Gertrude Pischek
University of Vienna
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Featured researches published by Gertrude Pischek.
Monatshefte Fur Chemie | 1974
Gertrude Pischek; E. Kaiser; Heinrich Koch
The test compoundK-2004, a non-teratogenic congener of thalidomide, is quickly absorbed in the rat after oral application and, like thalidomide, degraded hydrolytically. Three metabolites appearing in the urine have been identified. The absence of teratogenicity ofK-2004 is not due to a different metabolism but probably to an altered reactivity towards a recently proposed specific receptor.
Mikrochimica Acta | 1970
Gertrude Pischek; E. Kaiser; Heinrich Koch
ZusammenfassungEine neue dünnschichtchromatographische Methode zur Trennung von Thalidomid und seinen Metaboliten wurde beschrieben. Die günstigsten Ergebnisse erhält man auf Schichten von Kieselgel G bzw. GF254 mit verschiedenen Laufmittelsystemen. DieRf-Werte von Thalidomid und zwölf Hydrolyseprodukten werden angegeben.SummaryA new method for the separation of thalidomide and its metabolites by thin layer chromatography is described. The most favorable results are obtained on layers of Kieselgel G and GF254 respectively with various solvent systems. TheRf-values of thalidomide and twelve hydrolysis products are given.
European Journal of Organic Chemistry | 1972
Heinrich Koch; Johannes Kotlan; Edmond Farkouh; Gertrude Pischek
Archiv Der Pharmazie | 1976
Heinrich Koch; Gertrude Pischek; Gerhard Hitzenberger
Archiv Der Pharmazie | 1976
Gertrude Pischek; Heinrich Koch
Biopharmaceutics & Drug Disposition | 1981
Heinrich Koch; Gertrude Pischek; Margarete Holzbecher; Wolfgang A. Ritschel
Archiv Der Pharmazie | 1978
Gertrude Pischek; Franz Fiebrich; Heinrich Koch
Archiv Der Pharmazie | 1978
Gertrude Pischek; Franz Fiebrich; Heinrich Koch
Archiv Der Pharmazie | 1977
Gertrude Pischek; Franz Fiebrich; Heinrich Koch
Archiv Der Pharmazie | 1975
Gertrude Pischek; Heinrich Koch