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Science | 1964

SELECTIVE RAT TOXICANT.

Adolph P. Roszkowski; George I. Poos; Richard Joseph Mohrbacher

The maleimide adduct of an unusual fulvene is highly toxic to rats when administered orally or parenterally. It does not induce significant toxic or other biological changes in common house pets and commercially useful mammals and birds when given at dose levels 200 times greater than the dose which is lethal to 50 percent of the rats it is administered to.


Journal of Medicinal Chemistry | 1963

2-AMINO-5-ARYL-2-OXAZOLINES. POTENT NEW ANORECTIC AGENTS.

George I. Poos; John R. Carson; Janet D. Rosenau; Adolph P. Roszkowski; Nancy M. Kelley; Janet McGowin


Archive | 1961

2, 2, 4, 4-tetramethylcyclobutyl compounds

George I. Poos; John T. Suh


Journal of Organic Chemistry | 1961

Ring Cleavage Reactions of trans-2-Amino-3a,4,5,6,7,7a-hexahydrobenzoxazole

Raymond R. Wittekind; Janet D. Rosenau; George I. Poos


Journal of Organic Chemistry | 1961

Bicyclic Bases. III. Isomeric 2-Amino-3-phenylnorbornanes1

George I. Poos; John Kleis; Raymond R. Wittekind; Janet D. Rosenau


Journal of Organic Chemistry | 1963

Bicyclic Bases. V. Epoxidation of 7-Diphenylmethylenenorbornenes1

George I. Poos; Janet D. Rosenau


Journal of Organic Chemistry | 1966

Stereoisomerism of 5-(α-Hydroxy-α-2-pyridylbenzyl)-7-(α-2-pyridylbenzylidene)-5- norbornene-2,3-dicarboximide, a Selective Rat Toxicant1,2

R. J. Mohrbacher; H. R. Almond; E. L. Carson; J. D. Rosenau; George I. Poos


Journal of Organic Chemistry | 1965

2-Amino-5-aryl-2-oxazolines. Tautomerism, Stereochemistry, and an Unusual Reaction

John R. Carson; George I. Poos; Harold R. Almond


Journal of Organic Chemistry | 1964

Hydroxycarbamonitriles from the Reaction of Amino Alcohols with Cyanogen Bromide1

William F. Newhall; George I. Poos; Janet D. Rosenau; John T. Suh


Journal of Organic Chemistry | 1961

Notes- Bicyclic Bases. I. 2-Hydroxymethyl-2-phenyl-3-pyrrolidinylmethyl-5-norbornene

George I. Poos; Margaret Lehman

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