Gabriela Salatino Liedke

Influence of Voxel Size in the Diagnostic Ability of Cone Beam Tomography to Evaluate Simulated External Root Resorption

This study assessed in vitro the diagnostic ability of cone beam computed tomography (CBCT) scans with different voxel resolutions in the detection of simulated external root resorption (ERR). For that purpose, 59 teeth were viewed through iCAT tomography (Imaging Sciences International, Inc, Hatfield, PA) following three protocols in which the variation was the voxel resolution (0.4, 0.3, and 0.2mm). A calibrated examiner blinded to the protocol assessed the images through the i-CAT View software (Imaging Sciences International, Inc). The chi-square statistical analysis did not show associations between voxel resolution, section plane, size of cavity, and radicular third. Sensitivity and specificity values were similar. However, likelihood ratio values of 6.4 for a 0.4-mm voxel, 16 for a 0.3-mm voxel, and 12 for a 0.2-mm voxel were found. It was concluded that CBCT is a reliable method for the investigation of simulated ERR, and a 0.3-mm voxel appeared to be the best protocol, associating good diagnostic performance with lower X-ray exposure.

Detection of vertical root fractures by conventional radiographic examination and cone beam computed tomography – an in vitro analysis

OBJECTIVES  This study compared the ability of conventional radiographic and cone beam computed tomography (CBCT) examinations to detect vertical root fractures (VRF) in teeth with or without root canal treatment and metallic posts. Furthermore, the influence of using different voxel sizes from CBCT images was assessed. METHODOLOGY  Sixty single-rooted human teeth were randomly divided into two groups: experimental and control. Twenty teeth were endodontically prepared and obturated with gutta-percha, twenty had a metallic postcemented after the filling, and twenty had no preparation. The teeth from the experimental group were fractured. All teeth were radiographed with three different horizontal angles, and after, CBCT images were acquired following three protocols in which the variation was the voxel resolution (0.4, 0.3, and 0.2 mm). Three calibrated examiners assessed the images. RESULTS  Chi-squared test showed no statistical difference among the images in detecting VRFs. The results of the diagnostic performance tests presented similar ability to detect VRFs when conventional radiographic examination was compared with 0.2 and 0.3-voxel CBCTs scans, in roots without endodontic treatment and metallic post. Moreover, specificity, sensitivity, and accuracy findings were similar for both 0.2 and 0.3-voxel resolution scans for teeth that are not root filled. However, it was observed that in teeth with root canal treatment and a post, the accuracy was higher when 0.2-mm voxel resolution was used. CONCLUSION  The radiographic examination with horizontal angle variation should be encouraged as the first complementary approach to assess the presence of VRFs. If conventional imaging is not capable to provide adequate information, CBCT can be indicated if a root fracture is strongly suspected. The root condition should then guide the voxel resolution choice, selecting 0.3-voxel for not root filled teeth and 0.2-voxel for teeth with filling and/or a post.

A comparative study of lateral cephalograms and cone-beam computed tomographic images in upper airway assessment

The purpose of this study was to evaluate the accuracy of airway measurements from lateral cephalograms, cone-beam computed tomographic (CBCT) lateral reconstructions, and CBCT axial planes, as well as to correlate these findings with area measurements acquired with the latter imaging method. Landmarks were defined for the measurements of naso- and oropharynx of 30 patients (12 males and 18 females, mean age 17.5 years), for different planes, using linear antero-posterior measurements and the corresponding area. Analysis of variance showed significant differences in the linear measurements of the oropharynx between the two methods, although all measurements assessed corresponded to the respective areas. The linear measurements of the airway space obtained using the different techniques correlated positively with the respective area measurements, which demonstrate the reliability of the investigated techniques.

Influence of a programme of professional calibration in the variability of landmark identification using cone beam computed tomography-synthesized and conventional radiographic cephalograms

OBJECTIVES The validity of any measurement obtained through a cephalogram largely depends on the reproducibility of the cephalometric landmarks. The purpose of this study is to evaluate the influence of a programme of professional calibration (PPC) on the variability of landmark identification comparing conventional radiographs and cone beam CT (CBCT)-synthesized cephalograms. METHODS 5 graduate students in oral radiology identified 20 cephalometric landmarks from cephalograms generated from conventional radiographs (RADs), Ray-Sum CBCT-synthesized cephalograms (CBTs) and half-skull CBT (HSTs) from 10 patients. After a period of reinforcement on instruction and calibration with inter- and intraexaminer assessment of reproducibility (intraclass coefficient correlation scores > 0.75) for RADs, CBTs and HSTs obtained from 5 different patients, observers were asked to repeat the analysis of the first 10 patients under the same circumstances. Values in millimetres represented each landmark in a table of Cartesian co-ordinates (x- and y-axes). RESULTS ANOVA showed significant reduction in variability levels after the PPC, and there were no differences among the methods of image acquisition. Repeated measures ANOVA indicated that the PPC accounted for reduction in variability levels in 14 of 20 landmarks. CONCLUSIONS The results suggest that a PPC has more influence than the type of image acquisition on variability of landmark identification based on two-dimensional cephalometric analysis. Cephalograms obtained from RAD or CBCT can be considered equivalent for clinical and experimental applications.

