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Dive into the research topics where Fabrizio De Biasio is active.

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Featured researches published by Fabrizio De Biasio.


Journal of Oral and Maxillofacial Surgery | 2008

Full-Thickness Lower Eyelid Reconstruction With a Conchal Chondro-Perichondral Graft and Local Coverage With Mio-Cutaneous Flaps—Our Divisional Experience

Pier Camillo Parodi; Gianpaolo Faini; Fabrizio De Biasio; Emanuele Rampino Cordaro; Gianni Franco Guarneri; Flavia Miani

BACKGROUND Eyelid reconstruction represents a challenge because of the complexity of this structure. Full-thickness eyelid defects demand the reconstruction of 2 fundamental elements: anterior and posterior lamellae. The available reconstructive techniques are all associated with the attention to restore the support and responsibility of eyelid stability, represented physiologically by the tarsus. In 1987, Matsuo proposed a reconstructive technique that involved the use of a chondro-perichondral graft harvested from the auricular concha to reconstruct the posterior lamella, and an adjacent skin flap to restore the anterior lamella. MATERIALS AND METHODS We report our divisional experience of a series of 28 patients operated on from 2000 to 2004, whose eyelid restoration was achieved with the use of Matsuos technique modified with the purpose to avoid complications such as ectropion or lagophtalmus. RESULTS All the grafts survived, and no major complication such as ectropion or lagophthalmos has been detected. Our specialistic judgment has ranged from good to excellent regarding symmetry, eyelid closure, and donor site morbidity. Patients were entirely satisfied with the functional result obtained, and generally with the esthetic outcome also, judged as ranging from good to extremely satisfactory. CONCLUSIONS The success of eyelid reconstruction using modified Matsuos technique depends, in our minds, on an adequate knowledge of traditional eyelid reconstruction methods, and on a few technical fine points that help to reduce postoperative complications and to optimize the quality of the end result; hence, this technique has become the gold standard in lower eyelid reconstruction in our division.


Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery | 2003

The distally-based radial fasciosubcutaneous flap for soft tissue cover of the flexor aspect of the wrist.

Pier Camillo Parodi; Fabrizio De Biasio; Emanuele Rampino; Jacopo Tesei; Nicola Panizzo

The distally-based radial forearm fasciosubcutaneous flap is based on the distal perforators of the radial artery. We used it in a particularly difficult case involving loss of soft tissue at the wrist with exposure of tendons and nerves after an operation to section the transverse carpal ligament for carpal tunnel syndrome complicated by a chronic fistula.


Annals of Plastic Surgery | 2003

Desmoplastic melanoma of the nail.

Piercamillo Parodi; Cathryn Anne Scott; Fabrizio De Biasio; Ilaria Pezzini; Barbara Pertoldi; Carlo Alberto Beltrami

Desmoplastic melanoma represents a variant of melanoma that is difficult to diagnose because 71% of patients have amelanotic skin lesions. In the acral region of the limbs, the clinical diagnosis is more difficult, especially in cases in which there are not clear, rapidly growing, pigmented nail streaks. Histopathological identification of desmoplastic melanoma is confusing because of the intense fibrous reaction in the dermis and minimal, atypical melanocytic proliferation at the dermal-epidermal junction. For these reasons, it is still misdiagnosed unfortunately as a variety of entities, including simple scar, fibrohistiocytic neoplasms, neural tumors, and superficial fibromatoses-with potentially devastating consequences. In equivocal cases, the use of immunohistochemistry (in particular S-100 and neuron-specific enolase) may be helpful in establishing the diagnosis. Because of the high local recurrence rate for desmoplastic melanoma of the finger, amputation is recommended in an effort to gain effective tumor control. Lymph node dissection may be reserved for patients with positive axillary nodes.


Journal of Plastic Surgery and Hand Surgery | 2010

Distally-based superficial sural flap: advantages of the adipofascial over the fasciocutaneous flap.

