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Dive into the research topics where Gerald Eckardt is active.

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Featured researches published by Gerald Eckardt.


Journal of NeuroInterventional Surgery | 2014

Safety and predictors of aneurysm retreatment for remnant intracranial aneurysm after initial endovascular embolization

Mohamed S. Teleb; Dhruvil J. Pandya; Alicia C. Castonguay; Gerald Eckardt; Rochelle Sweis; Marc A. Lazzaro; Mohammed A Issa; Brian-Fred Fitzsimmons; John R. Lynch; Osama O. Zaidat

Introduction Aneurysmal subarachnoid hemorrhage (SAH) is a rare but devastating form of stroke. Endovascular therapy has been criticized for its higher rate of recanalization and retreatment. The safety and predictors of retreatment are unknown. We report the clinical outcomes, imaging outcomes and predictors for aneurysm retreatment after initial endovascular embolization. Method We identified patients who underwent endovascular retreatment from July 2005 through November 2011. Aneurysm and patient data were collected. Periprocedural complications were reported as intraoperative perforation (IOP) or thromboembolic event (TEE). Aneurysm and patient characteristics were compared between aneurysms requiring retreatment and those not requiring retreatment to evaluate aneurysm retreatment predictors. Results A total of 111/871 (13%) aneurysms underwent retreatment. Two (0.2%) were retreated for recurrent acute SAH, 82 (74%) aneurysms were located in the anterior circulation, 47 (42%) required stent and 5 (5%) required balloon assist during retreatment. There were a total of 5 (5%) IOP and 6 (5%) TEE from which 2 (2%) and 1 (1%) were symptomatic, respectively. Overall symptomatic events rate were 2.7%. Patients were followed up for an average of 15±14 months. Seven (0.8%) aneurysms required a second retreatment without any recurrent SAH. Multivariable analysis revealed an OR for aneurysms requiring retreatment of 2.965 for aneurysms presenting as aneurysmal SAH, 1.791 for aneurysms in the posterior circulation and 1.053 for aneurysms with large dome size. Conclusions Aneurysm retreatment is a safe option without a significant increase in morbidity or mortality. SAH, posterior circulation aneurysms and larger aneurysm dome size are predictors of aneurysms requiring retreatment.


Journal of Orthopaedic Research | 2016

Lumbar spine endplate fractures: Biomechanical evaluation and clinical considerations through experimental induction of injury.

William H. Curry; Frank A. Pintar; Ninh Doan; Ha Son Nguyen; Gerald Eckardt; Jamie L. Baisden; Dennis J. Maiman; Glenn Paskoff; Barry S. Shender; Brian D. Stemper

Lumbar endplate fractures were investigated in different experimental scenarios, however the biomechanical effect of segmental alignment was not outlined. The objectives of this study were to quantify effects of spinal orientation on lumbar spine injuries during single‐cycle compressive loads and understand lumbar spine endplate injury tolerance. Twenty lumbar motion segments were compressed to failure. Two methods were used in the preparation of the lumbar motion segments. Group 1 (n = 7) preparation maintained pre‐test sagittal lordosis, whereas Group 2 (n = 13) specimens had a free‐rotational end condition for the cranial vertebra, allowing sagittal rotation of the cranial vertebra to create parallel endplates. Five Group 1 specimens experienced posterior vertebral body fracture prior to endplate fracture, whereas two sustained endplate fracture only. Group 2 specimens sustained isolated endplate fractures. Group 2 fractures occurred at approximately 41% of the axial force required for Group 1 fracture (p < 0.05). Imaging and specimen dissection indicate endplate injury consistently took place within the confines of the endplate boundaries, away from the vertebral periphery. These findings indicate that spinal alignment during compressive loading influences the resulting injury pattern. This investigation identified the specific mechanical conditions under which an endplate breach will take place. Development of endplate injuries has significant clinical implication as previous research identified internal disc disruption (IDD) and degenerative disc disease (DDD) as long‐term consequences of the axial load‐shift that occurs following a breach of the endplate.


Surgical Neurology International | 2015

Surgical decompression coupled with diagnostic dynamic intraoperative angiography for bow hunter's syndrome.

Ha Son Nguyen; Ninh Doan; Gerald Eckardt; Glen Pollock

Background: Bow hunters syndrome, also known as rotational vertebrobasilar insufficiency, arises from mechanical compression of the vertebral artery during the neck rotation. Surgical options have been the mainstay treatment of choice. Postoperative imaging is typically used to assess adequate decompression. On the other hand, intraoperative assessment of decompression has been rarely reported. Case Description: A 52-year-old male began to see “black spots,” and experienced presyncope whenever he rotated his head toward the right. The patient ultimately underwent a dynamic diagnostic cerebral angiogram, which revealed a dominant right vertebral artery and complete proximal occlusion of the right vertebral artery with the head rotated toward the right. Subsequently, the patient underwent an anterior transcervical approach to the right C6/C7 transverse process. The bone removal occurred along with the anterior wall of the C6 foramen transversarium, followed by the upper portion of the anterior C6 body medially, and the transverse process of C6 laterally. An oblique osseofibrous band was noted to extend across the vertebral artery; it was dissected and severed. An intraoperative cerebral angiogram confirmed no existing compression of the vertebral artery with the head rotated toward the right. The patient recovered from surgery without issues; he denied recurrence of preoperative symptoms at follow-up. Conclusions: The authors report the third instance where intraoperative dynamic angiography was employed with good outcomes. Although intraoperative cerebral angiography is an invasive procedure, which prompts additional risks, the authors believe the modality affords better, real-time visualization of the vertebral artery, allowing for assessment of the adequacy of the decompression. This advantage may reduce the probability for a second procedure, which has its own set of risks, and may counteract the risks involved with intraoperative dynamic angiography.


