Eva Hovorková
Charles University in Prague
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Featured researches published by Eva Hovorková.
Clinical Endocrinology | 1999
Cáp J; Aleš Ryška; Rehorková P; Eva Hovorková; Kerekes Z; Pohnetalová D
The rates of sensitivity and specificity of fine needle aspiration biopsy (FNAB) for the diagnosis of thyroid malignancy differ considerably among various reported series. These values are influenced by three factors: (a) whether only clearly positive and negative results are considered, or whether the commonly encountered 10–20% of indeterminate/suspicious ones are included; (b) whether adenomas are considered as neoplasms in one group with carcinomas; and (c) whether only histologically proven cases are used in calculations or whether patients with benign clinical follow‐up are included.
Journal of Pediatric Hematology Oncology | 2014
Filip Gabalec; Ioannis Svilias; Ivana Plasilova; Eva Hovorková; Aler Ryska; Jiri Horacek
In this study, we describe a case of papillary carcinoma in a 15-year-old girl who presented with a hyperfunctioning (hot) thyroid nodule and discuss it in the context of current management guidelines for patients with thyroid nodules. In adults, hot nodules rarely require cytologic or histologic evaluation, and hyperthyroidism is often treated with radioiodine (131I). However, in children and adolescents, the malignancy rate for nodules (both cold and hot) is higher and surgery is often necessary. Surgery may serve as a therapy, as well as a diagnostic tool, to treat hot nodules in children and adolescents.
Endokrynologia Polska | 2016
Filip Gabalec; Libuse Srbova; Markéta Nová; Eva Hovorková; Helena Hornychova; Iva Jakubikova; Aleš Ryška; Jan Cap
INTRODUCTION The relationship between Hashimotos thyroiditis (HT) and thyroid cancer (TC) is controversial. While most surgical studies report a high incidence of malignancy among patients with HT, cytological studies do not. The role of autoantibodies in the incidence of malignancy is unclear. MATERIAL AND METHODS A single-centre retrospective observational study was conducted in patients evaluated for thyroid nodules by US-guided fine-needle aspiration cytology (FNAC) and, if indicated, by surgery. The levels of thyroid-stimulating hormone (TSH) and anti-thyroid antibodies were measured at the time of FNAC. RESULTS Of 4947 patients, 599 (12.1%) were diagnosed with HT. A malignant/suspicious cytological result was found in 14.2% of the patients with HT and in 15.2% of the others. The odds ratio (OR) for malignancy in HT was 0.921 (0.716-1.183, p = 0.51). Of 1603 patients who underwent surgery, differentiated thyroid carcinoma was found in 29.5% of the HT patients and in 15.2% of the others (OR 2.33, 95% confidence interval CI, 1.403-3.854, p < 0,001). Low TSH (< 0.4 mIU/L) decreased the malignancy rate in the entire patient population, both when considering the cytological results and the surgical results. This was not confirmed in the subgroup diagnosed with HT. No relationship was observed between autoantibodies against thyroid peroxidase (ATP) or thyroglobulin (ATG) and malignancy rate. CONCLUSIONS No association between HT and thyroid cancer was observed cytologically; a positive relationship in histological series was caused by selection bias. Low TSH levels decreased the risk of TC in patients with nodular goitre, but this has not been proven in patients with HT.
Colorectal Disease | 2015
Ferko A; Július Örhalmi; Tomáš Dušek; M. Chobola; Eva Hovorková; D. Hadzi Nikolov; Josef Dolejs
A study was carried out to determine the relationship between mesorectal lymph nodal involvement and T stage in a group of patients with a rectal cancer involving less than one‐quarter of the rectal circumference, such as might be selected for local excision.
Jornal Brasileiro De Nefrologia | 2017
Sylva Skalova; Katerina Racická; Marketa Machackova; Eva Hovorková; Miroslav Podhola
Dr. Pinheiro et al. produziram um excelente panorama sobre a sindrome nefrite tubulo-intersticial e uveite (sindrome TINU) em um paciente adulto, em que a uveite precedeu a nefrite (1). Como foi claramente destacado, a sindrome TINU pode surgir na infância ou na idade adulta durante o decurso de manifestacoes agudas de nefrite tubulo-intersticial. Gostariamos de apresentar nossa observacao de sindrome TINU em um adolescente com inflamacao renal cronica. Um rapaz de 14 anos tratado por uveite anterior aguda foi internado [...]
Videosurgery and Other Miniinvasive Techniques | 2014
Ferko A; Július Örhalmi; Tomáš Dušek; Milan Chobola; Eva Hovorková; Dimitar Hadzi Nikolov
Introduction Currently, the predominant question is whether a laparoscopic approach is comparatively radical in comparison with an open access approach, especially in the circumferential resection margin and quality of the completeness of total mesorectal excision. These factors are important in determining the quality of surgical care as well as long-term results of the treatment. Aim This article focuses on the evaluation of circumferential resection margins and on the quality of mesorectal excision of middle and lower rectum tumors. In addition, laparoscopic and open techniques are compared. Material and methods Data were collected prospectively and stored in a rectal cancer registry over a 3-year period. The parameters studied were age, sex, body mass index, localization and topography of the tumor, clinical stage, neoadjuvant chemotherapy and its response, the type of surgery, character of the circumferential and distal margins, quality of the mesorectal excision, pT and pN. Results One hundred and twenty-five patients were chosen for our study. Laparoscopy was performed in 53 operations and a conventional approach was performed in 72 operations. Complete mesorectal excision was achieved in 54.7% of laparoscopic operations versus 44.4% in the conventional technique; partially complete excision was performed in 20.8 and 12.5%, respectively. Incomplete excisions were described in 24.5 and 43.1% (p = 0.085). Positive circumferential margin occurred during laparoscopic surgery in 11 (20.8%) patients, and in the case of conventional resection in 27 (37.5%) patients (p = 0.044). Conclusions Our study showed comparable results between laparoscopic and open access procedures during rectal resection. The results achieved, in particular in the quality of the mesorectal excision and negative circumferential resection margin, show that the laparoscopic approach is comparable to conventional surgical techniques, with an adequate surgical outcome, in the treatment of rectal cancer.
Pathology Research and Practice | 1998
Aleš Ryška; Zoltán Kerekés; Eva Hovorková; Pavel Barton
Pathology & Oncology Research | 2014
Milan Vošmik; Jan Laco; Igor Sirák; Martin Beranek; Eva Hovorková; Hana Vošmiková; Monika Drastíková; Miroslav Hodek; Zdenek Zoul; Karel Odrazka; Jiri Petera
Strahlentherapie Und Onkologie | 2016
Miroslav Hodek; Igor Sirák; Ferko A; Július Örhalmi; Eva Hovorková; Dimitar Hadži Nikolov; Petr Paluska; Jindřich Kopecký; Jiří Petera; Milan Vošmik
Strahlentherapie Und Onkologie | 2016
Miroslav Hodek; Igor Sirák; Ferko A; Július Örhalmi; Eva Hovorková; Hadži Nikolov D; Petr Paluska; Jindřich Kopecký; Jiří Petera; Milan Vošmik