Comparative study between conventional and cone beam CT-synthesized half and total skull cephalograms

OBJECTIVES The aim of this study was to compare cephalometric measurements obtained from conventional cephalograms with total and half-skull synthesized cone beam CT (CBCT) cephalograms. METHODS Cephalometric analyses of 30 clinically symmetric patients were conducted by a calibrated examiner on conventional and CBCT-synthesized cephalograms (total, right and left). Reproducibility was investigated using the intraclass correlation coefficient (ICC). The Bland-Altman analysis was used to assess the agreement of the measurements from each factor obtained by conventional, total, right and left CBCT-synthesized cephalograms. RESULTS The ICC was above 0.9 for most of the 40 cephalometric factors analysed, revealing similar levels of reproducibility. When the measurements obtained from conventional and CBCT-synthesized cephalograms were compared, the Bland-Altman analysis showed a strong agreement between them. CONCLUSIONS Half-skull CBCT-synthesized cephalograms offer the same diagnostic performance and equivalent reproducibility in terms of cephalometric analysis as observed in conventional and total CBCT-synthesized cephalograms.

Comparison between two tomographic sections in the diagnosis of external root resorption

Objectives To assess the accuracy of coronal and sagittal CT sections to detect cavities simulating root resorption. Material and Methods 60 mandibular incisors were embedded in plaster bases, and cavities with 0.6, 1.2 or 1.8 mm in diameter and 0.3, 0.6 or 0.9 mm in depth (small, medium and large cavities) were drilled on the buccal surfaces with high-speed round burs with diameters of 0.6, 1.2 and 1.8 mm to simulate external inflammatory root resorption. Simulations in the cervical, middle and apical thirds of each tooth root were made randomly. The Dental Scan software was used to obtain 1-mm-thick axial images from direct scanning, which were reconstructed in the coronal and sagittal planes using 3D software (Syngo FastView). Each series was loaded into the software. Fourteen images of each tooth were reconstructed in the coronal plane and 14 in the sagittal plane. A total of 1,652 images were obtained for analysis. Series information, tooth number and the plane reconstructed were stored. The images generated were saved on a CD-ROM together with the visualization software (Syngo FastView). Images were analyzed by a previously calibrated blinded, radiologist. Cochran’s Q test was conducted separately for each region analyzed followed by pair-wise comparison by the McNemar test (p=0.05). Results No statistically significant difference (p>0.05) was observed in the diagnosis of simulated resorption between the apical, middle, and coronal thirds. When the axial plane was assessed separately, diagnoses were statistically different (p<0.05) among the three root thirds. The apical third differed significantly (p<0.05) from the cervical and middle thirds. Diagnostic errors were more often observed in the apical third compared to the cervical and middle thirds. Mid-sized cavities revealed no statistically significant differences (p>0.05) between planes, irrespective of the third in which the resorptions were located. Conclusion When tomographic sections are requested for the diagnosis of buccal or lingual external root resorption, sagittal sections afford the best image characterization of the resorption process.

Radiographic diagnosis of dental restoration misfit: a systematic review

The objective of this study was to perform a systematic review on the use of radiographic methods for the diagnosis of misfit in dental prostheses and restorations. The MEDLINE bibliographic database was searched from 1950 to February 2014 for reports on the radiographic diagnosis of misfits. The search strategy was limited to English-language publications using the following combined MeSH terms in the search strategy: (Dental Restoration OR Dental Prosthesis OR Crown OR Inlays OR Dental Abutments) and (Dental Leakage OR Prosthesis Fitting OR Dental Marginal Adaptation OR Surface Properties) and (Radiography, Dental OR Radiography, Dental, Digital OR Cone-Beam Computed Tomography). Twenty-eight publications were identified and read in full text, and 14 studies fulfilled criteria for inclusion. Information regarding the use of radiographic methods for the diagnosis of misfits in dental prosthesis and restorations, and in which the methodology/results comprised information regarding how the sample was collected/prepared, the method, imaging protocol, presence of a reference test and the outcomes were evaluated. QUADAS criteria was used to rate the studies in high, moderate or low quality. The evidence supporting the use of radiographic methods for the diagnosis of misfits in dental prosthesis and restorations is limited to low-/moderate-quality studies. The well-established intra-oral orthogonal projection is still under investigation and considered the most appropriate method, both when evaluating the relation between dental restoration to tooth and abutment to implant. Studies using digital radiographs have not evaluated the effect of image post-processing, and tomography has not been evaluated.

