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Dive into the research topics where Giuseppe Dodi is active.

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Featured researches published by Giuseppe Dodi.


Techniques in Coloproctology | 2003

Bleeding, incontinence, pain and constipation after STARR transanal double stapling rectotomy for obstructed defecation

Giuseppe Dodi; R. Pietroletti; Giovanni Milito; G. Binda; Mario Pescatori

Abstract.Background:The STARR double stapling procedure (DSP), i. e. transanal anteroposterior rectotomy, has been recently reported as a low-morbidity and effective operation for the treatment of rectocele and internal rectal mucosal prolapse (R-IMP) causing obstructed defecation. We report the postoperative complications and recurrence of symptoms following this novel operation.Patients and methods:Fourteen chronically constipated women with RIMP, aged 36–72 years, presented with either severe complications or recurrence of symptoms following DSP performed by means of two circular staplers. All were followed for a median period of 12 months (range, 2–24) after DPS.Results:Severe rectal bleeding occurred in two cases postoperatively. Persistent severe anal pain was reported by seven patients, all presenting with anxiety. Four of them were multiparous. Three patients had fecal incontinence, both had vaginal deliveries. R-IMP recurred in six, obstructed defecation in seven cases. Four patients needed reintervention, one for suturing the bleeding area, one excising the recurrent prolapse, one for colpocele and one for rectal stricture. Four patients required biofeedback training for non-relaxing puborectalis and two needed psychotherapy.Conclusion:Parity, spastic floor syndrome and psychoneurosis seem to be the risk factors predisposing to failure of DSP, which may be followed by severe complications and early recurrence of symptoms requiring reoperation.


Techniques in Coloproctology | 2002

Complications after stapled hemorrhoidectomy: can they be prevented?

B. Ravo; A. Amato; V. Bianco; P. Boccasanta; C. Bottini; A. Carriero; G. Milito; Giuseppe Dodi; D. Mascagni; S. Orsini; R. Pietroletti; V. Ripetti; G. B. Tagariello

Abstract. Stapled hemorrhoidectomy (SH), a new approach to the treatment of hemorrhoids, removes a circumferential strip of mucosa about four centimeters above the dentate line. A review of 1107 patients treated with SH from twelve Italian coloproctological centers has revealed a 15% (164/1107) complication rate. Immediate complications (first week) were: severe pain in 5.0% of all patients, bleeding (4.2%), thrombosis (2.3%), urinary retention (1.5%), anastomotic dehiscence (0.5%), fissure (0.2%), perineal intramural hematoma (0.1%), and submucosal abscess (0.1%). Bleeding was treated surgically in 24%, with Foley insertion 15%; and by epinephrine infiltration in 2%; 53% of patients with bleeding received no treatment and 6% needed transfusion. One patient with anastomotic dehiscence needed pelvic drainage and colostomy formation. The most common complication after 1 week was recurrence of hemorrhoids in 2.3% of patients, severe pain (1.7%), stenosis (0.8%), fissure (0.6%), bleeding (0.5%), skin tag (0.5%), thrombosis (0.4%), papillary hypertrophy (0.3%) fecal urency (0.2%), staples problems (0.2%), gas flatus and fecal incontinence (0.2%), intramural abscess, partial dehiscence, mucosal septum and intussusception (each <0.1%). Recurrent hemorrhoids were treated by ligation in 40% and by Milligan-Morgan procedure in 32%. All hemorrhoidal thromboses were excised. Anal stenoses were treated by dilatation in 55% and by anoplasty in 45%. Fissure was treated by dilatation in 57%. Most complications (65%) occurred after the surgeon had more than 25 case experiences of stapled hemorrhoidectomy. The most common complication in the first 25 cases of the surgeons experience was bleeding (48%). Even though SH appears to be promising, we feel that a multicenter randomized study with a long-term follow-up comparing SH and banding is necessary before recommending the procedure. Most complications can be avoided by respecting the rectal wall anatomy in the execution of the procedure.


Diseases of The Colon & Rectum | 2008

Results, Outcome Predictors, and Complications after Stapled Transanal Rectal Resection for Obstructed Defecation

Giuseppe Gagliardi; Mario Pescatori; D. F. Altomare; Gian Andrea Binda; Corrado Bottini; Giuseppe Dodi; Vincenzino Filingeri; Giovanni Milito; Marcella Rinaldi; G. P. Romano; Liana Spazzafumo; Mario Trompetto

