Gamze Akbulut

Metabolic syndrome (MS) in elderly: A cross sectional survey

This study was conducted to determine the prevalence of metabolic syndrome (MS) in Turkish elderly. All data were collected in a cross-sectional based survey on 266 elderly aged above 65 years living in capital city of Turkey, Ankara. MS was defined according to National Cholesterol Education Program: Adult Treatment Panel III (NCEP ATP III) criteria. In the total sample of participants, the 61.7% (n=164) of the group has been diagnosed as MS. High blood pressure (BP) and waist circumference (WC) and low high density lipoprotein cholesterol (HDL-C) were the criteria of MS with highest prevalence in both gender. In addition female participants have higher systolic blood pressure (93.4%) and WC (79.1%) and lower HDL-C (69.2%) than the men (74.4%, 31.1% and 52.2% respectively). Weight correlated significantly with triglyceride (TG) and MS (p<0.001). WC was the anthropometric variable which had the highest correlation with the MS (r=0.338, p<0.001). Our study indicates that MS is highly prevalent in the elderly people particularly among women. Our findings may be helpful in formulating public health policies and prevention strategies focus on elderly population.

Relationship between dietary mineral intake and blood pressure (BP) in the elderly in Turkey

The aim of this study was to determine the relationship between daily dietary mineral (Na, K, Ca and Mg) intake and BP in the elderly. This study was conducted on 390 elderly volunteers (≥ 65 years). Subjects were randomly selected from the general population of Ankara, Turkey. Anthropometric measurements, lipid profiles, and mean systolic and diastolic BP (SBP and DBP) of all the participants were measured. To determine the mineral intake of the participants, food consumption was measured with a 24-h dietary recall. The 49.3% of participants were found to be hypertensive, 25.1% to be pre-hypertensive and 25.6% were normotensive according to the JNC-7 Guidelines, except for daily Mg and Na intake, the energy, macronutrient and micronutrient intake of groups were not significantly different (p>0.05). A significant inverse correlation between daily Ca intake and SBP was found in the pre-hypertensive group when age and gender adjusted regression analyses were performed (B=-0.006, p<0.05). Na intake and Na/K ratio were directly associated with SBP in the hypertensive group. In conclusion, SBP was found to be most related to dietary Na and Ca intake, and Na-to-K ratio in the elderly population.

Plasma orexin‑A and ghrelin levels in patients with chronic obstructive pulmonary disease: Interaction with nutritional status and body composition

Orexin-A and ghrelin are two important polypeptides that stimulate food intake, however, there is a lack of sufficient information concerning their plasma levels in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the association between plasma orexin-A and ghrelin levels with food consumption and body composition in patients with stable phase COPD. In total, 40 patients (age, 44–80 years; male, 31; female 9) who were in the stable phase of COPD were included in the study. Blood samples for plasma orexin-A and ghrelin analysis were collected after 8–12 h of fasting; certain anthropometric measurements were obtained and a 24-h dietary recall was recorded. The mean plasma orexin-A levels in the male and female patients were 1.3±0.37 and 1.4±0.13 ng/ml, respectively, while the mean plasma ghrelin levels were 25.9±7.31 and 27.3±8.54 ng/ml, respectively. No significant correlation was observed between the body mass index and plasma orexin-A and ghrelin levels or between the plasma ghrelin levels and dietary nutrient intake (P>0.05). The plasma orexin-A levels were demonstrated to be higher in patients with a higher dietary total fibre intake (r=0.303, P=0.022). A similar correlation was observed between plasma orexin-A levels and dietary intake of soluble (r=0.033, P=0.029) and insoluble (r=0.335, P=0.024) fibre, as well as between the daily consumption of calcium and the levels of plasma orexin-A (r=0.065, P=0.046). Therefore, the results of the present study indicated that a positive correlation existed between dietary nutrient intake and plasma orexin-A levels in patients with COPD.

Daily Dietary Energy and Macronutrient Intake and Anthropometric Measurements of the Peritoneal Dialysis Patients

Introduction: This study was planned to investigate the relation between dietary macronutrient status and anthropometric measurements in peritoneal dialysis (PD) patients. Materials and methods: A total of 28 clinically stable patients were enrolled in this study. All patients were taken a dietary therapy according to the guidelines of the American Journal of Kidney Foundation for 12 weeks. The anthropometric measurements were taken by bioelectrical impedance analyzer. The daily macronutrient intakes of the patients were calculated by the food consumption records. Results: The mean age was 48.3 ± 13.10 years [56.3 ± 7.41 years for males (n = 14) and 40.3 ± 12.84 years for females (n = 14)]. There were significant changes in fat percentage (%), total body water (TBW; %, L), extracellular water (ECW; %, L), basal metabolic rate over body weight (BMR/BW), and body fat mass index (BMFI) in males (p < 0.05), but there was no change in females (p > 0.05). The daily dietary energy and protein intakes were under the recommended level in the study period. Conclusion: Patients undergoing PD frequently have low intakes of protein and energy. It is recommended that individuals undergoing PD periodically maintain 3-day dietary records followed by dietary interviews conducted by a dietitian.

