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Dive into the research topics where F. Iranpour is active.

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Featured researches published by F. Iranpour.


Journal of Bone and Joint Surgery-british Volume | 2011

The position and orientation of total knee replacement components: A COMPARISON OF CONVENTIONAL RADIOGRAPHS, TRANSVERSE 2D-CT SLICES AND 3D-CT RECONSTRUCTION

Michael T. Hirschmann; Praveen Konala; F. Amsler; F. Iranpour; Niklaus F. Friederich; Justin Cobb

We studied the intra- and interobserver reliability of measurements of the position of the components after total knee replacement (TKR) using a combination of radiographs and axial two-dimensional (2D) and three-dimensional (3D) reconstructed CT images to identify which method is best for this purpose. A total of 30 knees after primary TKR were assessed by two independent observers (an orthopaedic surgeon and a radiologist) using radiographs and CT scans. Plain radiographs were highly reliable at measuring the tibial slope, but showed wide variability for all other measurements; 2D-CT also showed wide variability. 3D-CT was highly reliable, even when measuring rotation of the femoral components, and significantly better than 2D-CT. Interobserver variability in the measurements on radiographs were good (intraclass correlation coefficient (ICC) 0.65 to 0.82), but rotational measurements on 2D-CT were poor (ICC 0.29). On 3D-CT they were near perfect (ICC 0.89 to 0.99), and significantly more reliable than 2D-CT (p < 0.001). 3D-reconstructed images are sufficiently reliable to enable reporting of the position and orientation of the components. Rotational measurements in particular should be performed on 3D-reconstructed CT images. When faced with a poorly functioning TKR with concerns over component positioning, we recommend 3D-CT as the investigation of choice.


Journal of Bone and Joint Surgery-british Volume | 2008

The anatomical tibial axis RELIABLE ROTATIONAL ORIENTATION IN KNEE REPLACEMENT

Justin Cobb; H. Dixon; Wael Dandachli; F. Iranpour

The rotational alignment of the tibia is an unresolved issue in knee replacement. A poor functional outcome may be due to malrotation of the tibial component. Our aim was to find a reliable method for positioning the tibial component in knee replacement. CT scans of 19 knees were reconstructed in three dimensions and orientated vertically. An axial plane was identified 20 mm below the tibial spines. The centre of each tibial condyle was calculated from ten points taken round the condylar cortex. The tibial tubercle centre was also generated as the centre of the circle which best fitted eight points on the outside of the tubercle in an axial plane at the level of its most prominent point. The derived points were identified by three observers with errors of 0.6 mm to 1 mm. The medial and lateral tibial centres were constant features (radius 24 mm (SD 3), and 22 mm (SD 3), respectively). An anatomical axis was created perpendicular to the line joining these two points. The tubercle centre was found to be 20 mm (SD 7) lateral to the centre of the medial tibial condyle. Compared with this axis, an axis perpendicular to the posterior condylar axis was internally rotated by 6 degrees (SD 3). An axis based on the tibial tubercle and the tibial spines was also internally rotated by 5 degrees (sd 10). Alignment of the knee when based on this anatomical axis was more reliable than either the posterior surfaces or any axis involving the tubercle which was the least reliable landmark in the region.


Knee Surgery, Sports Traumatology, Arthroscopy | 2010

A novel standardized algorithm for evaluating patients with painful total knee arthroplasty using combined single photon emission tomography and conventional computerized tomography

Michael T. Hirschmann; F. Iranpour; Praveen Konala; Anna Kerner; Helmut Rasch; Justin Cobb; Niklaus F. Friederich

SPECT/CT is a promising diagnostic modality in patients with painful total knee arthroplasty (TKA). The purpose of this study is to introduce a novel standardized SPECT/CT algorithm and evaluate its clinical application and reliability. A novel SPECT/CT localization scheme consisting of 9 tibial, 9 femoral and 4 patellar regions on standardized axial, coronal and sagittal slices is proposed. It was piloted in 18 consecutive patients with post TKA pain. The tracer activity on SPECT/CT was recorded using a color-coded scale (0–10). The inter- and intra-observer reliability was assessed for localization and tracer activity. The prosthetic component position was assessed in the CT images after 3D reconstruction using standardized frames of reference. The median inter- and intra-observer differences and ranges of the measured angles were calculated along with the ICC values for inter- and intra-observer reliability. The localization scheme showed very high inter- and intra-observer reliabilities for all regions. The measurement of component position was highly reliable in all cases with sufficient visibility of anatomical landmarks. The median inter-observer difference between alignment measurements for tibial and femoral components was less than 3° (range 0°–6°). The median intra-observer variability for these was less than 2° (range 0°–5°). The SPECT/CT algorithm presented is both reliable and useful in the management of patients with painful TKA. It combines biomechanical and metabolic data (tracer localization) providing an extra dimension to the understanding of this difficult condition. The clinical value of SPECT/CT in patients with unexplained pain following TKA should be further investigated.


