Eyup Yayci

Evaluation of Thyroid Autoimmunity in Gestational Diabetes Mellitus

The aim of our study was to determine if there is any association between autoimmune thyroid diseases in patients with gestational diabetes. A total of 180 healthy pregnant women (control) and 45 pregnant women with gestational diabetes mellitus (study group) were enrolled in the study. We could not determine any association between gestational diabetes mellitus and thyroid autoimmunity in pregnant.

Association of Speculum Lubrication with Pain and Papanicolaou Test Accuracy

Purpose: To determine the effects of lubrication of the vaginal speculum before insertion during a Papanicolaou test on perceived pain and quality of the cytology specimen. Methods: Four hundred eligible women participating in cervical cancer screening and an early detection program were randomized with respect to lubricant gel use before speculum insertion. Perceived pain during speculum insertion and cytology results were assessed in study groups. Results: The mean age of the patients was 45.7 years (range, 23–77 years). Pain score of the NO GEL group was significantly higher than that of the GEL group (2.3 and 1.6, respectively; P < .05). For postmenopausal women, lubricant gel use significantly reduced the pain scores of the participants (P < .05). Cytological interpretations of the Papanicolaou test specimens were comparable among all groups. Conclusions: During the collection of Papanicolaou test specimens, lubrication of the vaginal speculum with a small amount of K-Y Jelly (a water-soluble lubricant gel) decreases the pain associated with insertion of the vaginal speculum among postmenopausal women without obscuring the cytological interpretation of conventional or liquid-based cytology. In women of reproductive age, lubrication of the speculum with K-Y Jelly does not cause a meaningful effect with respect to perceived pain.

Extra-abdominal removal of placenta during cesarean section: a prospective randomized controlled trial of a novel technique.

Abstract Aim: To evaluate intraoperative and early postoperative outcomes of a novel placenta delivery technique; extra-abdominal removal vs. intra-abdominal removal of the placenta during cesarean section (CS). Methods: A total of 210 women delivering by CS at term in a tertiary university hospital between March 2014 and January 2015 were randomized to extra-abdominal removal vs. intra-abdominal removal of the placenta. The women were randomly allocated to the extra- (group 1) or intra-abdominal removal group (group 2) according to random sampling method, where women with even and odd numbers were allocated to intra- and extra-abdominal groups, respectively. The amount of intra-abdominal hemorrhagic fluid accumulation, the duration of operation and estimated blood loss during operation were the primary outcomes. The secondary outcomes included the mean difference between pre- and post-operative hemoglobin and hematocrit levels, the mean postoperative pain score, any additional need of analgesia, postoperative bowel function, postoperative endometritis and wound infections. Results: The amount of aspirated hemorrhagic fluid was significantly higher in the intra-abdominal group compared to the extra-abdominal group (34.6±22.2 mL vs. 9.4±4.8 mL, P<0.001). Mean duration of the operation, intraoperative blood loss, postoperative requirement of additional analgesia, postoperative pain scores, postoperative endometritis or wound infection, and length of hospital stay were not significantly different between the intra- and extra-abdominal placental removal groups. Conclusion: By extra-abdominal removal of the placenta, the accumulation of bloody fluid in the abdominal cavity is significantly less compared to the intra-abdominal removal method, which, in turn, provides avoidance of excessive mounted-gauze use, intra-abdominal manipulations, or iatrogenic trauma.

Measuring ovarian volume during cesarean delivery provides valuable information about future ovarian function and reproductive capacity

Amac: Yumurtalik hacmi insanlarda yumurtalik rezervinin dolayli olarak tahmin edilmesinde kullanilma potansiyeline sahiptir. Bu calismanin amaci term gebeliklerde sezaryen dogum esnasinda olcerek yumurtalik hacmini belirlemek ve yumurtalik hacmini anne yasi ve obstetrik parametreler ile iliskilendirmektedir. Yontem: Sezaryen dogum sirasinda yumurtalik gozlemi yapildi. Her yumurtaligin uc boyutu (en, boy ve derinlik) olculdu ve basitlestirilmis oval yapi formulu ile sag ve sol yumurtalik hacimleri hesaplandi. Bulgular: Toplam olarak, 132 arastirmaya uygun hasta bulundu. Iki-yonlu ANOVA testi (faktorler: Yas grubu ve yumurtalik tarafi) genel olarak sag yumurtalik hacminin daha buyuk oldugunu gosterdi (p 0,05). Ayni zamanda, Sag ve sol yumurtalik hacimleri arasinda onemli ve guclu bir iliski bulundu (r=0,69; p 0,05). Sonuc: Sezaryen dogum ureme doneminde yapilan bir ameliyat oldugu icin, sag ve sol yumurtalik hacimlerinin dogrudan ve dogru bir sekilde degerlendirilmesi ve kayit edilmesi icin iyi bir firsat olabilir. Bulgularimiz sezaryen dogum sirasinda sag yumurtalik hacminin sol yumurtalik hacmine gore daha fazla oldugunu desteklemektedir. Yumurtalik hacimlerinin bilinmesi gelecekte ortaya cikabilecek ureme sorunlarinin cozumlenmesinde onemli bilgi saglayabilir. Yumurtalik hacimleri kucuk olan kadinlara yumurtalik rezervi konusunda taburcu edilmeden once bilgilendirme yapilabilir

PO-0672 Cord Blood Osteocalcine, Leptin And Tnf? Levels In Gestational Diabetic Pregnancies

Aim To compare cord blood osteocalcin, leptin and TNF α levels in gestational diabetic and normal pregnancies. Method 191 deliveries were included in this research. 41 (21.5%) of pregnancies were gestational diabetic and 159 (78.5%) of pregnancies were normal. Cord blood osteocalcin, leptin and TNF α levels were compared. Results There was no significant difference among birth weights (p:0.409), heights (p:0.07), head circumferences (p 0.201), gender (p:0.4), gestational weeks (p:0.201), ponderal index (0.564) between groups. There was no significant difference between groups regarding pregnancy complications. However, hypothyroidism was more common in gestational diabetic group (p:< 0.001). In addition, hypoglycemia was more common in gestational diabetic group (p:0.047). Gestational diabetic group’s cord blood osteocalcin levels were higher than in non diabetic group (p:0.037). Cord blood TNF α (p:0.813) and leptin average levels (p: 0,212) were not statistically different. Osteocalcin, leptin and TNF α levels were not statistically different between boys and girls. Discussion Osteocalcin; originating from bones, increases insulin sensitivity in peripheral organs and insulin secretion. Leptin is known to inhibit insulin and osteocalcin secretion. Osteocalcin level increase in gestational diabetic group, may be related to osteocalcin regulation of blood glucose levels. Cord blood leptin and TNF α levels showed no significant difference between groups, probably due to proper regulation of cord blood glucose levels during gestation.

Gastrointestinal stromal tumor mimicking gynecological mass: A case report

► GISTs do not have a unique appearance on ultrasound examination. ► If a pelvic mass is detected, the possibility of a non-gynecological tumor like GISTs has to be considered.