PurposeObstructed defecation may be treated by stapled transanal rectal resection, but different complications and recurrence rates have been reported. The present study was designed to evaluate stapled transanal rectal resection results, outcome predictive factors, and nature of complications.MethodsClinical and functional data of 123 patients were retrospectively analyzed. All patients had symptoms of obstructed defecation before surgery and had rectocele and/or intussusception. Of them, 85 were operated on by the authors and 38 were referred after stapled transanal rectal resection had been performed elsewhere.ResultsAt a median follow-up of 17 (range, 3–44) months, 65 percent of the patients operated on by the authors had subjective improvement. Recurrent rectocele was present in 29 percent and recurrent intussusception was present in 28 percent of patients. At univariate analysis, results were worse in those with preoperative digitation (P < 0.01), puborectalis dyssynergia (P < 0.05), enterocele (P < 0.05), larger size rectocele (P < 0.05), lower bowel frequency (P < 0.05), and sense of incomplete evacuation (P < 0.05). Bleeding was the most common perioperative complication occurring in 12 percent of cases. Reoperations were needed in 16 patients (19 percent): 9 for recurrent disease. In the 38 patients referred after stapled transanal rectal resection, the most common problems were perineal pain (53 percent), constipation with recurrent rectocele and/or intussusception (50 percent), and incontinence (28 percent). Of these patients, 14 (37 percent) underwent reoperations: 7 for recurrence. Three patients presented with a rectovaginal fistula. One other patient died for necrotizing pelvic fasciitis.ConclusionsStapled transanal rectal resection achieved acceptable results at the cost of a high reoperation rate. Patients with puborectalis dyssynergia and lower bowel frequency may do worse because surgery does not address the causes of their constipation. Patients with large rectoceles, enteroceles, digitation, and a sense of incomplete evacuation may have more advanced pelvic floor disease for which stapled transanal rectal resection, which simply removes redundant tissue, may not be adequate. This, together with the complications observed in patients referred after stapled transanal rectal resection, suggests that this procedure should be performed by colorectal surgeons and in carefully selected patients.


Colorectal Disease | 2007

Set-up and statistical validation of a new scoring system for obstructed defaecation syndrome.

D. F. Altomare; L. Spazzafumo; Marcella Rinaldi; Giuseppe Dodi; R. Ghiselli; V. Piloni

Objective  There is no objective means to assess the obstructed defaecation syndrome (ODS), to allow evaluation of outcome or to compare the efficacy of treatment including surgery. The study aimed to validate a disease‐specific index to quantify severity to allow assessment of the results of treatment in clinical trials, to permit comparison between them.


British Journal of Surgery | 2004

Disappointing long-term results of the artificial anal sphincter for faecal incontinence†

D. F. Altomare; G. A. Binda; Giuseppe Dodi; F. La Torre; G. P. Romano; Marcella Rinaldi; E. Melega

1Department of General Surgery and Liver Transplantation, University of Bari, Bari, 2Coloproctological Unit, Galliera Hospital, Genoa, 3Section of Surgical Clinic II, Department of Surgical and Oncologic Sciences, University of Padua, Padua, 4Department of Surgical Sciences, University of Rome ‘La Sapienza’, Rome and 5Department of Emergency Surgery, ‘S. Moscati’ Hospital, Avellino, Italy Correspondence to: Dr D. F. Altomare, Department of Emergency and Organ Transplantation, Section of General Surgery and Liver Transplantation, University of Bari, Policlinico, piazza G. Cesare 11, 70124 Bari, Italy (e-mail: [email protected])


Diseases of The Colon & Rectum | 1986

Hot or cold in anal pain

Giuseppe Dodi; F. Bogoni; A. Infantino; P. Pianon; L. M. Mortellaro; Mario Lise

In 26 volunteers without anorectal complaints, and in 31 patients with anorectal problems such as hemorrhoidal disease, anal fissure, and proctalgia fugax, baseline resting anal canal pressures were recorded manometrically for 5 minutes at room temperature (23° C). In 16 volunteers (Group A) and 21 patients (group B) anorectal manometry was then performed while the anus was immersed in water at varying temperatures (5° C, 23° C, and 40° C). In ten volunteers (Group A′) and ten patients (Group B′) resting pressures were recorded for an additional 30 minutes following immersion for 5 minutes at 40° C. In all subjects (at leastP<0.01), resting anal canal pressures diminished significantly from baseline after immersion at 40° C, but remained unchanged in all subjects after immersion at 5° C and 23° C. In Group A′, anal canal pressures remained significantly reduced for 15 minutes (P<0.02). In Group B′, significant reduction in resting pressure lasted 30 minutes (P<0.02). Wet heat applied to the anal sphincter apparatus significantly and reproducibly decreased resting anal canal pressures over time, and therefore was likely to benefit patients after anorectal operations and those with anorectal pain.


