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Gary T. Wang

Icos

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Publication

Featured researches published by Gary T. Wang.

Tetrahedron Letters | 1997

Solid phase synthesis of ureas of secondary amines via carbamoyl chloride

Gary T. Wang; Yuanwei Chen; Sheldon Wang; Richard J. Sciotti; Thomas J. Sowin

Abstract Secondary amines attached to a solid support such as the Wang resin can be converted to the corresponding carbamoyl chlorides by treatment with phosgene or triphosgene. Further reaction of the resulting carbamoyl chlorides with primary or secondary amines affords ureas in high yield and chemical purity.

Archive | 2010

Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases

Milan Bruncko; Hong Ding; George Doherty; Steven W. Elmore; Lisa A. Hasvold; Laura Hexamer; Aaron R. Kunzer; Xiaohong Song; Andrew J. Souers; Gerard M. Sullivan; Zhi-Fu Tao; Gary T. Wang; Le Wang; Xilu Wang; Michael D. Wendt; Robert A. Mantei; Todd M. Hansen

Archive | 2003

Sulfonamides having antiangiogenic and anticancer activity

Kenneth M. Comess; Scott A. Erickson; Jack Henkin; Douglas M. Kalvin; Megumi Kawai; Ki H. Kim; Nwe Y. BaMaung; Chang Hoon Park; George S. Sheppard; Anil Vasudevan; Jieyi Wang; David M. Barnes; Steve D. Fidanze; Lawrence Kolaczkowski; Robert A. Mantei; David Park; William J. Sanders; Jason S. Tedrow; Gary T. Wang

Archive | 2001

Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents

Gary T. Wang; Sheldon Wang; Robert G. Gentles

Archive | 2013

Bcl-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases

George Doherty; Steven W. Elmore; Lisa A. Hasvold; Laura Hexamer; Robert A. Mantei; Andrew J. Souers; Gerard M. Sullivan; Zhi-Fu Tao; Gary T. Wang; Le Wang; Xilu Wang; Michael D. Wendt; Todd M. Hansen

Bioorganic & Medicinal Chemistry Letters | 2005

Amino-substituted heterocycles as isosteres of trans-cinnamides: design and synthesis of heterocyclic biaryl sulfides as potent antagonists of LFA-1/ICAM-1 binding.

Gary T. Wang; Sheldon Wang; Robert G. Gentles; Thomas J. Sowin; Sandra Leitza; Edward B. Reilly; Thomas W. von Geldern

Journal of Organic Chemistry | 2001

Synthesis of 2-substituted (+/-)-(2r,3r,5r)-tetrahydrofuran-3,5-dicarboxylic acid derivatives.

Gary T. Wang; Sheldon Wang; Yuanwei Chen; Robert Gentles; Thomas J. Sowin

Archive | 1999

Pyrrolidines as inhibitors of neuraminidases

Clarence J. Maring; Yu-Gui Gu; Hui-Ju Chen; Yuanwei Chen; David A. Degoey; William J. Flosi; Vincent L. Giranda; David J. Grampovnik; Warren M. Kati; Dale J. Kempf; Larry L. Klein; Allan C. Krueger; Zhen Lin; Darold L. Madigan; Keith F. McDaniel; Steven W. Muchmore; Hing Leung Sham; Kent D. Stewart; Vincent S. Stoll; Minghua Sun; Gary T. Wang; Sheldon Wang; Yibo Xu; Ming C. Yeung; Chen Zhao; April Kennedy

Archive | 2010

Pyrimidine inhibitors of kinase activity

Richard F. Clark; Randy L. Bell; Nwe Y. BaMaung; Scott A. Erickson; Steve D. Fidanze; Robert A. Mantei; George S. Sheppard; Bryan K. Sorensen; Gary T. Wang; Jieyi Wang

Archive | 2006

Substituted pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors

George S. Sheppard; Gary T. Wang; Fabio Palazzo; Randy L. Bell; Robert A. Mantei; Jieyi Wang; Robert D. Hubbard; Megumi Kawai; Scott A. Erickson; Nwe Y. BaMaung; Steve D. Fidanze

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Collaboration

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Gerard M. Sullivan

University of Pittsburgh

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Andrew J. Souers

University of California

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Michael D. Wendt

Indiana University Bloomington

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Steven W. Elmore

Ohio State University

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Sheldon Wang

Icos

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Cheol-Min Park

Stanford University

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Clarence J. Maring

Upjohn

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Dale J. Kempf

National Institutes of Health

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Kent D. Stewart

Research Triangle Park

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Minghua Sun

Thermo Fisher Scientific

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