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Dive into the research topics where F. Edward Roberts is active.

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Featured researches published by F. Edward Roberts.


Tetrahedron Letters | 1995

The behavior of indene oxide in the ritter reaction: A simple route to cis-aminoindanol

Chris H. Senanayake; F. Edward Roberts; Lisa DiMichele; Kenneth M. Ryan; Ji Liu; Bruce S. Foster; Alan W. Douglas; Robert D. Larsen; Thomas R. Verhoeven; Paul J. Reider

Abstract A regio- and stereoselective synthesis of cis-1-aminoindan-2-ol via a Ritter reaction is described.


Tetrahedron Letters | 1996

THE ROLE OF 4-(3-PHENYLPROPYL)PYRIDINE N-OXIDE (P3NO) IN THE MANGANESE-SALEN-CATALYZED ASYMMETRIC EPOXIDATION OF INDENE

Chris H. Senanayake; George B. Smith; Kenneth M. Ryan; Ji Liu; F. Edward Roberts; David L. Hughes; Robert D. Larsen; Thomas R. Verhoeven; Paul J. Reider

Abstract 4-(3-Phenylpropyl)pyridine N-Oxide (P 3 NO) has provided a more active and stable catalytic media for manganese-salen complex 1 in the asymmetric epoxidation of indene.


Tetrahedron Letters | 1995

Regio- and stereocontrolled syntheses of cyclic chiral cis-amino alcohols from 1,2-diols or epoxides

Chris H. Senanayake; Lisa DiMichele; Ji Liu; Kenneth M. Ryan; F. Edward Roberts; Robert D. Larsen; Thomas R. Verhoeven; Paul J. Reider

Abstract The behavior of 1,2-dioxygen derivatives of indane, tetralin, and benzosuberane in acetonitrile-strong acid media is exploited in the regio- and stereocontrolled syntheses of chiral cis-amino alcohols.


Journal of Organic Chemistry | 1994

Efficient Synthesis of Losartan, A Nonpeptide Angiotensin II Receptor Antagonist

Robert D. Larsen; Anthony O. King; Cheng Y. Chen; Edward G. Corley; Bruce S. Foster; F. Edward Roberts; Chunhua Yang; David R. Lieberman; Robert A. Reamer; David M. Tschaen; Thomas R. Verhoeven; Paul J. Reider; Young Sek Lo; Lucius Thomas Rossano; A. Sidney Brookes; David Meloni; James R. Moore; John F. Arnett


Journal of Organic Chemistry | 1963

The Metalation and Alkylation of Mercaptals

William E. Truce; F. Edward Roberts


Archive | 1991

Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno[2,3-b] thiopyran-2-sulfonamide-7,7-dioxide

Thomas J. Blacklock; Todd K. Jones; Edward J. J. Grabowski; David J. Mathre; Julie J. Mohan; Paul Sohar; F. Edward Roberts; Lyndon C. Xavier


Journal of Organic Chemistry | 1963

A Convenient Synthesis of Aromatic and Aliphatic Sodium Sulfinates

William E. Truce; F. Edward Roberts


Archive | 1996

Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps

Barry C. Buckland; Neal Connors; Michel M. Chartrain; Francis P. Gailliot; Randolph Greasham; Barbara Jackey; Brian Heimbuch; Chanyong Lee; Roger Olewinski; F. Edward Roberts; Paul J. Reider; Thomas R. Verhoeven; Chris H. Senanayake


Archive | 1981

Process for removal of homogeneous catalyst group VIII metals from process streams

F. Edward Roberts; Victor J. Grenda


Tetrahedron Letters | 1979

5-benzylthiothiazolone as a protecting reagent for amines

F. Edward Roberts

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