Gastroenterology Research and Practice | 2010

An Open-Label, Noncomparative, Multicenter Study to Evaluate Efficacy and Safety of NASHA/Dx Gel as a Bulking Agent for the Treatment of Fecal Incontinence

Giuseppe Dodi; Johannes Jongen; Fernando de la Portilla; Manoj Raval; D. F. Altomare; Paul-Antoine Lehur

Fecal incontinence (FI) is the involuntary loss of rectal contents through the anal canal. Reports of its prevalence vary from 1–21%. Studies, have demonstrated a positive effect on FI symptoms with injectable bulking agents. This study evaluated the safety and efficacy of NASHA/Dx gel in the treatment of FI. One hundred fifteen eligible patients suffering from FI received 4 injections of 1 mL NASHA/Dx gel. Primary efficacy was based on data from 86 patients that completed the study. This study demonstrated a ≥50% reduction from baseline in the number of FI episodes in 57.1% of patients at 6 months, and 64.0% at 12 months. Significant improvements (P < .001) were also noted in total number of both solid and loose FI episodes, FI free days, CCFIS, and FIQL scores in all 4 domains. The majority of the treatment related AEs (94.9%) were mild or moderate intensity, and (98.7%) of AEs resolved spontaneously, or following treatment, without sequelae. Results of this study indicate NASHA/Dx gel was efficacious in the treatment of FI. Treatment effect was significant both in reduction of number of FI episodes and disease specific quality of life at 6 months and lasted up to 12 months after treatment.


Pain | 1987

Modifications of [3H]imipramine binding sites in platelets of chronic pain patients treated with mianserin

Guido Magni; Francesca Andreoli; Carlo Arduino; Diego Arsie; F. Ceccherelli; Francesco Ambrosio; Giuseppe Dodi; Mario Eandi

&NA; Tritiated imipramine binding to whole platelets was measured in 16 chronic pain patients who were free from major depression, and in a control group. The maximum binding was significantly lower in chronic pain patients than in the control group, whereas the binding affinity was not significantly different. Twelve patients were treated with mianserin for 21 days; this produced a significant improvement in the mean scores for pain (evaluated with the McGill Questionnaire) and depressive symptoms (assessed with the Zung Self‐Rating Scale). The improvement in both types of symptom was accompanied by a significant mean increase in the density of the [3H]imipramine binding sites without modifications in the values of the constant of affinity. All the patients who responded well to treatment (N = 8) had a family history of depressive spectrum disorders (DSD), while none of those who failed to respond had a first degree relative with DSD.


American Journal of Roentgenology | 2007

Error Count of Radiopaque Markers in Colonic Segmental Transit Time Study

Fabio Pomerri; Anna Chiara Frigo; Francesco Grigoletto; Giuseppe Dodi; Pier Carlo Muzzio

OBJECTIVE The objective of our study was to evaluate the feasibility and efficacy of a radiologic technique in increasing colon visibility in colonic transit time studies. Three radiologists counted segmental colonic radiopaque markers in two patient groups, based on classic criteria in the first group and also on a colonic barium trace in the second. Agreement between marker counts was assessed using method comparison analysis. CONCLUSION With the barium trace technique, the anatomic conspicuity of colonic segments is improved, a correct segmental marker count can be obtained, and colonic inertia can be more easily distinguished from distal constipation.


Diseases of The Colon & Rectum | 1990

Role of proctography in severe constipation

A. Infantino; A. Masin; P. Pianon; Giuseppe Dodi; G. Del Favero; Fabio Pomerri; Mario Lise

As referred to in the literature, patients complaining of constipation may have a spastic or, in the case of chronic straining, weak pelvic floor. Twenty-two severely constipated patients who did not improve after a high fiber diet were submitted to whole gut transit time (TT), proctographic, and anorectal manometric studies. A control group consisting of five subjects for TT, five subjects for proctogram, and ten subjects for manometry was also studied. Transit time was delayed (P< 0.001) in all patients. Manometry in the constipated group showed a high rectal threshold (64.1vs.17.1 ml of air,P< 0.01), but no other significant difference. Proctograms in 10 of 22 patients (Group A) showed no differences in the anorectal angle (ARA) and in its distance from the pubococcygeal line (DLPC) in respect to the control group; 12 of 22 patients (Group B) had a paradoxical closure of the ARA at straining in respect to resting position (101.2†vs.120.1†), and a higher DLPC than Group A and the control group in all positions studied. There was no difference in TT for rectal stasis of radiopaque markers between the two pathologic groups. Patients in Group B were older than patients in Group A (55.3vs.42.9 years,P<0.05). In conclusion, proctograms showed alterations of the pelvic floor, but there was no correlation between proctographic data and rectal or colonic stasis of the radiopaque markers, or clinic severity of constipation, but a correlation between ages did exist.

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