Pier Camillo Parodi; Fabrizio De Biasio; Emanuele Rampino Cordaro; Gianni Franco Guarneri; Nicola Panizzo; Carlo Riberti

Abstract The distally-based superficial sural flap has proved to be an easy and reliable method of reconstruction in soft tissue cover of the distal third part of the leg. There are two ways to prepare this flap: as a fasciocutaneous flap, which includes the fascia with the subcutaneous tissue including the skin; or as an adipofascial flap, which is made up of both the fascia and the subcutaneous adipose tissue. In the latter case, the flap is covered with a partial thickness skin graft either immediately after or at a later stage. The aim of this study was to assess the advantages and disadvantages of the two flaps. The adipofascial flap seems to be better, as it is associated with less donor site morbidity, improved quality of reconstruction, and fewer complications.


BioMed Research International | 2013

Lower Lid Reconstruction Utilizing Auricular Conchal Chondral-Perichondral Tissue in Patients with Neoplastic Lesions

Pier Camillo Parodi; Fabrizio Calligaris; Fabrizio De Biasio; Giovanna De Maglio; Flavia Miani; Marco Zeppieri

Purpose. To assess surgical outcomes of lower lid reconstruction surgery using auricular conchal tissue. Methods. This prospective study included 20 patients that underwent reconstructive lower lid surgery using autologous auricle chondral-perichondral graft tissue. Auricle tissue was used to provide adequate support and protection with similar conjunctiva tarsal structures on overlying soft tissues in patients with pathologic inferior lid tissue loss requiring reconstructive surgery. Biopsies with histopathology and cytology analysis were taken after 1 year. Cytology analysis using CK19 was used to confirm newly formed conjunctiva overlying the graft. Results. All patients showed no graft rejection. Surgical outcomes were generally good, with minimal or no ocular complications. 16 of 20 patients had excellent results, showing good lid symmetry and esthetics, minimal auricular discomfort, patient satisfaction and proper lid function. Surgical outcomes were highly dependent on proper post-op conjunctiva formation. All patients were positive for CK19, thus indicating proper conjunctiva tissue formation. Conclusions. Lower lid reconstruction surgery using auricular chondral-perichondral conchal tissue is a good alternative in patients with neoplastic lesions. Autologous chondral-perichondral tissue provides good functional and mechanical support in the reconstructed lid, thus reducing the risks of ectropion and corneal exposure and ensuring a protected ocular surface.


Indian Journal of Plastic Surgery | 2017

A new method of salvaging nipple projection after secondary nipple reconstruction using locoregional flap

Fabrizio De Biasio; Nicola Zingaretti; Sebastiano Mura; Alessandra Fin; Michele Riccio; Pier Camillo Parodi

Sir, The most important features of a natural reconstructed nipple are symmetry and a durable valid vertical projection. A frequent drawback of the methods currently used for nipple reconstruction is the loss of nipple projection in the longer post‐operative term. Although numerous nipple‐areolar complex reconstruction techniques have been described,[1‐3] common among these techniques is a failure to maintain a nipple projection over time (estimated at 17%–75%), and difficulties related to maintenance of nipple projection have been well documented.[4]


Orbit | 2018

Posterior lamellar reconstruction: a comprehensive review of the literature

Alessandra Fin; Fabrizio De Biasio; Paolo Lanzetta; Sebastiano Mura; Anna Tarantini; Pier Camillo Parodi

ABSTRACT The aim of the review is to describe the different techniques and materials available to reconstruct the tarsoconjunctival layer of the eyelid; to analyze their indications, advantages, and disadvantages. We searched the Cochrane, PubMed, and Ovid MEDLINE databases for English articles published between January 1990 and January 2017 using variations of the following key words: “posterior lamella,” “eyelid reconstruction,” “tarsoconjunctival,” “flap,” and “graft.” Two reviewers checked the abstracts of the articles found to eliminate redundant or not relevant articles. The references of the identified articles were screened manually to include relevant works not found through the initial search. The search identified 174 articles. Only a few articles with a therapeutic level of evidence were found. Techniques for the posterior lamellar reconstruction can be categorized as local, regional, and distant flaps; tarsoconjunctival, heterotopic, homologous, and heterologous grafts. Several techniques and variations on the techniques exist to reconstruct the posterior lamella, and, for similar indications, there’s no evidence of the primacy of one over the other. Defect size and location as well as patient features must guide the oculoplastic surgeon’s choice. The use of biomaterials can avoid possible complications of the donor site.


