing an adenosinergic agonist and a compound selected from opiates, benzodiazepines and nmda antagonists

François Camborde; Alix Cloarec; Timur Gungor; Jean-Marie Teulon


Archive | 1998

Adenosinergic agonist containing pharmaceutical composition with analgesic activity

Francoise Camborde; Alix Cloarec; Timur Gungor; Jean-Marie Teulon


Archive | 1998

Pharmaceutical combination of a cyclooxigenase-2 inhibitor and acetaminophen or an opiate

François Camborde; Alix Cloarec; Eric Nicolai; Jean-Marie Teulon


Archive | 2002

Method for treatment of pain

Francoise Camborde; Alix Cloarec; Charles M. Conway


European Journal of Pharmacology | 1995

In vivo pharmacological characterization of UP 269-6, a novel nonpeptide angiotensin II receptor antagonist

Michele Cazes; Daniel Provost; Annie Versigny; Alix Cloarec


Chemical & Pharmaceutical Bulletin | 1994

Synthesis and Angiotensin II Receptor Antagonist Activity of C-Linked Pyrazole Derivatives

Eric Nicolai; Gerard Cure; Joel Goyard; Maud Kirchner; Jean-Marie Teulon; Annie Versigny; Michele Cazes; Angela Virone-Oddos; Francois Caussade; Alix Cloarec


Archive | 1998

Pharmaceutical combination of a cyclooxygenase-2 inhibitor

François Camborde; Alix Cloarec; Eric Nicolai; Jean-Marie Teulon

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