G Ni
University of Hong Kong
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Publication
Featured researches published by G Ni.
Journal of Biomechanics | 2007
Z Li; Cheng Yang; William W. Lu; Bing Xu; W.M. Lam; G Ni; Sunny Akogwu Abbah; F Yang; Kmc Cheung; Kdk Luk
The aim of the present study was to determine the influence of surface treatment on the mechanical properties of strontium-containing hydroxyapatite (Sr-HA) bioactive bone cement. Previously we developed an injectable bioactive cement (SrHAC) system composed of Sr-HA powders and bisphenol A diglycidylether dimethacrylate (Bis-GMA). In this study, the Sr-HA powder was subjected to surface treatment using acrylolpamidronate, a bisphosphonate derivative, which has a polymerizable group, to improve the interface between inorganic filler and organic matrix by binding Sr-HA and copolymerizing into the matrix. After surface treatment, the compression strength, bending strength, and stiffness of the resulting composites were defined by using a material testing machine (MTS) according to ISO 5833. The fracture surface of the bone cement specimen was observed with a scanning electron microscope. Invitro cytotoxicity of surface-treated SrHAC was also studied using a tetrazolium-based cell viability assay (MTS/pms) on human osteoblast-like cells, the SaOS-2 cell line. Cells were seeded at a density of 10(4)/mL and allowed to grow in an incubator for 48 h at 37 degrees C. Results indicated that after surface treatment, the compression strength and stiffness significantly improved by 22.68 and 14.51%, respectively. The bending strength and stiffness of the bioactive bone cement also showed 19.06 and 8.91% improvements via three-point bending test. The fracture surface micromorphology after compression and bending revealed that the bonding between the resin to surface-treated filler considerably improved. The cell viability indicated that the treated particles were nontoxic and did not inhibit cell growth. This study demonstrated a new surface chemistry route to enhance the covalent bonds between inorganic fillers and polymer matrix for improving the mechanical properties of bone cement. This method not only improves the overall mechanical performance but also increases osteoblastic activity.
Biomaterials | 2007
Z Li; W.M. Lam; Cheng Yang; Bing Xu; G Ni; Sunny Akogwu Abbah; Kung-Kai Cheung; Keith Dip-Kei Luk; William W. Lu
Biomaterials | 2006
G Ni; K.Y. Chiu; Ww Lu; Y. Wang; Y.G. Zhang; L.B. Hao; Z Li; W.M. Lam; S.B. Lu; Keith D. K. Luk
Biomaterials | 2006
G Ni; William W. Lu; Bing Xu; K.Y. Chiu; Cheng Yang; Z Li; W.M. Lam; Keith Dip-Kei Luk
Journal of Biomedical Materials Research Part B | 2006
G Ni; William W. Lu; K.Y. Chiu; Z Li; Daniel Tik-Pui Fong; Keith D. K. Luk
Biomaterials | 2006
G Ni; Y.S. Choy; Ww Lu; A.H.W. Ngan; K.Y. Chiu; Z Li; Ben Zhong Tang; Keith D. K. Luk
Journal of Biomedical Materials Research Part A | 2007
G Ni; Ww Lu; Ben Zhong Tang; Ahw Ngan; K. Y. Chiu; Kung-Kai Cheung; Z Li; Keith D. K. Luk
Journal of Orthopaedic Research | 2007
G Ni; W.W. Lu; Peter K. Y. Chiu; Youzhi Wang; Z Li; Ye Zhang; Bing Xu; L.F. Deng; Keith D. K. Luk
Journal of Biomedical Materials Research Part B | 2007
Z Li; Cheng Yang; William W. Lu; Bing Xu; W.M. Lam; G Ni; Sunny Akogwu Abbah; F Yang; Kenneth M.C. Cheung; Keith Dip-Kei Luk
Archive | 2010
G Ni; Jh Lin; Pky Chiu; Z Li; Ww Lu