Surgical Neurology International | 2015

A completely thrombosed, nongiant middle cerebral artery aneurysm mimicking an intra-axial neoplasm.

HaSon Nguyen; Ninh Doan; Gerald Eckardt; Michael Gelsomino; Saman Shabani; WDouglas Brown; Wade M. Mueller; Glen Pollock

Background: Few reports exist regarding thrombosed aneurysms where the initial work up was concerning for a neoplasm. To date, no published reports exist regarding a nongiant thrombosed middle cerebral artery aneurysm, where the primary workup and treatment plan was directed toward a preliminary diagnosis of intra-axial neoplasm. Case Description: We report a 43-year-old female who presented with a generalized tonic-clonic seizure attributed to a lesion along the right superior temporal gyrus. The lesion enhanced on initial magnetic resonance imaging (MRI) of the brain, as well as on follow-up MRI. Subsequent vascular studies and metastatic work up were negative. A craniotomy with image guidance was performed and an intraoperative diagnosis was made of a thrombosed aneurysm along a branch of the middle cerebral artery. The aneurysm was trapped and resected as there was no significant flow from the branch as seen on the prior cerebral angiogram. The patient had an uneventful postoperative course. Conclusion: Completely thrombosed, nongiant aneurysms can mimic an intra-axial neoplasm. Typical imaging features for thrombosed aneurysms may be missed, especially if the aneurysms are small, where imaging characteristics of the intraluminal contents is more difficult to appreciate. Although imaging may be consistent with a neoplastic lesion, there should be suspicion for a potential underlying aneurysm.


Archive | 2016

Remnant Intracranial Aneurysms: Safety and Feasibility of Observation Over Retreatment

Gerald Eckardt; Akinwunmi Oni-Orisan; Brian-Fred Fitzsimmons; Glen Pollock

Subarachnoid hemorrhage resulting from ruptured aneurysms can be a neurologically devastating and fatal event. Aneurysm treatment by endovascular or open surgical means is an established and scientifically backed means of preventing aneurysmal rebleeding. The goal of aneurysm treatment is to completely exclude the aneurysmal portion of the artery from the arterial blood flow. It is not infrequent that a small aneurysmal remnant remains following treatment. Fortunately, the overall risk of rebleeding following aneurysm treatment is low, and in most cases remnants can be observed. The key factor in these cases is serial imaging to detect increases in the size of the remnant or increased flow into the aneurysm that would prompt retreatment.


Annals of Diagnostic Pathology | 2016

Spinal osteoblastic meningioma with hematopoiesis: radiologic-pathologic correlation and review of the literature

Elizabeth J. Cochran; Abraham Schlauderaff; Scott D. Rand; Gerald Eckardt; Shekar N. Kurpad

Spinal meningiomas associated with bone formation and hematopoiesis are rare tumors with only 3 prior case reports in the literature. We describe a case report of a woman who presented with back pain and an isolated event of urinary incontinence. A calcified spinal canal mass at T8 was identified on computed tomographic and magnetic resonance imaging. A gross total resection of the tumor was performed and pathologic examination showed a meningioma, World Health Organization grade 1, containing bone and bone marrow elements. A review of previously reported cases and a discussion of possible mechanisms of bone and hematopoiesis development in meningioma are presented.


World Neurosurgery | 2015

Clinical Correlates of High Cervical Fractional Anisotropy in Acute Cervical Spinal Cord Injury

Aditya Vedantam; Gerald Eckardt; Marjorie C. Wang; Brian D. Schmit; Shekar N. Kurpad


World Neurosurgery | 2017

Diffusion Tensor Imaging Correlates with Short-Term Myelopathy Outcome in Patients with Cervical Spondylotic Myelopathy

Aditya Vedantam; Avinash Rao; Shekar N. Kurpad; Michael B. Jirjis; Gerald Eckardt; Brian D. Schmit; Marjorie C. Wang


Neurosurgery | 2014

High cervical fractional anisotropy as an imaging marker for spinal cord injury.

Aditya Vedantam; Gerald Eckardt; Marjorie C. Wang; Brian D. Schmit; Shekar N. Kurpad


Neurosurgery | 2013

162 Clinical Correlates of High Cervical Fractional Anisotropy in Acute Cervical Spinal Cord Injury

Aditya Vedantam; Gerald Eckardt; Marjorie C. Wang; Brian D. Schmit; Shekar N. Kurpad

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Shekar N. Kurpad

Medical College of Wisconsin

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Aditya Vedantam

Baylor College of Medicine

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Marjorie C. Wang

Medical College of Wisconsin

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Glen Pollock

Medical College of Wisconsin

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Ninh Doan

Medical College of Wisconsin

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Brian D. Stemper

Medical College of Wisconsin

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Dennis J. Maiman

Medical College of Wisconsin

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