Comparison of energy balance-related behaviours and measures of body composition between Turkish adolescents in Turkey and Turkish immigrant adolescents in the Netherlands

OBJECTIVE To explore the influences of migration to a Western country on obesity and related risk factors by comparing measures of body composition and energy balance-related behaviours between Turkish adolescents in Turkey (TR-TR) and adolescents from Turkish immigrant ethnicity in the Netherlands (TR-NL). DESIGN Cross-sectional survey or baseline intervention data from six Dutch school-based studies and one Turkish study. SETTING Primary and secondary schools. SUBJECTS A total of 915 (49 % girls; mean age 13·1 (sd 0·8) years) TR-TR adolescents and 433 (51 % girls; mean age 11·7 (sd 1·3) years) TR-NL adolescents were included. Outcome measures were self-reported sugar-containing beverage consumption, fruit and vegetable intake, screen time, physical activity, measured body height and weight, BMI, waist and hip circumferences, and skinfold thicknesses. RESULTS Our data showed that more TR-NL adolescents were overweight (31 % v. 26 %) and obese (9 % v. 6 %) and had significantly higher mean BMI (21·1 v. 20·0 kg/m2), waist circumference (72·2 v. 71·3 cm) and suprailiac skinfold thickness (19·8 v. 13·1 mm) than TR-TR adolescents. TR-NL adolescents reported significantly higher sugar-containing beverage consumption (1173 v. 115 ml/d), less fruit and vegetable intake (295 v. 647 g/d), less screen time (253 v. 467 min/d) and higher physical activity levels (61 v. 27 min/d) than TR-TR adolescents. CONCLUSIONS Immigrant adolescents in the Netherlands were more often overweight and had a less favourable dietary pattern than their peers in Turkey, while their physical activity and screen time patterns were more favourable. These results suggest that adolescents from Turkish immigrant ethnicity in the Netherlands have adopted lifestyles towards the host culture.

Two Current Hormones Related to Obesity : Nesfatin-1 and Omentin-1

leri, besin alımını tetikleyen “açlık” hissi veya yeterli enerji alımı sağlandığında besin alımını inhibe eden “tokluk” hissini ortaya çıkaran regülatörler bir denge içindedir. Bu sistemde oluşan bir dengesizlik, obezite patogenezinde etkili faktörlerden birisidir.1 Gastrointestinal sistemden türeyen ve besin alımını inhibe eden birçok peptid bulunmaktadır. Yeni keşfedilen ve anoreksijenik peptitlerden biri olarak tanımlanan “Nesfatin-1”,

Prevalence of metabolic syndrome using NCEP-ATPIII and ınternational dietetics federation (IDF) definitions: A cross- sectional study in Turkish adults

To estimate the prevalence of metabolic syndrome using international dietetics federation (IDF) versus National cholesterol education program; adult treatment panel III (NCEP-ATPIII) definitions in Turkish adults. A cross-sectional study was conducted on a total of 1531 (male 758 and female 773) Turkish adults, aged between 20 to 64 years. Subjects were randomly selected from the general population of Ankara. The overall prevalence of MetS, as defined by NCEP-ATPIII and IDF was 48.2 and 56.4%, respectively. The agreement between National cholesterol education program (NCEP) and IDF definitions was substantial (kappa: 0.79). The prevalence was increased significantly according to increasing age in women, but was not different by age group in men. The prevalence of MetS in all age groups was higher in women. Hypertriglyceridemia and low High-density lipoprotein cholesterol (HDLC) were the criteria of metabolic syndrome (MetS) with the highest prevalence. According to IDF criteria, the frequency of participants with high fasting plasma glucose (FPG) and Waist circumference (WC) was higher than the participants with adult treatment panel III (ATP III) criteria. The prevalence of the MetS was found to be very high, especially in women. The IDF definition resulted in a higher prevalence of metabolic syndrome than the NCEP-ATPIII in the entire Turkish population. The agreement between the IDF and NCEP definitions for metabolic syndrome was very good. Key words: Metabolic syndrome, NCEP-ATPIII, IDF, adult.