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G. Wille

Leiden University

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Featured researches published by G. Wille.

Tetrahedron Letters | 1981

A new approach to the synthesis of phosphotriester intermediates of nucleosides and nucleic acids

G.A. van der Marel; C. A. A. Van Boeckel; G. Wille; J. H. Van Boom

Abstract Aryl phosphorodichloridates can be converted by means of 1-hydroxybenzotriazole into an effective phosphorylating agent, which can be applied to the synthesis of phosphotriester intermediates of nucleic acids.

Nucleic Acids Research | 1977

Synthesis of oligonucleotides with sequences identical with or analogous to the 3′ - end of I6S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method1

J. H. Van Boom; P. M. J. Burgers; G.A. van der Marel; C. H. M. Verdegaal; G. Wille

Nucleic Acids Research | 1982

A general method for the synthesis of 5'-monophosphates of DNA fragments via phosphotriester intermediates

G.A. van der Marel; C. A. A. Van Boeckel; G. Wille; J. H. Van Boom

Nucleic Acids Research | 1983

Proton NMR studies on the covalently linked RNA-DNA hybrid r(GCG)d(TATACGC). Assignment of proton resonances by application of the nuclear Overhauser effect

Jan-Remt Mellema; C. A. G. Haasnoot; G.A. van der Marel; G. Wille; C. A. A. Van Boeckel; J. H. Van Boom; C. Altona

Recueil des Travaux Chimiques des Pays-Bas | 2010

Synthesis of oligoribonucleotides with sequences identical to the nucleation region of Tobacco Mosaic Virus RNA: Preparation of AAG, AAGAAG and AAGAAGUUG via phosphotriester methods†

J. A. J. Den Hartog; G. Wille; J. H. Van Boom

Recueil des Travaux Chimiques des Pays-Bas | 2010

Conformational analysis of an RNA triplet in aqueous solution: m62A-U-m62A studied by two-dimensional nuclear magnetic resonance at 500 MHz†

Peter P. Lankhorst; Cornelis M. Groeneveld; G. Wille; Jacques H. van Boom; Cornelis Altona; C. A. G. Haasnoot

Nucleic Acids Research | 1983

Conformational analysis of a ribopentandeolde tetraphosphate in aqueous solution. A two-dimensional NMR study at 500 MHZ1

Peter P. Lankhorst; G. Wille; Jacques H. van Boom; Conelis Altona; Comdis A.G. Haasnoot

Recueil des Travaux Chimiques des Pays-Bas | 2010

Phosphotriester synthesis of DNA fragments on cellulose and polystyrene solid supports

G.A. van der Marel; J. E. Marugg; E. de Vroom; G. Wille; M. Tromp; C. A. A. Van Boeckel; J. H. Van Boom

Biochemistry | 1982

Chemical synthesis of a messenger ribonucleic acid fragment: AUGUUCUUCUUCUUCUUC.

Jack A. J. Den Hartog; G. Wille; Rolf A. Scheublin; Jacques H. van Boom

Nucleic Acids Research | 1977

Synthesis of oltgonucleotides with sequences identical with or analogous to the 3′-end of 16S ribosomal RNA of Es cherichia coli: preparation of m62A-C-C-U-C-C and A-C-C-U-C-m42C via phosphotriester intermediates1

J. H. Van Boom; P. M. J. Burgers; Roberto Crea; G.A. van der Marel; G. Wille

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J. H. Van Boom

Leiden University

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G.A. van der Marel

Leiden University

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C. A. A. Van Boeckel

Organon International

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C. Altona

Leiden University

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Jan-Remt Mellema

Organon International

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H. Westerink

Leiden University

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Jacques H. van Boom

Leiden University

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Peter P. Lankhorst

Leiden University

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C. A. G. Haasnoot

Radboud University Nijmegen

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P. M. J. Burgers

Leiden University

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