Farida Tabri

A Comparison Between 0,25% Tumeric Extract Cream and Grated Tumeric for Skin Discoloration

Turmeric has been found to have some efficacies in repairing the skin texture including its ability to enlighten the color of the skin associated to premature skin aging. This study aims to compare between the 0.25% turmeric extract cream and grated turmeric in skin color change. Samples in this study were collected from women subjects that were selected randomly and consecutively. There were 22 women subjects involved in this study that were assigned into two treatment groups: group I with one application a day and group II with two applications a day. Each subject in both groups applied 0.25% turmeric extract cream in upper right arm, control (4% Hydroquinone) in lower right and left arms, and grated turmeric in upper left arm. The treatment responses were evaluated by skin analyzer measuring the pigment number at day 0, 8, and 21. Data were analyzed statistically by Willcoxon test. Study findings indicated significant differences (p<0,05) between twice application of 0. 25% turmeric cream extract and 4% Hq at day 8 (2.30) on skin changes (pigment). There was also a significant difference (p<0,05) when comparing the 0,25 turmeric extract in twice application a day between H21-H0 and H21-H8.

The Effect of Softener in Polyester Textile Fibers to the Pruritus Response and Erythema with Atopic Dermatitis Patients

Atopic dermatitis is a chronic skin disease that most commonly occurs in children. This study aimed to assess the effective of softener on polyester textile material on the pruritus degree and erythema of patients with atopic dermatitis. The research was conducted at Senior High School 17 of Makassar. The method used was clinical test with experimental design to determine the role of softener on pruritus response of patients with atopic dermatitis. The sample consisted of 50 people given fabric softener material on the right and without softener on the left arms. Two hours and twenty four hours later the degree of pruritus and erythema was measured. The results of the research indicate that the use of softener on polyester textile increases the degree of pruritus and erythema.

Effect of Doxycycline in Autologous Serum to Improvement Clinical Manifestation of Acne Vulgaris

Acne vulgaris (AV) is an inflammatory disease of skin on the follicle polisebasea frequent and considered dermatological problems the most common worldwide. This study investigates the relationship topical therapy using autologous serum containing doxycycline in women with moderate to severe acne vulgaris. Research conducted in Makassar, South Sulawesi, as many as 13 samples that met the inclusion criteria. Clinical examination in patients with moderate acne vulgaris to severe and based on clinical manifestations, level of sebum measured before, and levels of estradiol. All patients given the autologous serum after being given doxycycline 200 mg single dose oral which will be applied every night. Furthermore monitored on day to 14 and day to 28. The data were processed using paired Wilcoxon test. Results improvement in clinical manifestations and levels of sebum on days 14 and 28 compared to day 1 was significantly (p <0.05). There were improvements in clinical manifestations and decrease sebum levels in patients with moderate to severe AV after application of autologous serum containing doxycycline.

Identification of Methicillin-Resistant Staphylococcus Epidermidis (MRSE) in Mild, Moderate and Severe Acne Patients

Acne cases caused by Staphylococcus epidermidis bacteria have been reported previously. This study identified methicillin resistant Staphylococcus epidermidis (MRSE) directly from pus speciment from acne patients at various degree of severity. There were 61% positive samples detected by Polymerase Chain Reaction (PCR) for MRSE using target gene mecA for PCR amplification of acne samples. Significant correlation between the severity of acne and its causative agent (MRSE) was not found.

The Relationship Between Serum Level of Interleukin-10 and State of the Disease with Atopic Dermatitis and Helminth in Children

Background: IL-10 is an antiinflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK cells, and macrophages. Regulatory cytokine interleukin-10 (IL-10) has been proposed as a key molecule involved in the attenuation of helminth infection and chronic inflammation, such as atopic dermatitis. The maintenance of the asymptomatic state is now recognized as reflecting an immunoregulatory environment, which may be promoted by parasites, and involves multiple levels of host regulatory cells and cytokines; currently, there is much interest in whether helminth-associated immune regulation may ameliorate allergy and autoimmunity. The objective of this study was to measure the IL-10 level in healthy person, atopic dermatitis, helminth infection and healthy persons. Methods: Levels of IL-10 was measured by ELISA technique. Kato-Katz method is used to determine the number of eggs of helminth. Results: Our study showed that those aged > 5 years old and helminth infection without atopic dermatitis had higher levels of IL-10 (3.05 ± 2.44) which was significantly higher (p 5 years old in others group. Also, no correlation between egg count of helminth and level of IL-10 in serum. Conclusion: The serum of IL-10 was significantly higher in children > 5 years with helminth infection without atopic dermatitis than children with atopic dermatitis.

Hair’s Zinc Level on Androgenic Alopecia

Androgenic alopecia is characterized by progressive loss of hair from the scalp. This research aimed to determine the hair and blood zinc levels in men with androgenic alopecia. The research was conducted in the Departement of Dermatovenereology of Dr. Wahidin Sudirohusodo Hospital, Makassar and the Center for Health Laboratory, Makassar, using the observational research method. The samples comprised 21 males with androgenic alopecia and 11 control samples without androgenic alopecia. The hair and blood of the samples were analyzed using the atomic absorption spectrophotometer receipts. The results showed that there was significant difference (p <0.05) between the levels of androgenic alopecia hair zinc and control. On blood zinc levels found no significant differences between androgenic alopecia and control. Hair zinc levels had a significant relationship with the degree of Hamilton, where the lower the levels of zinc in the hair androgenic alopecia, the greater the degree of Hamilton. However, things are different, between blood zinc levels in hair zinc levels and degrees of Hamilton that there is no significant difference. In this study also found between age and degree of Hamilton, where the increasing age, the greater the degree of Hamilton.