Advances in Clinical and Experimental Medicine | 2018

Surgical and oncological outcomes of free dermal fat graft for breast reconstruction after breast-conserving surgery

Fabrizio De Biasio; Serena Bertozzi; Ambrogio P. Londero; Daria Almesberger; Chiara Zanin; Andrea Marchesi; Carla Cedolini; Andrea Risaliti; Pier Camillo Parodi

BACKGROUND Oncoplastic breast surgery originated in order to improve the esthetic result of breast-conserving surgery (BCS). Autologous free dermal fat graft (FDFG) is an emerging oncoplastic technique to improve the cosmetic outcome of breast-conserving surgery. OBJECTIVES The aim of this study was to analyze our experience with FDFGs in breast reconstruction after breast-conserving surgery. Oncological outcomes, surgical complications and cosmetic results were considered. MATERIAL AND METHODS This retrospective chart review study considered all consecutive oncoplastic breast treatment by means of FDFG reconstruction during the period between September 2011 and September 2012 in our Clinic of Surgery (University of Udine, Italy). The data collected included patient and tumor characteristics and outcomes (cosmetic and oncological). RESULTS During the study period, 37 women were treated by breast cancer surgery and immediate breast reconstruction by FDFG. At a 3-year follow-up, we found no cases of recurrence among breast cancer patients treated by FDFG; at a 18-month follow-up, we found a prevalence of 75.0% of women extremely satisfied with their oncoplastic surgery and a high prevalence of excellent or good cosmetic outcomes (70.3%) according to objective and subjective cosmetic assessment. CONCLUSIONS Immediate breast reconstruction by FDFG after BCS in a population selected for a low risk of breast cancer recurrence seems to be an oncologically safe option, with a good cosmetic outcome and a high prevalence of women satisfied with the treatment.


The Pan African medical journal | 2017

A case of gestational gigantomastia in a 37-years-old woman associated with elevated ANA: a casual linkage?

Nicola Zingaretti; Fabrizio De Biasio; Michele Riccio; Nastassia Nardini; Laura Mariuzzi; Pier Camillo Parodi

Hypertrophy of the breast (macromastia and gigantomastia) is a rare medical condition of the breast connective tissues. The etiology of this condition is still not clear; rarely, gigantomastia has been reported to develop in the setting of an autoimmune illness. We reported a case of a 37-years-old woman with undifferentiated connective tissue disease of 2-years duration presented with enlargement of breasts. The breast enlargment started at 5 months of gestation. She successfully underwent reduction mammoplasty with free nipple graft. In the succeeding months the level of antinuclear ANA remained stable. It is uncertain whether a positive antinuclear antibodies in gigantomastia is a casuative agent or an effect.


Journal of Craniofacial Surgery | 2017

An Efficient Method for Hair Containment During Head and Neck Surgery

Nicola Zingaretti; Fabrizio De Biasio; Michele Riccio; Andrea Marchesi; Pier Camillo Parodi

The authors present a simple technique for operations around hair-bearing areas such as during a rhytidectomy. Hair surrounding the surgical field is twisted into bundles and clipped with duckbill clips. The authors repeat the procedure for each strand of hair. Between 5 and 7 duckbill clips may be required per surgery.The clippers are faster, easily applicable, and well performing. They can be used with different hair lengths, and they do not require any additional trimming or shaving; clips also keep the hair firmly in place, and they do not loosen up in the process.This technical note explains a very simple, economical, and less time-consuming method to control hair located around the surgical site. It may be applied to all procedures within the field of the hair-bearing scalp, including craniofacial and maxillofacial surgery.

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Francesca De Lorenzi

European Institute of Oncology

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