Fabio Zangrandi
University of Padua
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Publication
Featured researches published by Fabio Zangrandi.
Obesity Surgery | 2003
Paolo Bernante; Francesco Francini; Fabio Zangrandi; Paola Menegon; Antonio Toniato; Paolo Feltracco; Maria Rosa Pelizzo
Background: The intragastric balloon is filled with saline and methylene blue dye, to detect balloon deflation early and prevent bowel obstruction, by monitoring the patients urine for changes in color. Methods: An intragastric balloon filled with 590 ml of saline plus 10 ml of methylene blue was endoscopically placed under sedation in a 22-year-old man with morbid obesity (BMI 42 kg/m2). 3 days later, the patients urine changed to dark green, and, suspecting a leaking balloon, endoscopy was repeated under sedation. Results: No signs of balloon deflation were seen, and the urine returned to normal color. The next day, the urine turned green again. 7 days later, the urine discoloration finally disappeared. Conclusion: Propofol, a sedative commonly used by anesthesiologists during endoscopic procedures, is known to have several side-effects, and urine discoloration is one of them, albeit rare. This benign side-effect must be known to obesity surgeons to avoid pointless medical expenditure, unnecessary balloon removal and distress for patients and clinicians.
American Journal of Surgery | 1990
Alvise Maffei-Faccioli; Giorgio Enrico Gerunda; Daniele Neri; Roberto Merenda; Fabio Zangrandi; F. Meduri
Seventy patients, selected from 265 patients with proved variceal bleeding, underwent a distal splenorenal shunt (DSRS) procedure with or without splenopancreatic disconnection (SPD). Alcoholic cirrhosis was the cause of portal hypertension in 57% of the patients. The operative mortality was 13% (Childs classes A and B 2%, class C 66%). Despite fewer varices in all of the patients, variceal rebleeding and death occurred in one patient (2%). Late portal perfusion was observed in 91% of the patients, with worsening in 23%, compared with the preoperative study. Persistent hepatocyte necrosis and incomplete SPD were the most significant prognostic factors for decreased perfusion (presence and absence of necrosis, 38% and 12%, respectively; DSRS and DSRS with SPD, 43% and 12%, respectively). SPD also decreased ongoing hepatocyte damage. Post-shunt encephalopathy was clinically evident in 7% of the patients, but after electroencephalographic evaluation, it increased to 24.6%. Significant factors in its development included decreased portal perfusion (62% versus 14%), active hepatitis (48% versus 17%), and incomplete SPD (43% versus 14%). The higher late liver-related mortality was associated with a lack of or decreased portal perfusion and the absence of SPD.
Obesity Surgery | 2005
Paolo Bernante; Francesco Francini Pesenti; Antonio Toniato; Fabio Zangrandi; Fabio Pomerri; Maria Rosa Pelizzo
Background: For some patients, especially those with a higher BMI, a non-selective Lap-Band® placement using the pars flaccida approach with application of the small-diameter bands (9.75 and 10 cm) may be too tight or may require significant gastroesophageal junction dissection and thinning. In such a case, the major perioperative complication is acute obstruction immediately after surgery. We review the etiology of obstructive complications that present postoperatively in the first 24 hours. Case Reports: Acute postoperative stoma obstruction (esophageal outlet stenosis) was observed in 5 patients who underwent 9.75-cm Lap-Band® placement for morbid obesity. 2 of these patients had a postoperative upper GI series showing a misplaced band with gastric slippage, and repeat operation was required. 3 patients had gastric obstruction without slippage. Of the latter, 1 patient insisted that the band be removed rather than being replaced with a longer one, and the remaining 2 were managed with conservative treatment, involving extended hospitalization until the edema subsided and the patient slowly regained the ability to swallow. Conclusion: Obstructive symptoms associated with the Lap-Band® using the pars flaccida approach can be addressed conservatively in most patients or by minimally invasive surgery; however we believe that routine use of the 11-cm Lap-Band® for the pars flaccida approach could easily prevent this early complication.
Transplantation | 2002
Giorgio Enrico Gerunda; Roberto Merenda; Daniele Neri; Franco Barbazza; Paolo Angeli; David Sacerdoti; Diego Miotto; Fabio Zangrandi; Antonio Gangemi; Alvise Maffei Faccioli
Background. Fistulous communications between the accessory right hepatic (ARHA), gastroduodenal (GD), and superior mesenteric (SMA) arteries and the portal vein (PV) may represent a contraindication for liver transplantation (LT). Material. A patient with HCV-related liver cirrhosis and progressive liver decompensation underwent preoperative LT work-up. Doppler ultrasound (DU), Angiography and MRI revealed arteroportal fistulas (APF) and diversion of mesenteric-splenoportal flow through spontaneous splenorenal shunts (SSRS) in the systemic circulation. The patient was transplanted and the ARHA and GDA were distally sectioned; the HA was anastomosed to the donor HA; the superior mesenteric vein (SMV) was detached from the splenopancreatic venous bed by sectioning and ligating the Henle trunk, by ligating an posterior-inferior pancreatic vein and, finally, by positioning an iliac vein interposition graft between the SMV and the donor PV. The postanastomotic SMV trunk and recipient PV were ligated below and above the pancreatic head, respectively. Results. Reperfusion and late liver function were good. DU and MRI studies showed an effective portal flow and the maintenance of a normal splenopancreatic vein outflow through the SSRS. Discussion. APF represent a serious clinical problem, particularly in patients who need LT. The persistence of arterial flow into the PV is dangerous for the long-term liver function. A particular surgical strategy, strictly tailored to the hemodynamic conditions, has to be planned. Conclusions. Extrahepatic multiple APF would no longer to represent a contraindication to LT, although this claim needs to be confirmed in the light of further experience and a longer-term follow-up.
Liver Transplantation | 2000
Giorgio Enrico Gerunda; Daniele Neri; Roberto Merenda; Franco Barbazza; Fabio Zangrandi; F. Meduri; Marco Bisello; Antonio Gangemi; Alvise Maffei Faccioli
Liver Transplantation | 2002
Giorgio Enrico Gerunda; Roberto Merenda; Daniele Neri; Paolo Angeli; Franco Barbazza; Paolo Feltracco; Fabio Zangrandi; Antonio Gangemi; Diego Miotto; Alessandro Gagliesi; Alvise Maffei Faccioli
British Journal of Surgery | 1992
P. Prandoni; F. Meduri; S. Cuppini; A. Toniato; Fabio Zangrandi; P. Polistena; F. Gianese; A. Maffei Faccioli
Obesity Surgery | 2008
Paolo Bernante; Cristiano Breda; Fabio Zangrandi; Fabio Pomerri; Maria Rosa Pelizzo; Mirto Foletto
Hepato-gastroenterology | 2002
Giorgio Enrico Gerunda; Massimo Bolognesi; Daniele Neri; Roberto Merenda; Diego Miotto; Franco Barbazza; Fabio Zangrandi; Marco Bisello; Antonio Gangemi; Alessandro Gagliesi; Alvise Maffei Faccioli
Canadian Journal of Surgery | 2009
Fabio Zangrandi; Andrea Piotto; Alberto Tregnaghi; Maria Rosa Pelizzo