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Dive into the research topics where Francesca Astra Borruto is active.

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Featured researches published by Francesca Astra Borruto.


European Journal of Pediatric Surgery | 2012

Thoracoscopy versus thoracotomy for esophageal atresia and tracheoesophageal fistula repair: review of the literature and meta-analysis.

Francesca Astra Borruto; Pietro Impellizzeri; Angela Simona Montalto; Pietro Antonuccio; Emanuela Santacaterina; Gianfranco Scalfari; Francesco Arena; Carmelo Romeo

INTRODUCTION The thoracoscopic approach to esophageal atresia (EA) with tracheoesophageal fistula (TOF) represents a challenging procedure whose real benefits remains unclear. Our purpose is to identify, through a meta-analysis, clinical evidence of the reliability of the thoracoscopic repair (TR) for EA/TOF compared with the open repair. MATERIALS AND METHODS Defined PubMed search, with analysis of intraoperative and postoperative complications after open or thoracoscopic primary anastomosis for EA/TOF. RESULTS Five articles met the criteria of meta-analysis, being comparative studies between TR and conventional open repair (COR), although they were retrospective. One article was excluded because it was available only in Japanese. We observed a slight prevalence, statistically insignificant, of the intraoperative and postoperative complication rate for TR: odds ratio (OR) 1.29. Excluding the conversion rate, the meta-analysis between the complication rate for TR and COR did not show a significant difference (OR 0.64). Anastomosiss leaks and strictures considered together did not show a significant difference between the two techniques, p = not significant and OR of 0.56. Similar results were observed analyzing the single outcome of leaks and strictures; the meta-analysis did not show any significant differences with an OR, respectively, of 1.05 and 0.43. CONCLUSIONS The effectiveness of the endoscopic technique for EA/TOF repair is indicated with outcomes not different from open surgery. A randomized controlled trial is needed in this field to indicate which procedure is superior, open or TR.


Journal of Pediatric Surgery | 2010

Late hormonal function after testicular torsion

Carmelo Romeo; Pietro Impellizzeri; Teresa Arrigo; Pietro Antonuccio; Mariella Valenzise; Silvio Mirabelli; Francesca Astra Borruto; Gianfranco Scalfari; Francesco Arena; Filippo De Luca

INTRODUCTION Testicular torsion may be an important cause of male infertility. We aimed to investigate the late hormonal function in patients with testicular ischemia/reperfusion injury of the testis after orchidectomy or detorsion. METHODS Twenty patients (mean age, 13.6 years) were prospectively evaluated at a mean of 5 years after testicular torsion. The serum follicle-stimulating hormone, luteinizing hormone (before and after gonadotropin-releasing hormone stimulation), testosterone, and inhibin B were measured. Fifteen age-matched adolescents without evidence of endocrine disease were used as controls for inhibin B values. Data are quoted as mean +/- SEM. RESULTS Twelve patients were treated with detorsion and orchidopexy, and 8 underwent orchidectomy. Serum follicle-stimulating hormone, luteinizing hormone, and testosterone were all within the reference range. Inhibin B levels were significantly reduced in the 2 groups compared with the controls (34.5 +/- 5.2 vs 63.9 +/- 12.8 pg/mL, P = .02), but were not significantly different between the orchidectomy group and the group that underwent detorsion (41.3 +/- 9.7 vs 30.4 +/- 5.9 pg/mL, P = .41). CONCLUSION Hormonal testicular function can be compromised after testicular torsion, although the type of surgery (orchidectomy or orchidopexy) does not seem to change the effect of this ischemia/reperfusion injury.


Journal of Pediatric Surgery | 2010

Sclerotherapy for cervical cystic lymphatic malformations in children. Our experience with computed tomography-guided 98% sterile ethanol insertion and a review of the literature

Pietro Impellizzeri; Carmelo Romeo; Francesca Astra Borruto; Francesca Granata; Gianfranco Scalfari; Francesco Saverio De Ponte; Marcello Longo

PURPOSE The treatment of cystic lymphatic malformations of the neck and mediastinum is controversial. Surgical management may be limited by the invasiveness of the procedure, the complex anatomy of this region, and the high recurrence rate. An alternative therapeutic method is sclerotherapy. We report our experience in the treatment of cystic lymphatic malformations of the neck by computed tomography (CT)-guided instillation of 98% sterile ethanol in children. METHODS Eight children with clinical suspicion of cervical cystic lymphatic malformation were assessed by ultrasonography (US) and magnetic resonance imaging (MRI) to define the location, size, and number of cystic cavities. The CT-guided instillation of 98% sterile ethanol was performed. Cystic fluid was analyzed by fine-needle aspiration cytology. Clinical and US or MRI follow-up was performed after 1 and 3 months and at 1 and 2 years. RESULTS The results were excellent with complete disappearance of the lesion in 7 (87.5%) of 8 patients. One patient (12.5%) with satisfactory results required a second alcohol injection with an excellent outcome. No allergic reactions or complications were observed. CONCLUSIONS The CT-guided 98% sterile ethanol sclerotherapy is a good alternative to surgical therapy. This procedure seems accurate, minimally invasive, safe, low cost, and reliable without untoward complications. Moreover, it does not exclude later surgical treatment.


