Fabien Louis Cabirol
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Publication
Featured researches published by Fabien Louis Cabirol.
Angewandte Chemie | 2018
Feng Xu; Birgit Kosjek; Fabien Louis Cabirol; Haibin Chen; Richard Desmond; Jeonghan Park; Anupam Gohel; Steven J. Collier; Derek Smith; Zhuqing Liu; Jacob M. Janey; John Y. L. Chung; Oscar Alvizo
Described here is an efficient stereoselective synthesis of vibegron enabled by an enzymatic dynamic kinetic reduction that proceeds in a high-pH environment. To overcome enzyme performance limitations under these conditions, a ketoreductase was evolved by a computationally and structurally aided strategy to increase cofactor stability through tighter binding.
Archive | 2011
Fabien Louis Cabirol; Anupam Gohel; Seong Ho Oh; Derek Smith; Brian Wong; James Lalonde
Archive | 2011
Fabien Louis Cabirol; Steven J. Collier; Thomas Daussmann; Naga K. Modukuru
Archive | 2012
Fabien Louis Cabirol; Haibin Chen; Anupam Gohel; Steven J. Collier; Derek Smith; Birgit Kosjek; Jacob Janey
Archive | 2013
Haibin Chen; Yong Koy Bong; Fabien Louis Cabirol; Anupam Gohel; Tao Li; Jeffrey C. Moore; Martina Quintanar-Audelo; Hong Yang; Steven J. Collier; Derek Smith
Archive | 2011
John Limanto; Gregory Beutner; Brendan Grau; Jacob Janey; Artis Klapars; Eric R. Ashley; Hallena R. Strotman; Matthew D. Truppo; Gregory Hughes; Fabien Louis Cabirol; Anupam Gohel; Steven J. Collier; Jack Liang; Marissa Mock; Emily Mundorff; Scott Novick; Derek Smith
Archive | 2012
Fabien Louis Cabirol; Haibin Chen; Anupam Gohel; Paulina Salim; Derek Smith; Jacob Janey; Birgit Kosjek; Weng Lin Tang; Helen Hsieh; Son Pham
Archive | 2013
Haibin Chen; Yong Koy Bong; Fabien Louis Cabirol; Anupam Gohel Prafulchandra; Tao Li; Jeffrey C. Moore; Martina Quintanar-Audelo; Yang Hong; Steven J. Collier; Derek Smith
Archive | 2011
Fabien Louis Cabirol; Anupam Gohel; Seong Ho Oh; Derek Smith; Brian Wong; James Lalonde
Archive | 2011
Fabien Louis Cabirol; Anupam Gohel; Steven J. Collier; Jack Liang; Marissa Mock; Emily Mundorff; Scott Novick; John Limanto; Derek Smith; Gregory L. Beutner; Artis Klapars; Eric R. Ashley; Hallena Strotman; Matthew D. Truppo; Gregory Hughes; Brendan Grau; Jacob Janey