Imaging evaluating of the implant/bone interface—an in vitro radiographic study

OBJECTIVES To analyze the diagnostic accuracy of conventional and digital radiographic images and the impact of digital filters in evaluating the bone-implant interface. METHODS Titanium implants were inserted into 74 fresh bovine ribs blocks, 37 fitting tight to the bone walls (simulating the existence of osseointegration) and 37 with a gap of 0.125 mm (simulating a failure in the osseointegration process). Periapical radiographs were taken with conventional film and two phosphor plate systems [VistaScan® (Dürr Dental, Bietigheim-Bissingen, Germany) and Express® (Instrumentarium, Tuusula, Finland)]. Digital radiographs were investigated with and without enhancement filters. Three blinded examiners assessed the images for the presence of juxtaposition in the bone-implant interface using a five-point Likert scale. Sensitivity, specificity and the area under the receiver-operating characteristic curve (AUC) and its 95% confidence interval (CI) were calculated for each variable. Intraexaminer and interexaminer agreements were analyzed using Kendalls concordance test. RESULTS Intraexaminer and interexaminer agreements were >0.80 for both digital and conventional images. Conventional radiographs (AUC = 0.963/CI = 0.891 to 0.993) and digital images with high enhancement filters such as Caries2 (AUC = 0.964/CI = 0.892 to 0.993), Endo (AUC = 0.952/CI = 0.875 to 0.988) and Sharpen3 (AUC = 0.894/CI = 0.801 to 0.954) showed the greatest accuracy for evaluating the bone-implant interface. Original images from both digital systems and the further enhancement filters tested showed low sensitivity for the diagnosis task tested. CONCLUSIONS Conventional radiographs or digital radiographs with high-pass filters could help enhance diagnosis on implant-bone interface.

Accuracy of detecting and measuring buccal bone thickness adjacent to titanium dental implants—a cone beam computed tomography in vitro study

OBJECTIVES The aim of this study was to assess the accuracy of detecting and measuring buccal bone thickness (BBT) adjacent to titanium implants in cone beam computed tomography (CBCT) images. STUDY DESIGN Titanium implants (1, 2, or 3), abutments, and metal-ceramic crowns were inserted into 40 bone blocks with various BBTs. CBCT images were acquired in various settings: Voxel sizes (0.2 and 0.13 mm) and reconstruction section thicknesses (2.0 and 5.0 mm) were assessed by 3 examiners. True BBT was measured in digital photographs of the bone blocks. Buccal bone detection was evaluated by sensitivity and specificity. BBT was evaluated by 1-way analysis of variance (ANOVA) between the true and the CBCT measurements and by calculating the difference between the true measurement and the CBCT measurement (Di-BBT). RESULTS Detection of buccal bone exhibited high sensitivity (0.86-1) and low specificity (0.14-1). More implants in the field of view, large voxel size, and thick image reconstruction sections had a negative impact on buccal bone detection. ANOVA showed statistically significantly larger BBT for the CBCT measurements in all settings (1.07-1.21 mm) compared with the true measurements (0.85 mm). Di-BBT was mostly within 0.5 mm. CONCLUSIONS BBT adjacent to titanium implants is overestimated when evaluated on CBCT cross-sectional images.

Imaging Factors Impacting on Accuracy and Radiation Dose in 3D Printing

ObjectivesTo compare reconstructed area and surface roughness of 3D models acquired using nine image acquisition protocols. Radiation dose was also compared among acquisition protocols.MethodsA dry craniofacial specimen was scanned using three CT devices (a cone beam CT, a 16-channel fan beam CT, and a 64-channel fan beam CT), with three different acquisition protocols each. Nine 3D models were manufactured using polylactic acid. Surface roughness and reconstructed area were determined for each 3D model. The radiation dose during acquisitions was measured using lithium crystals. ANOVA was used to compare the data among the 3D models. Linear function optimization techniques based on stochastic variables were applied to identify the most suitable protocol for use.ResultsFor surface roughness, statistically significant differences were observed among all 3D models and the specimen. For reconstructed area, CBCT and one CT-16 channel protocols originated 3D models statistically significant different from the specimen. Higher radiation doses were observed with fan beam CT acquisitions.ConclusionsAll three CT devices were suitable for 3D printing when used at full resolution. The highest reconstruct area vs. radiation dose ratio was found for 64-channel CT devices.