Journal of Pediatric Surgery | 2009

Accessory spleen torsion: rare cause of acute abdomen in children and review of literature

Pietro Impellizzeri; Angela Simona Montalto; Francesca Astra Borruto; Pietro Antonuccio; Gianfranco Scalfari; Francesco Arena; Carmelo Romeo

Torsion of an accessory spleen is an extremely rare condition. We describe an unusual case of acute abdomen caused by torsion of an accessory spleen in a 12-year-old boy. The patient underwent a laparotomy with splenectomy; the course was favorable. We discuss the clinical findings and values of preoperative instrumental diagnosis. The literature is also reviewed. This is the 11th case reported in the English literature. Torsion of an accessory spleen should be considered in the differential diagnosis of acute abdomen or subacute abdominal pain.


European Journal of Pediatric Surgery | 2013

Thoracoscopic treatment of congenital diaphragmatic eventration in children: lessons learned after 15 years of experience.

Francesca Astra Borruto; Cindy Gomes Ferreira; Christos Kaselas; Anne Schneider; Isabelle Lacreuse; I. Kauffmann; R. Moog; François Becmeur

INTRODUCTION We present our experience with the thoracoscopic treatment of congenital diaphragmatic eventration (CDE) in children through 15 years to evaluate the efficiency of the procedure and the potential risk of recurrence. Materials and METHODS We reviewed the medical files of patients treated for CDE through thoracoscopy from 2000 to 2011. Age at surgery, sex, side of the lesion, procedures details, postoperative course, and complications were analyzed. Mean follow-up was 12 months. RESULTS In this study, eight patients (five males and three females) aged from 6 months to 7 years underwent thoracoscopic plication for six right and two left eventrations; one conversion was necessary due to a too small operative field. Mean operative time was 60.5 minutes. A chest drainage was placed in six patients. We observed two recurrences from which the first one was treated thoracoscopically by endostapler resection/suturing and the other one by laparotomy. At follow-up, all patients were asymptomatic with a correct level of the diaphragm. CONCLUSIONS Thoracoscopic plication is feasible and safe, and we consider this approach as the gold standard for the treatment of CDE. However, we still need to carefully consider the possibility of introducing certain modifications to reduce the potential risk of recurrence.


Archive | 2013

Congenital Diaphragmatic Hernia

Francesco Molinaro; R. Angotti; Francesco Ferrara; Francesca Astra Borruto; M. Messina; François Becmeur

Congenital diaphragmatic hernia (CDH) is a defect of development of the pericardioperitoneal canals. In general, it occurs at 6–7 weeks of gestation. It is responsible for herniation of the abdominal organs into the thoracic cavity. CDH is delimited anteriorly by the diaphragm, sideways by the diaphragmatic pillars and posteriorly by the costal margin. CDH causes lung compression on the side of the diaphragmatic defect, precluding normal development of the lung (“lung hypoplasia”) [1, 2]. CDH has an incidence of 1 case per 3,000–5,000 in live births with a male predominance. CDH is not a hereditary disease. CDH is on the left side in 86% of cases (Figs 19.1 and 19.2).


European Journal of Pediatric Surgery Reports | 2013

Right bochdalek hernia associated with kartagener syndrome: developmental and clinical observations.

Carmelo Romeo; Nunzio Turiaco; Eloisa Gitto; Francesca Astra Borruto; Giuseppe Santoro

We present a novel case of the association of right-sided Bochdalek hernia, a diaphragmatic life-threatening malformation, and Kartagener syndrome, which is characterized by congenital bronchiectasis, chronic sinusitis, and situs inversus. The developmental and clinical findings are discussed. When an association of diaphragmatic hernia with situs viscerum inversus is encountered, physicians should be mindful of the possibility of Kartagener syndrome because this condition could significantly affect the morbidity of the patient.


Journal of Pediatric Surgery | 2012

Button cystostomy for bladder drainage: which children can benefit from this device?

Isabelle Lacreuse; R. Moog; Francesca Astra Borruto; François Becmeur; Cindy Gomes Ferreira; I. Kauffmann

AIM The aim of this study is to define which children could benefit from a button cystostomy. We describe a safe way to perform the insertion of a button cystostomy for urinary diversion and provide more precise instructions concerning the best indications for this device. MATERIALS AND METHODS We analyzed several criteria of the follow-up of all the patients who had a button cystostomy since 2007 including indications, age, urodynamic variables, and complications. RESULTS Twenty-one patients underwent a button cystostomy. A group of young children was included in the study (mean age, 2 years), in which most of the failed procedures were observed, whereas we had better results with the second group of older children (mean age, 12 years). CONCLUSIONS The analysis of indications and, more particularly, urodynamic variables regarding the quality of the results allows us to clearly define which children can benefit from this procedure with a good chance of success and low risk of complications.


Journal of Pediatric Surgery | 2010

Laparoscopic vs open varicocelectomy in children and adolescents: review of the recent literature and meta-analysis

Francesca Astra Borruto; Pietro Impellizzeri; Pietro Antonuccio; Alessandra Finocchiaro; Gianfranco Scalfari; Francesco Arena; Ciro Esposito; Carmelo Romeo


Pediatric Surgery International | 2009

Anterior urethral valves in children: an uncommon multipathogenic cause of obstructive uropathy

Salvatore Arena; Carmelo Romeo; Francesca Astra Borruto; Sergio Racchiusa; Vincenzo Di Benedetto; Francesco Arena

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Cindy Gomes Ferreira

Centre Hospitalier de Luxembourg

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