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Dive into the research topics where Franz Pirro is active.

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Featured researches published by Franz Pirro.


Bioorganic & Medicinal Chemistry Letters | 1998

Synthesis and antibacterial in vitro activity of novel analogues of nematophin

Thomas Himmler; Franz Pirro; Norbert Schmeer

The synthesis and in vitro antibacterial activity of new derivatives and analogues of nematophin are described. It was shown that the unsubstituted amide NH-group is essential for bioactivity. Alkyl- or arylsubstitution at the 1-position results in a distinct increase of antibacterial activity. Addition of protein (blood or serum) to the culture media reduces the inhibitory activity on bacteria.


Archive | 1997

Possibly substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives

Stefan Dr Bartel; Thomas Jaetsch; Thomas Himmler; Hans-Georg Rast; Werner Hallenbach; Ernst Heinen; Franz Pirro; Martin Scheer; Michael Stegemann; Hans-Peter Stupp; Heinz-Georg Wetzstein


Archive | 1999

Substituted 2-oxo-alkanoic acid-[2-(indol-3-yl)-ethyl] amides

Thomas Himmler; Franz Pirro


Archive | 2004

Novel use of quinolone antibiotics

Gert Daube; Markus Edingloh; Bernd Stephan; Franz Pirro; Agnès Limet


Archive | 2008

ß-Lactam-haltige Formulierungen mit erhöhter Stabilität in wässriger Lösung

Dirk Mertin; Bernd Bigalke; Franz Pirro


Archive | 1995

Pyrido[3,2,1-i,j][3,1]benzoxazine derivatives

Werner Hallenbach; Thomas Himmler; Thomas Jaetsch; Burkhard Mielke; Klaus Dieter Bremm; Rainer Endermann; Franz Pirro; Michael Stegemann; Heinz-Georg Wetzstein


Archive | 1997

Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate

Stefan Dr Bartel; Thomas Jaetsch; Thomas Himmler; Hans-Georg Rast; Werner Hallenbach; Ernst Heinen; Franz Pirro; Martin Scheer; Michael Stegemann; Hans-Peter Stupp; Heinz-Georg Wetzstein


Archive | 2008

Beta-LACTAM-CONTAINING FORMULATIONS WITH INCREASED STABILITY IN AQUEOUS SOLUTION

Dirk Mertin; Bernd Bigalke; Franz Pirro


Archive | 1995

1,9-bridged thiazolo[3,2-a]quinoline derivatives

Thomas Jaetsch; Werner Hallenbach; Thomas Himmler; Burkhard Mielke; Klaus Dieter Bremm; Rainer Endermann; Franz Pirro; Michael Stegemann; Heinz-Georg Wetzstein


Archive | 2008

COMPOSITIONS CONTENANT DU β-LACTAME À STABILITÉ ACCRUE DANS UNE SOLUTION AQUEUSE

Dirk Mertin; Bernd Bigalke; Franz Pirro

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