Hilal Yildiran

Metabolic syndrome (MS) in elderly: A cross sectional survey

This study was conducted to determine the prevalence of metabolic syndrome (MS) in Turkish elderly. All data were collected in a cross-sectional based survey on 266 elderly aged above 65 years living in capital city of Turkey, Ankara. MS was defined according to National Cholesterol Education Program: Adult Treatment Panel III (NCEP ATP III) criteria. In the total sample of participants, the 61.7% (n=164) of the group has been diagnosed as MS. High blood pressure (BP) and waist circumference (WC) and low high density lipoprotein cholesterol (HDL-C) were the criteria of MS with highest prevalence in both gender. In addition female participants have higher systolic blood pressure (93.4%) and WC (79.1%) and lower HDL-C (69.2%) than the men (74.4%, 31.1% and 52.2% respectively). Weight correlated significantly with triglyceride (TG) and MS (p<0.001). WC was the anthropometric variable which had the highest correlation with the MS (r=0.338, p<0.001). Our study indicates that MS is highly prevalent in the elderly people particularly among women. Our findings may be helpful in formulating public health policies and prevention strategies focus on elderly population.

Relationship between dietary mineral intake and blood pressure (BP) in the elderly in Turkey

The aim of this study was to determine the relationship between daily dietary mineral (Na, K, Ca and Mg) intake and BP in the elderly. This study was conducted on 390 elderly volunteers (≥ 65 years). Subjects were randomly selected from the general population of Ankara, Turkey. Anthropometric measurements, lipid profiles, and mean systolic and diastolic BP (SBP and DBP) of all the participants were measured. To determine the mineral intake of the participants, food consumption was measured with a 24-h dietary recall. The 49.3% of participants were found to be hypertensive, 25.1% to be pre-hypertensive and 25.6% were normotensive according to the JNC-7 Guidelines, except for daily Mg and Na intake, the energy, macronutrient and micronutrient intake of groups were not significantly different (p>0.05). A significant inverse correlation between daily Ca intake and SBP was found in the pre-hypertensive group when age and gender adjusted regression analyses were performed (B=-0.006, p<0.05). Na intake and Na/K ratio were directly associated with SBP in the hypertensive group. In conclusion, SBP was found to be most related to dietary Na and Ca intake, and Na-to-K ratio in the elderly population.

Plasma orexin‑A and ghrelin levels in patients with chronic obstructive pulmonary disease: Interaction with nutritional status and body composition

Orexin-A and ghrelin are two important polypeptides that stimulate food intake, however, there is a lack of sufficient information concerning their plasma levels in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to investigate the association between plasma orexin-A and ghrelin levels with food consumption and body composition in patients with stable phase COPD. In total, 40 patients (age, 44–80 years; male, 31; female 9) who were in the stable phase of COPD were included in the study. Blood samples for plasma orexin-A and ghrelin analysis were collected after 8–12 h of fasting; certain anthropometric measurements were obtained and a 24-h dietary recall was recorded. The mean plasma orexin-A levels in the male and female patients were 1.3±0.37 and 1.4±0.13 ng/ml, respectively, while the mean plasma ghrelin levels were 25.9±7.31 and 27.3±8.54 ng/ml, respectively. No significant correlation was observed between the body mass index and plasma orexin-A and ghrelin levels or between the plasma ghrelin levels and dietary nutrient intake (P>0.05). The plasma orexin-A levels were demonstrated to be higher in patients with a higher dietary total fibre intake (r=0.303, P=0.022). A similar correlation was observed between plasma orexin-A levels and dietary intake of soluble (r=0.033, P=0.029) and insoluble (r=0.335, P=0.024) fibre, as well as between the daily consumption of calcium and the levels of plasma orexin-A (r=0.065, P=0.046). Therefore, the results of the present study indicated that a positive correlation existed between dietary nutrient intake and plasma orexin-A levels in patients with COPD.

Serum Antioxidant Vitamin Levels in Patients with Coronary Heart Disease

The aim of this study was to investigate anthropometric measurements, body composition, and serum antioxidant vitamin levels in men with coronary heart disease (CHD). Thirty-five men with CHD and 31 men without CHD, aged 40 - 65 years, were included this study. Dietary records and anthropometric measurements of each participant were recorded by researchers and serum antioxidant vitamin levels and lipid profiles were analyzed. Fat mass (FM) and the percentage of fat mass (FM%) in men with CHD was higher than in men without CHD (p < 0.05). Lipid profiles were found to be similar in both groups, with the exception of high-density lipoprotein cholesterol (HDL-C). Men with CHD had lower HDL-C levels than men without CHD (p < 0.05). When the antioxidant vitamin intake of participants was investigated, vitamin E intake in men without CHD was found to be less than in men with CHD (p < 0.05). However, serum vitamin A, vitamin E, and vitamin C levels in men with CHD were found to be lower than in men without CHD (p < 0.05). Based on the results of this study, we propose that high FM, low HDL-C, and low serum antioxidant vitamin levels could be important risk factors for CHD.

