Fausta Ongaro

The Impact of Income and Employment Status on Leaving Home: Evidence from the Italian ECHP Sample

In this paper we investigate the role economic resources play in the decision of young Italian adults to leave the parental home. This is of particular interest given that, in Italy, young people leave home considerably later than in other European countries. We use the first two waves of the Italian sample of the European Community Household Panel. We use a Heckman selectiondtype probit procedure to account for left censoring and unobserved heterogeneity. We find that economic circumstances are important. In particular, we find personal income resources, as well as parental income levels, to be crucial in leaving home. Our results suggest that stable employment is an important prerequisite for men to start their own household. For women, on the other hand, finding a partner seems to the most important factor in becoming independent of their parents. Copyright Fondazione Giacomo Brodolini and Blackwell Publishers Ltd 2001.

Frailty, disability and survival in the elderly over the age of seventy: Evidence from "The Treviso Longeva (TRELONG) Study".

Frailty is a biological syndrome of decreased reserves and lower resistance to stressors, deriving from cumulative declines across multiple physiological systems and causing adverse outcomes. Physical frailty is easy to assess, strongly correlated to disability and to survival, considering the comorbidities, too. This working definition of frailty is inexpensive to apply, and provides a basis for standardized screening for risk of disability in older adults.

Physical activity, socialization and reading in the elderly over the age of seventy: what is the relation with cognitive decline? Evidence from "The Treviso Longeva (TRELONG) study".

Evidence in the literature suggests that physical activity, social contacts and cognitively stimulating activity, such as reading, often considered individually, may improve cognitive performance. Our work examines their interactions and confirms their positive effects on cognitive functions. The correlations between physical activity, socialization, reading and improved cognitive performance remained significant after adjusting for confounding factors, such as comorbidity and hearing function. Our work suggests that these factors are important for the prevention of cognitive decline in the elderly.

Body mass index, lifestyles, physical performance and cognitive decline: the "Treviso Longeva (TRELONG)" study.

ObjectivesThe relative contributions of risk factors, as body mass index (BMI), depression, chronic diseases, smoking, and lifestyles (as physical and performance activity, social contacts and reading habit) to cognitive decline in the elderly are unclear. We explored these variables in relation to 7-year cognitive decline in long-lived Italian elderly.DesignSecondary data analysis of a longitudinal study of a representative, age-stratified, population sample.SettingThe TREVISO LONGEVA (TRELONG) Study, in Treviso, Italy.Participants120 men and 189 women, age 77 years and older (mean age 80.2 ± 6.9 years) survivors after seven years of follow up.MeasurementsCognitive decline measured as difference between Mini-Mental State Examination (MMSE) score in 2003 and in 2010; Body mass index (BMI), handgrip, Short Physical Performance Battery (SPPB) score, social contacts, reading habit, sight, hearing, schooling, mediterranean diet and multiple clinical and survey data recorded at baseline in 2003.ResultsIn separate univariate analyses, age, SPPB score < 5, depressive symptoms (GDS) and more comorbidities (CCI) were associated with greater cognitive decline. Otherwise higher BMI, higher handgrip, reading habit, non-deteriorated sight and hearing, and schooling were protective. In a final multivariate model, age and higher BMI were associated with greater cognitive decline while reading habits was protective. SPPB score < 5 tends, though weakly, to be associated with greater cognitive decline. These associations remained with multivariate adjustment for gender, schooling, Charlson co-morbidity index (CCI) and baseline MMSE.ConclusionAge and higher baseline BMI, independent of gender, and other confounding factors, are risk factors for cognitive decline. Reading habit plays a protective role seven years later among northern Italian adults aged 70 years or older. Low physical performance tends, though weakly, to be associated with greater cognitive decline.

Introduction: Agent-Based Computational Demography

Originating from developments in computer science (also applied to natural sciences), a computational approach to the study of human behavior has developed that has gathered impetus in the literature during the 1990s. Agent-based computational models have become more and more used in the social sciences (i.e. in economics with the idea of Agent-based Computational Economics (ACE), and in sociology with the idea of Social Simulation). Different to the approach based on statistical analysis of behavioral data that aims to understand why specific rules are applied by humans, agent-based computational models presuppose (realistic) rules of behavior and try to challenge the validity of these rules by showing whether they can or cannot explain macroscopic regularities. In this introductory chapter, we argue that in order to study human populations, agent-based approaches are particularly useful from various theoretical perspectives. We urge demographers and other scholars interested in population studies to look at Agent-Based Computational Demography (ABCD) as a promising stream of research, which can improve our understanding of demographic behavior. We review and use the chapters of this book to substantiate our argumentations.

Factors related to disability: Evidence from the " Treviso Longeva (TRELONG) Study"

Prolongation of life is an important public health goal as long as there is an emphasis on the quality of life (QoL) and independent living. Diminishing abilities to ambulate and participate in activities of daily living point to a serious decline in functional health, increasing the risk of institutionalization and death. In our work we found a pattern of factors associated with disability, especially cognitive impairment, as well as stroke, physical activity and performance, reading, and the nutritional biomarkers, blood albumin and high-density lipoprotein cholesterol (HDL-C). The attention to this cluster of markers, suggesting multidimensional prevention, may have unexpected good effects against disability.

