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Fionna Mitchell Martin

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Publication

Featured researches published by Fionna Mitchell Martin.

Bioorganic & Medicinal Chemistry Letters | 1999

The synthesis and biological evaluation of non-peptidic matrix metalloproteinase inhibitors

Fionna Mitchell Martin; R.Paul Beckett; Claire L. Bellamy; Paul F. Courtney; Stephen J. Davies; Alan Hastings Drummond; Rory Dodd; Lisa M. Pratt; Sanjay Ratilal Patel; Michelle L. Ricketts; Richard S. Todd; Andrew R. Tuffnell; John S. Ward; Mark Whittaker

Novel sulfonamide matrix metalloproteinase inhibitors of general formula (9) were synthesised by a route involving a stereoselective conjugate addition reaction. Enzyme selectivity was found to be dependant on the nature of the sulfonamide substituents. Compounds (9f, 9q) are potent selective collagenase inhibitors with good oral bioavailability.

Archive | 1995

SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS

Andrew N. Miller; Raymond Paul Beckett; Fionna Mitchell Martin; Mark Whittaker

Synlett | 1998

Use of the Ireland-Claisen Rearrangement in the Synthesis of 2,3-Disubstituted Succinates

Lisa M. Pratt; Stephen A. Bowles; Sally F. Courtney; Christopher Hidden; Christopher Norman Lewis; Fionna Mitchell Martin; Richard S. Todd

Archive | 1996

Preparation of allyl succinate derivatives and starting materials therefor

Fionna Mitchell Martin; Christopher Norman Lewis; Stephen A. Bowles; Richard S. Todd

Archive | 1995

N-(amino acid) substituted succinic acid amide derivatives as metalloproteinase inhibitors

Paul Beckett; Mark Whittaker; Andrew N. Miller; Fionna Mitchell Martin

Archive | 1996

Benzimidazole derivatives being dual histamine (h1) and platelet activating factor (paf) antagonists

Fionna Mitchell Martin; Christopher David Floyd; Zoe Marie Spavold; Mark Whittaker

Synlett | 2005

1,4-bis(arylsulfonyl)-1,2,3,4-tetrahydropyridines in synthesis : Stereoselective homo- and hetero-diels-alder reactions

Jean-Claude Adelbrecht; Donald Craig; Alice J. Fleming; Fionna Mitchell Martin

Archive | 1995

L-tert-leucine-2-pyridylamide

Raymond Paul Beckett; Fionna Mitchell Martin; Andrew N. Miller; Mark Whittaker

Archive | 1997

Metalloproteinase inhibitoren inhibitors metalloproteinase

Raymond Paul Beckett; Fionna Mitchell Martin; Andrew N. Miller; Richard S. Todd; Mark Whittaker

Archive | 1996

Inhibiteurs de metaloproteinases

Fionna Mitchell Martin; Christopher Norman Lewis; Mark Whittaker

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Collaboration

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Mark Whittaker

Hope College

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Andrew N. Miller

Illinois Natural History Survey

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Stephen A. Bowles

University of Bath

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Alan Hastings Drummond

University of London

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Donald Craig

Imperial College London

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Jean-Claude Adelbrecht

Imperial College London

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Mark Whittaker

Hope College

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R.Paul Beckett

University of Oxford

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Zoe Marie Spavold

University of Nottingham

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John S. Ward

Eli Lilly and Company

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