Gerhard Franckowiak | Researchain

Archive Network Publication Hotspot Collaboration

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Gerhard Franckowiak is active.

Explore More

Publication

Featured researches published by Gerhard Franckowiak.

European Journal of Pharmacology | 1985

The optical isomers of the 1,4-dihydropyridine BAY K 8644 show opposite effects on Ca channels

Gerhard Franckowiak; Martin Bechem; Matthias Schramm; Gunter Thomas

The optical isomers of the 1,4-dihydropyridine BAY K 8644 were studied in isolated rabbit aorta and heart preparations. The (-)-enantiomer has the known vasoconstricting and positive inotropic properties of the Ca agonistic compound. In contrast, its antipode shows at about 10-50 times higher concentrations the vasodilating and negative inotropic effects of Ca antagonistic drugs. It is concluded that neither simple chemical nor physical actions can be responsible for the opposite effects of Ca antagonistic and Ca agonistic dihydropyridines.

Archive | 1982

Method of combatting coronary and vascular diseases

Gerhard Franckowiak; Horst Boshagen; Friedrich Bossert; Siegfried Goldmann; Horst Meyer; Egbert Wehinger; Jurgen Stoltefuss; Matthias Schramm; Gunter Thomas; Robertson Towart

Archive | 1978

Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use

Friedrich Bossert; Gerhard Franckowiak; Arend Heise; Stanislav Kazda; Horst Meyer; Kurt Stoepel; Robertson Towart; Egbert Wehinger

European Journal of Pharmacology | 1985

Different receptor affinities of the enantiomers of BAY K 8644, a dihydropyridine Ca channel activator

Peter Bellemann; Gerhard Franckowiak

Archive | 1983

Dihydropyridines with a positive inotropic action, new compounds, their use in medicaments, and processes for their preparation

Gerhard Franckowiak; Horst Boshagen; Friedrich Bossert; Siegfried Goldmann; Horst Meyer; Egbert Wehinger; Jurgen Stoltefuss; Matthias Schramm; Gunter Thomas; Robertson Towart

Archive | 1988

Circulation-active dioxyalkylenearyl-dihydropyridines

Gerhard Franckowiak; Albrecht Marhold; Martin Bechem; Rainer Gross; Michael Kayser; Matthias Schramm; Gunther Thomas

Archive | 1976

Compsn. with circulatory and cardiac activity - contains a 3-cyano-1,2-di:hydro-pyridine deriv.

Egbert Wehinger; Friedrich Bossert; Gerhard Franckowiak; Horst Meyer

Archive | 2001

Stable salts of O-acetylsalicylic acid with basic amino acids

Gerhard Franckowiak; Hubert Appolt; Gregor Leifker; Hans-Peter Wirges; Wolfram Ledwoch

Archive | 1986

Circulation-active 1,4-dihydropyridines

Siegfried Goldmann; Jurgen Stoltefuss; Gerhard Franckowiak; Rainer Gross; Matthias Schramm; Gunter Thomas

Archive | 1985

Circulation active dihydropyridine-3-carboxamides

Horst Meyer; Gerhard Franckowiak; Ulrich Rosentreter; Rainer Gross; Gunter Thomas; Matthias Schramm; Michael Kayser; Friedel Seuter; Elisabeth Perzborn; Martin Bechem

Explore More