Body Mass Index, Cognition, Disability, APOE Genotype, and Mortality: The "Treviso Longeva" Study

OBJECTIVES The concurrent contributions of dynamic, interrelated late-life parameters, such as body mass index (BMI), cognition, and physical functioning on mortality in the elderly are unclear, as is the influence of APOE genotype. We explored these measures in relation to 7-year mortality in long-lived Italian elderly. DESIGN A representative, age-stratified, population sample. SETTING The Treviso Longeva (TRELONG) Study, in Treviso, Italy. PARTICIPANTS Three hundred eleven men and 357 women, aged 70 years and older (mean age 84 ± 8 years). MEASUREMENTS Seven-year mortality, BMI, Mini-Mental State Examination (MMSE) score, Activities of Daily Living (ADL), APOE genotype, and a variety of clinical and survey data. RESULTS In separate age- and sex-adjusted analyses, BMI <18.5 kg/m(2), MMSE ≤24, and ADL <6, were associated with greater 7-year mortality among adults aged 70 years and older. In a multivariate model including all factors, MMSE ≤24, and ADL <6 were associated with greater mortality; BMI ≥30 kg/m(2) was protective. There were no interactions between BMI, MMSE, or ADL. When excluding those dying within 3 years of baseline, only an MMSE ≤24 was related to mortality. APOEε4 was not related to mortality. CONCLUSION Higher MMSE score, higher ADL score, and higher BMI, independent of age, sex, and other factors, are markers for longer life among northern Italian adults aged 70 years or older. Global cognition, BMI, and physical functioning, assessed by short, simple tests are profound indicators of death within less than a decade.

Life satisfaction among older people in Italy in a gender approach

ABSTRACT Over the last few decades, increasing attention has been paid to the issue of wellbeing among older people, and life satisfaction has been used as an indicator to evaluate older peoples life conditions. This paper sheds some light on this topic with reference to Italy, a country characterised by an increasing ageing population. The aim is to examine life satisfaction among people aged 65 and older and its predictors. We adopt a gender approach to examine whether – as suggested by the literature – older men and women have different sources of satisfaction. We test this hypothesis in Italy, a country still characterised by an unbalanced public and private gender system. In doing this, we also control whether living arrangements – specifically living alone – influence the determinants of life satisfaction of older men and women. The data used are from the cross-sectional surveys ‘Aspects of Daily Life’, undertaken in Italy by the National Statistical Institute. The results do not show clear gender differences in the determinants of life satisfaction, with only some slight gender differences among those living alone. This suggests that the social and cultural environment may play a relevant role for older peoples life satisfaction.

Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva--TRELONG).

Insulin-like growth factor 1 (IGF-1) signaling modulation has been associated with increased lifespan in model organisms, while high levels of circulating interleukin-6 (IL-6) are a marker of disability and mortality. In the prospective, population-based “Treviso Longeva”− TRELONG Study from Italy (n = 668, age range 70–105.5 years at baseline, followed for seven years) we investigated the effects of survival on the IGF-1 receptor (IGF-1R) gene polymorphism rs2229765, the IL-6 gene promoter polymorphism rs1800795, and plasma concentrations of IGF-1 and IL-6, alone or in combination. We found a sex-dependent effect for the IGF-1R rs2229765 polymorphism, as male carriers of the homozygous A/A genotype survived longer, while the IL-6 rs1800795 genotype did not influence overall or sex-specific longevity. Higher IL-6 levels were more detrimental for survival among males than females, while IGF-1 had no dose–response effect. These findings sustain the hypothesis that sex-specific longevity relies on detectable differences in genetic and biochemical parameters between males and females.

Melatonin and the Charlson Comorbidity Index (CCI): The Treviso Longeva (Trelong) Study:

Introduction It has been reported that elderly subjects have a compromised ability to produce melatonin nightly, and that reduced melatonin levels may be a risk factor for cancer. The purpose of this study was to evaluate the relationship between melatonin levels and chronic diseases in a cohort of elderly subjects using the Charlson comorbidity index (CCI). Design We performed a secondary data analysis of a longitudinal study of a representative, age-stratified, sample population. Setting The Treviso Longeva (Trelong) study, in Treviso, Italy. Participants A total of 114 men and 146 women, aged 77 years and older, still alive after 7 years of follow-up. Measurements As an estimation of serum melatonin secretion levels, urinary 6-sulfatoxymelatonin (aMT6s) was assayed in the urine of 260 elderly subjects using an enzyme-linked immunosorbent assay (ELISA) kit (product 01-EK-M6S, ALPCO Immunoassays, Windham, NH). All aMT6s levels were creatinine standardized ([aMT6s]/[creatinine]), and the CCI was calculated. Results The melatonin levels decreased with aging despite not reaching statistical significance, and the decrease was more evident in males than in females (40.5 ng vs 47.0 ng aMT6s/mg creatinine, ns). Melatonin levels were significantly lower in patients reporting insomnia (p=0.05). The CCI score was inversely correlated with the levels of melatonin (p=0.03). Melatonin levels of subjects affected by CCI pathologies were significantly lower than those of healthy subjects (p=0.03) and of subjects suffering from diseases not included in the CCI and, therefore, less severe (p=0.03). Conclusion Melatonin appears to be a marker of disease state and severity, as well as of sleep disorders, in the elderly. These early findings would confirm the protective role of melatonin against several chronic diseases. The benefits of this agent as a possible medication should be more thoroughly clinically tested.