BMC Musculoskeletal Disorders | 2011

Clinical value of SPECT/CT for evaluation of patients with painful knees after total knee arthroplasty- a new dimension of diagnostics?

Michael T. Hirschmann; Praveen Konala; F. Iranpour; Anna Kerner; Helmut Rasch; Niklaus F. Friederich

BackgroundThe purpose of our study was to evaluate the clinical value of hybrid SPECT/CT for the assessment of patients with painful total knee arthroplasty (TKA).MethodsTwenty-three painful knees in patients following primary TKA were assessed using Tc-99m-HDP-SPECT/CT. Rotational, sagittal and coronal position of the TKA was assessed on 3D-CT reconstructions. The level of the SPECT-tracer uptake (0-10) and its anatomical distribution was mapped using a validated localization scheme. Univariate analysis (Wilcoxon-Mann-Whitney, Spearmean`s-rho test, p < 0.05) was performed to identify any correlations between component position, tracer uptake and diagnosis.ResultsSPECT/CT imaging changed the suspected diagnosis and the proposed treatment in 19/23 (83%) knees. Progression of patellofemoral OA (n = 11), loosening of the tibial (n = 3) and loosening of the femoral component (n = 2) were identified as the leading causes of pain after TKA.Patients with externally rotated tibial trays showed higher tracer uptake in the medial patellar facet (p = 0.049) and in the femur (p = 0.051). Patients with knee pain due to patellofemoral OA showed significantly higher tracer uptake in the patella than others (p < 0.001).ConclusionsSPECT/CT was very helpful in establishing the diagnosis and guiding subsequent management in patients with painful knees after TKA, particularly in patients with patellofemoral problems and malpositioned or loose TKA.


Clinical Orthopaedics and Related Research | 2010

The geometry of the trochlear groove.

F. Iranpour; Azhar M. Merican; Wael Dandachli; Andrew A. Amis; Justin Cobb

BackgroundIn the natural and prosthetic knees the position, shape, and orientation of the trochlea groove are three of the key determinants of function and dysfunction, yet the rules governing these three features remain elusive.Questions/PurposeThe aim was to define the three-dimensional geometry of the femoral trochlea and its relation to the tibiofemoral joint in terms of angles and distances.MethodsForty CT scans of femurs of healthy patients were analyzed using custom-designed imaging software. After aligning the femur using various axes, the locations and orientations of the groove and the trochlear axis were examined in relation to the conventional axes of the femur.ResultsThe trochlear groove was circular and positioned laterally in relation to the mechanical, anatomic, and transcondylar axes of the femur; it was not aligned with any of these axes. We have defined the trochlear axis as a line joining the centers of two spheres fitted to the trochlear surfaces lateral and medial to the trochlear groove. When viewed after aligning the femur to this new axis, the trochlear groove appeared more linear than when other methods of orientation were used.ConclusionsOur study shows the importance of reliable femoral orientation when reporting the shape of the trochlear groove.


Knee Surgery, Sports Traumatology, Arthroscopy | 2010

Combined single-photon emission computerized tomography and conventional computerized tomography (SPECT/CT): clinical value for the knee surgeons?

Michael T. Hirschmann; F. Iranpour; Kinner Davda; Helmut Rasch; Rolf Hügli; Niklaus F. Friederich

Single-photon emission computerized tomography in combination with conventional computer tomography (SPECT/CT) is an emerging technology that may hold great clinical value to the orthopaedic knee surgeon. Post-operative knee pain is a familiar condition seen in most orthopaedic clinics. Here, we present the value of SPECT/CT in three such cases of pain after surgical treatment of knee osteoarthritis (high tibial osteotomy, medial unicompartmental arthroplasty, total knee arthroplasty). In these patients with post-operative knee pain, SPECT/CT has proved to be beneficial in establishing the diagnosis and providing guidance for further treatment.


Journal of Orthopaedic Research | 2009

Patellofemoral joint kinematics: the circular path of the patella around the trochlear axis.