Comparison of energy balance-related behaviours and measures of body composition between Turkish adolescents in Turkey and Turkish immigrant adolescents in the Netherlands

OBJECTIVE To explore the influences of migration to a Western country on obesity and related risk factors by comparing measures of body composition and energy balance-related behaviours between Turkish adolescents in Turkey (TR-TR) and adolescents from Turkish immigrant ethnicity in the Netherlands (TR-NL). DESIGN Cross-sectional survey or baseline intervention data from six Dutch school-based studies and one Turkish study. SETTING Primary and secondary schools. SUBJECTS A total of 915 (49 % girls; mean age 13·1 (sd 0·8) years) TR-TR adolescents and 433 (51 % girls; mean age 11·7 (sd 1·3) years) TR-NL adolescents were included. Outcome measures were self-reported sugar-containing beverage consumption, fruit and vegetable intake, screen time, physical activity, measured body height and weight, BMI, waist and hip circumferences, and skinfold thicknesses. RESULTS Our data showed that more TR-NL adolescents were overweight (31 % v. 26 %) and obese (9 % v. 6 %) and had significantly higher mean BMI (21·1 v. 20·0 kg/m2), waist circumference (72·2 v. 71·3 cm) and suprailiac skinfold thickness (19·8 v. 13·1 mm) than TR-TR adolescents. TR-NL adolescents reported significantly higher sugar-containing beverage consumption (1173 v. 115 ml/d), less fruit and vegetable intake (295 v. 647 g/d), less screen time (253 v. 467 min/d) and higher physical activity levels (61 v. 27 min/d) than TR-TR adolescents. CONCLUSIONS Immigrant adolescents in the Netherlands were more often overweight and had a less favourable dietary pattern than their peers in Turkey, while their physical activity and screen time patterns were more favourable. These results suggest that adolescents from Turkish immigrant ethnicity in the Netherlands have adopted lifestyles towards the host culture.

The effects of bariatric surgery on gut microbiota in patients with obesity: a review of the literature

Obesity is a disease with a rapidly increasing prevalence all over the world in recent years. Genetic and environmental factors are involved in the etiology of obesity, and the effect of microbiota on obesity is becoming increasingly clear. Obesity treatment has various treatment modalities such as behavior modification, medical nutrition therapy, physical activity enhancement, and surgical intervention. When other treatment methods are not successful, bariatric surgery is usually resorted to as the treatment method. Some changes such as food choices, the level of hormones and enzymes due to anatomical changes, pH of the stomach, and microbiota are observed after bariatric surgery. Alteration in the microbiota composition after bariatric surgery has also been reported to be important in achieving body weight loss and preserving body weight loss.

Prevalence of metabolic syndrome using NCEP-ATPIII and ınternational dietetics federation (IDF) definitions: A cross- sectional study in Turkish adults

To estimate the prevalence of metabolic syndrome using international dietetics federation (IDF) versus National cholesterol education program; adult treatment panel III (NCEP-ATPIII) definitions in Turkish adults. A cross-sectional study was conducted on a total of 1531 (male 758 and female 773) Turkish adults, aged between 20 to 64 years. Subjects were randomly selected from the general population of Ankara. The overall prevalence of MetS, as defined by NCEP-ATPIII and IDF was 48.2 and 56.4%, respectively. The agreement between National cholesterol education program (NCEP) and IDF definitions was substantial (kappa: 0.79). The prevalence was increased significantly according to increasing age in women, but was not different by age group in men. The prevalence of MetS in all age groups was higher in women. Hypertriglyceridemia and low High-density lipoprotein cholesterol (HDLC) were the criteria of metabolic syndrome (MetS) with the highest prevalence. According to IDF criteria, the frequency of participants with high fasting plasma glucose (FPG) and Waist circumference (WC) was higher than the participants with adult treatment panel III (ATP III) criteria. The prevalence of the MetS was found to be very high, especially in women. The IDF definition resulted in a higher prevalence of metabolic syndrome than the NCEP-ATPIII in the entire Turkish population. The agreement between the IDF and NCEP definitions for metabolic syndrome was very good. Key words: Metabolic syndrome, NCEP-ATPIII, IDF, adult.