G. J. Miller

Antioxidant activity of phenols as related to effects of substituent groups

SummaryAntioxidant activity in lard was exhibited by all phenols which had electron-repelling groups in the 2 and 6 positions. No activity was shown by those which had electron-attracting groups in these positions.The mechanism of antioxidant action of alkyl phenols in lard does not appear to differ from that of di- or polyphenols. A free phenolic group was shown to be essential, and spectral absorption studies after autoxidation did not reveal any evidence for a dimer of the alkyl phenol. The dimer, stilbene quinone, reported isolated from oxidized petroleum oil, disappeared quite rapidly when added to oxidizing lard.

Histones and their modifications during amphibian metamorphosis

Abstract 1. 1. Histones from all developmental stages of Rana catesbeiana in the liver and erythrocytes were found to be qualitatively similar. 2. 2. Gas chromatographic analysis revealed a decrease in hydrolyzable acetate on the histones as metamorphosis progressed to the adult or on thyroxine treatment. 3. 3. Isotope incorporation revealed a decrease in liver histone acetylation and no change in erythrocyte histone acetylation during metamorphosis. 4. 4. It is suggested that large scale acetylation of histones is not required for gene activation during metamorphosis.

Some characteristics of kidney and liver lipids from the American antelope.

SummaryThe percentages of total lipids, phospholipids, and cholesterol in the kidney and liver of pregnant antelope are reported. The iodine values of the total lipids in these two organs are also listed. By the use of three collections of the antelope made about one month apart during the latter part of the gestation period, it was shown that there were no significant changes in the above lipid values during this period.