F. Iranpour; Azhar M. Merican; Ferdinando Rodriguez y Baena; Justin Cobb; Andrew A. Amis

Differing descriptions of patellar motion relative to the femur have resulted from previous studies. We hypothesized that patellar kinematics would correlate to the trochlear geometry and that differing descriptions could be reconciled by accounting for differing alignments of measurement axes. Seven normal fresh‐frozen knees were CT scanned, and their kinematics with quadriceps loading was measured by an optical tracker system. Kinematics was calculated in relation to the femoral epicondylar, anatomic, and mechanical axes. A novel trochlear axis was defined, between the centers of spheres best fitted to the medial and lateral trochlear articular surfaces. The path of the center of the patella was circular and uniplanar (root‐mean‐square error 0.3 mm) above 16 ± 3° (mean ± SD) knee flexion. In the coronal plane, this circle was aligned 6 ± 2° from the femoral anatomical axis, close to the mechanical axis alignment. It was 91 ± 3° from the epicondylar axis, and 88 ± 3° from the trochlear axis. In the transverse plane it was 91 ± 3° and 88 ± 3° from the epicondylar and trochlear axes, respectively. Manipulation of the data to different axis alignments showed that differing previously published data could be reconciled. The circular path of patellar motion around the trochlea, aligned with the mechanical axis of the leg, is easily visualized and understood.


Journal of Biomechanics | 2009

The structural properties of the lateral retinaculum and capsular complex of the knee

Azhar M. Merican; Sanjay Sanghavi; F. Iranpour; Andrew A. Amis

Although lateral retinacular releases are not uncommon, there is very little scientific knowledge about the properties of these tissues, on which to base a rationale for the surgery. We hypothesised that we could identify specific tissue bands and measure their structural properties. Eight fresh-frozen knees were dissected, and the lateral soft tissues prepared into three distinct structures: a broad tissue band linking the iliotibial band (ITB) to the patella, and two capsular ligaments: patellofemoral and patellomeniscal. These were individually tensile tested to failure by gripping the patella in a vice jaw and the soft tissues in a freezing clamp. Results: the ITB–patellar band was strongest, at a mean of 582 N, and stiffest, at 97 N/mm. The patellofemoral ligament failed at 172 N with 16 N/mm stiffness; the patellomeniscal ligament failed at 85 N, with 13 N/mm stiffness. These structural properties suggest that most of the load in-vivo is transmitted to the patella by the transverse fibres that originate from the ITB.


Journal of Bone and Joint Surgery, American Volume | 2008

Learning How to Resurface Cam-Type Femoral Heads with Acceptable Accuracy and Precision: The Role of Computed Tomography-Based Navigation

Justin Cobb; Vijayaraj Kannan; Wael Dandachli; F. Iranpour; Klaus U. Brust; A. J. Hart

BACKGROUND Resurfacing arthroplasty for cam-type deformities, which are a common cause of early osteoarthritis, is a technically demanding operation. Like any other arthroplasty, it requires both accuracy and precision. On the basis of the results of series reported by expert surgeons, we considered it desirable that this operation should be performed within +/-10 degrees of the desired angular orientation and +/-6 mm of entry-point translation in 95% of hips. Technological aids are now available to help surgeons achieve that level of accuracy. Three models of cam-type hips of increasing severity were used to assess the efficacy of three systems of instrumentation at delivering the required level of accuracy and precision. METHODS Thirty-two students of surgical technology were instructed in hip resurfacing and shown detailed plans of the desired operative outcome for the three hips with cam-type deformity. They then used conventional instruments, imageless navigation, and computed tomography-based navigation to perform the operation as accurately as possible. RESULTS Conventional instrumentation produced an unacceptably wide range of entry-point errors. Imageless navigation was able to deliver adequate accuracy and precision in varus-valgus angulation and superoinferior translation, but was less satisfactory in version and anteroposterior translation. Computed tomography-based navigation enabled novice surgeons to navigate hips that had difficult cam-type deformity with acceptable precision in all four degrees of freedom measured. CONCLUSIONS Only computed tomography-based navigation appears to be appropriate for delivering both the accuracy and the precision needed by surgeons on the steep part of their learning curve. Neither conventional neck-based instrumentation nor imageless navigation provided enough help for novice surgeons learning to perform this technically challenging operation.


International Orthopaedics | 2011

Combined single photon emission computerised tomography and conventional computerised tomography (SPECT/CT) in patellofemoral disorders: a clinical review

Michael T. Hirschmann; Kinner Davda; F. Iranpour; Helmut Rasch; Niklaus F. Friederich

Patellofemoral disorders are common conditions seen in a knee clinic but can present a great diagnostic challenge to the orthopaedic surgeon. Combined single photon emission computerised tomography with conventional computer tomography (SPECT/CT) provides the clinician with precise anatomical and physiological information of the patellofemoral joint. We present a clinical review that highlights the value of SPECT/CT in patients with patellofemoral disorders, where other modalities such as radiographs, MRI, and conventional CT did not provide sufficient information. SPECT/CT has proven to be helpful for establishing the diagnosis and guidance for further treatment. SPECT/CT should be recognised as a valuable diagnostic tool in orthopaedic patients.

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Justin Cobb

Imperial College London

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E. Auvinet

Imperial College London

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C. Rivière

Imperial College London

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A. Aframian

Imperial College London

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S. Harris

Imperial College London

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